Navigation Links
Arthritis in Children Linked to Infections
Date:5/1/2012

TUESDAY, May 1 (HealthDay News) -- Children with juvenile arthritis have higher rates of bacterial infection when hospitalized than children without arthritis, a new study says.

While taking high-dose steroids was associated with a higher infection risk among kids with arthritis, other arthritis drugs -- methotrexate and tumor necrosis factor alpha (TNF) inhibitors -- were not.

Researchers analyzed Medicaid data on nearly 8,500 children with juvenile idiopathic arthritis and more than 360,000 arthritis-free children. Idiopathic means that a disease occurs without a known cause.

Pharmacy claims were examined to determine arthritis patients' use of drugs that suppress the immune system, including high-dose glucocorticoids (steroids), methotrexate and TNF inhibitors, according to the study published May 1 in the journal Arthritis & Rheumatism.

Kids with arthritis who were not currently treated with methotrexate or TNF inhibitors had a 2-fold increase in bacterial infection rates while hospitalized compared to children without arthritis, study leader Dr. Timothy Beukelman, of the University of Alabama at Birmingham, said in a journal news release. "This finding suggests the inflammatory or autoimmune process may predispose children to infection regardless of therapy," Beukelman said.

Among children with juvenile arthritis, the rate of infection associated with methotrexate or TNF inhibitor treatment was similar.

After they adjusted for methotrexate and TNF inhibitor use among the arthritis patients, the researchers found that the rate of bacterial infection among those who took high-dose steroids (10 milligrams or more of prednisone a day) was more than twice that of those who did not take steroids.

Limiting steroids may reduce the risk of serious infection in children with arthritis, Beukelman concluded.

Nearly 300,000 children in the United States have juvenile idiopathic arthritis, according to the American College of Rheumatology.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about juvenile arthritis.

-- Robert Preidt

SOURCE: Arthritis & Rheumatism, news release, May 1, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Children with juvenile arthritis have higher rates of bacterial infection
2. One-third of adult Americans with arthritis battle anxiety or depression
3. Mayo Clinic: Obesity epidemic fueling rise in rheumatoid arthritis among women
4. Gastro Woes Often Strike Rheumatoid Arthritis Patients
5. Treat Rheumatoid Arthritis Early and Aggressively: Guidelines
6. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
7. Lupus, Rheumatoid Arthritis Linked to Fertility Woes, Miscarriage
8. Women with rheumatoid arthritis and lupus give birth to fewer children
9. Too Many Rheumatoid Arthritis Patients Inactive, Study Finds
10. 2 in 5 adults with rheumatoid arthritis are physically inactive
11. Knee Arthritis May Speed Up Process Linked to Cell Aging
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the ... national organization of elder law and special needs planning attorneys. “Membership in ElderCounsel helps ... provides a forum to network with elder law attorneys nationwide,” said Somekh. , ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that ... insurance companies have a waiver for care if the client has a cognitive impairment ... family pays for care, is often waived, so the benefits from their insurance start ...
(Date:10/13/2017)... ... 13, 2017 , ... Ellevate Network, the leading network for professional women, brought ... gender equality at their inaugural Summit in New York City in June. The event ... audience of over 3 million. To watch the Mobilize Women video, click here ...
(Date:10/13/2017)... ... , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has ... least understood books in the Holy Scriptures, Revelation. The Book of Revelation paints a ... centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins says that ...
(Date:10/13/2017)... ... 13, 2017 , ... Coveros, a leader in agile coaching ... contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile ... of Agile methodologies in a consistent and high value manner across CMS programs. ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... -- Caris Life Sciences ® , a leading innovator in ... medicine, today announced that St. Jude Medical Center,s Crosson ... as its 17 th member. Through participation with ... Institute will help develop standards of care and best ... cancer treatment more precise and effective. ...
(Date:10/7/2017)... , Oct. 6, 2017   Provista, ... more than $100 billion in purchasing power, today announced ... and information. The Newsroom is the online ... industry trends, infographics, expert bios, news releases, slideshows and ... access to a wealth of resources at their fingertips, ...
(Date:10/2/2017)... 2017 Diplomat Pharmacy, Inc. (NYSE: ... Consulting, LLC , and named its founder as Diplomat,s ... Tennessee , will operate under Diplomat ... service offerings for health care partners to include IT ... "In an interoperable world, technology delivers comprehensive ...
Breaking Medicine Technology: