Navigation Links
Asbestos exposure, asbestosis, and smoking combined greatly increase lung cancer risk
Date:4/11/2013

The chances of developing lung cancer associated with asbestos exposure, asbestosis and smoking are dramatically increased when these three risk factors are combined, and quitting smoking significantly reduces the risk of developing lung cancer after long-term asbestos exposure, according to a new study.

"The interactions between asbestos exposure, asbestosis and smoking, and their influence on lung cancer risk are incompletely understood," said lead author Steven B. Markowitz, MD DrPH, professor of occupational and environmental medicine at the School of Earth & Environmental Sciences at Queens College in New York. "In our study of a large cohort of asbestos-exposed insulators and more than 50,000 non-exposed controls, we found that each individual risk factor was associated with increased risk of developing lung cancer, while the combination of two risk factors further increased the risk and the combination of all three risk factors increased the risk of developing lung cancer almost 37-fold."

The findings were published online ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

The study included 2,377 long-term North American insulators and 54,243 male blue collar workers with no history of exposure to asbestos from the Cancer Prevention Study II. Causes of death were determined from the National Death Index.

Among non-smokers, asbestos exposure increased the rate of dying from lung cancer 5.2-fold, while the combination of smoking and asbestos exposure increased the death rate more than 28-fold. Asbestosis increased the risk of developing lung cancer among asbestos-exposed subjects in both smokers and non-smokers, with the death rate from lung cancer increasing 36.8-fold among asbestos-exposed smokers with asbestosis.

Among insulators who quit smoking, lung cancer morality dropped in the 10 years following smoking cessation from 177 deaths per 10,000 among current smokers to 90 per 10,000 among those who quit. Lung cancer rates among insulators who had stopped smoking more than 30 years earlier were similar to those among insulators who had never smoked.

There were a few limitations to the study, including the fact that smoking status and asbestosis were evaluated only once and that some members of the control group could have been exposed to relatively brief periods of asbestos.

"Our study provides strong evidence that asbestos exposure causes lung cancer through multiple mechanisms," said Dr. Markowitz. "Importantly, we also show that quitting smoking greatly reduces the increased lung cancer risk seen in this population."


'/>"/>

Contact: Nathaniel Dunford
ndunford@thoracic.org
American Thoracic Society
Source:Eurekalert

Related medicine news :

1. Lung Cancer Asbestos Victims Center Urges Retired Energy Workers Who Had Exposure At Their Workplace And Now Have Lung Cancer To Call them About Compensation
2. Lung Cancer Asbestos Victims Center Urges Retired Aircraft Manufacturing Workers Diagnosed With Lung Cancer To Call Them If They Were Exposed To Asbestos At Work
3. Lung Cancer Asbestos Victims Center Now Urges Nonsmoker Lung Cancer Victims Who Were exposed To Asbestos In Their Workplace To Call Them About Possible Compensation
4. Lung Cancer Asbestos Victims Center Now Urges US Navy Veterans With Any Type Of Lung Cancer To Call Them If They Were Exposed To Asbestos On A Ship-Get Compensated
5. Lung Cancer Asbestos Victims Center Now Urges Victims Of Any Kind Of Lung Cancer Victim Who Were Exposed To Asbestos At Their Workplace To Call Them About Compensation
6. Lung Cancer Asbestos Victims Center Now Urges Lung Cancer Victims To Contact Them About Possibly Significant Financial Compensation If They Were Exposed To Asbestos At Work
7. Lung Cancer Asbestos Victims Center Now Urges US Navy Veterans Who Were Exposed To Asbestos On A Ship And Now Have Any Kind Of Lung Cancer To Call Them About Compensation
8. Lung Cancer Asbestos Victims Center Now Urges Families Of A Retired Factory Worker To Call Them If Their Loved One Has Lung Cancer And Was Exposed To Asbestos At Work
9. Lung Cancer Asbestos Victims Center Now Urges Retired Nonsmoker Industrial Workers Who Have Been Diagnosed With Any Type Of Lung Cancer To Call Them About Compensation
10. Lung Cancer Asbestos Victims Center Now Urges Shipyard Workers Diagnosed With Any Type Of Lung Cancer If They Were Exposed To Asbestos
11. Lung Cancer Asbestos Victims Center Now Urges US Navy Veterans With Lung Cancer To Call Them If They Had Heavy Exposure To Asbestos On A US Navy Ship
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Conventional wisdom ... of success. In terms of the latter, setting the bar too high can result ... more than just slow progress toward their goal. , Research from PsychTests.com ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was ... his family verbally and physically. , “When something upset him, he couldn’t control his emotions,” ... He would throw rocks at my other children and say he was going to kill ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Comfort Keepers® ... American Cancer Society and the Road To Recovery® program to drive cancer patients to ... and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... to recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and the ... in the world, and the most handsome men, look naturally attractive. Plastic surgery ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Venture Construction ... Classic Tournament held on June 20th at the Woodmont Country Club at 1201 ... Wings, an organization dedicated to helping service members that have been wounded in battle ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... -- Research and Markets has announced the addition ... report to their offering. ... The World Market for Companion Diagnostics covers the world ... in the report includes the following: , ... by Region (N. America, EU, ROW), 2015-2020 , World ...
(Date:6/24/2016)... , Belgium , June 24, ... VNRX), today announced the appointment of Dr. ... Directors as a Non-Executive Director, effective June 23, ... Audit, Compensation and Nominations and Governance Committees.  As ... Futcher will provide independent expertise and strategic counsel ...
(Date:6/23/2016)... , June 23, 2016 Research ... Devices Global Market - Forecast to 2022" report to ... the treatment method for the patients with kidney failure, it ... excess fluid from the patient,s blood and thus the treatment ... potassium and chloride in balance. Increasing number ...
Breaking Medicine Technology: