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Artificial liver for drug tests
Date:6/25/2009

z. "This time was sufficient to analyze and evaluate the functions. A longer period of activity is possible, however." The researchers established that the cells work in a similar way to those in the body. They detoxify, break down drugs and build up proteins. These are important pre-conditions for drug tests or transplants, as the effect of a substance can change when transformed or broken down many drugs are only metabolized into their therapeutic active form in the liver, while others can develop poisonous substances. The researchers have demonstrated the basic possibilities for use of the tissue models liver, skin, intestine and windpipe. At the moment, the test system is being examined. Within two years it could provide a safer alternative to animal experiments.


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Contact: Heike Mertsching
heike.mertsching@igb.fraunhofer.de
49-711-970-4117
Fraunhofer-Gesellschaft
Source:Eurekalert  

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