Navigation Links
Arthritis Treatment Linked to Liver Problems in Study
Date:6/18/2012

By Randy Dotinga
HealthDay Reporter

MONDAY, June 18 (HealthDay News) -- A "medical food" called Limbrel, which doctors prescribe to treat osteoarthritis of the knee, was linked to several cases of liver disease in a small study, but the effects so far seem to be rare and easily reversible.

Still, patients who take Limbrel, also known as flavocoxid, should be aware of the potential for liver problems, said study lead author Dr. Naga Chalasani, director of the division of gastroenterology and hepatology at Indiana University School of Medicine, in Indianapolis.

Patients should not assume that "medical foods," such as Limbrel, are 100 percent safe, he added.

In the United States, medical foods are not subjected to the clinical trials required of prescription drugs before coming to market.

According to Primus Pharmaceuticals, Inc., maker of Limbrel, the main ingredients of the pills are plant elements known as bioflavonoids, specifically baicalin and catechins. The company says Limbrel helps improve mobility and relieve joint discomfort and stiffness related to arthritis.

For the new study, Chalasani and colleagues analyzed 877 cases of liver injury and found four linked with Limbrel. The researchers said it's "highly likely" that the product caused the liver problems in three of the patients and possible in the other one.

Symptoms included nausea, fatigue and yellow skin, Chalasani said. The four patients were women between 57 and 68 years old who showed signs of liver illness between one and three months after taking Limbrel.

They recovered within weeks of discontinuing the drug.

"Our report provides convincing evidence that flavocoxid is capable of causing clinically apparent, acute liver injury," the study authors wrote. They also noted that the pharmaceutical company has discovered 31 possible cases of liver problems among more than 284,000 users since the dru
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Menopausal Age May Affect Rheumatoid Arthritis Severity
2. Smoking negatively affects response to anti-TNF treatment in patients with rheumatoid arthritis
3. Early menopause predicts a milder form of rheumatoid arthritis
4. Personalizing biologic treatment to individual patients with rheuatoid arthritis is cost-effective
5. For Juvenile Arthritis, Pill May Work as Well as Needle
6. Injection of methotrexate not superior to oral therapy in juvenile arthritis treatment
7. Mayo Clinic: Standard heart disease risk tools underrate danger in rheumatoid arthritis
8. Scientists identify new target to battle rheumatoid arthritis
9. Research With Dogs Points to Early Test for Arthritis
10. Dinosaurs May Have Suffered From Arthritis
11. New biomarker test predicts arthritis at much earlier stage, MU researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Arthritis Treatment Linked to Liver Problems in Study
(Date:4/19/2015)... (PRWEB) April 19, 2015 Carinsurancehints.com has released ... who have to claim auto insurance benefits . ... pictures and gather all the necessary information for claiming auto ... a good insurance plan to cover most of the damages. ... insurance benefits for an accident. , Drivers can compare ...
(Date:4/19/2015)... New court documents issued by the ... Lipitor lawsuits ( http://www.lipitorlawsuitcenter.com/ ) continue to mount in ... of South Carolina. According to the April 15th filing, ... the proceeding on behalf of individuals who allegedly developed ... cholesterol-lowering statin. This represents an increase of 110 filings ...
(Date:4/19/2015)... Indiana Fiber Network, LLC (IFN), ... a major bandwidth upgrade infrastructure service to AdamsWells ... Craigville Telephone Company, Inc. (DBA AdamsWells), one of ... protected 10 Gigabit internet transport ring. , ... Sales and Marketing, AdamsWells expanded Internet bandwidth will ...
(Date:4/18/2015)... The Residential Senior Care Franchises ... years. The industry, which provides residential and personal-care services ... for themselves, has boomed on account of the aging ... seniors with memory impairment. As a result, IBISWorld expects ... 4.1% to $1.9 billion over the five years to ...
(Date:4/18/2015)... April 18, 2015 Carinsurancehints.com has released a ... plans that offer financial protection against fire damage. ... pay benefits in case their vehicle is set intentionally on ... caused by rioting or by other things. , It ... on a single website http://www.carinsurancehints.com/ , in just ...
Breaking Medicine News(10 mins):Health News:An Online Guide About Claiming Auto Insurance Benefits After an Accident 2Health News:Lipitor Lawsuits Mount, as New Court Report Shows More Than 100 Filings Added to Federal Litigation Since March 2Health News:Lipitor Lawsuits Mount, as New Court Report Shows More Than 100 Filings Added to Federal Litigation Since March 3Health News:AdamsWells Internet Telecom TV Expands Bandwidth via Indiana Fiber Network, LLC 2Health News:Residential Senior Care Franchises in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Residential Senior Care Franchises in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:Online Auto Insurance Quotes For Plans That Cover Fire Damages! 2
... ARBOR, Mich.--- A new Bluetooth system designed primarily for blind ... world to tell pedestrians about points of interest along their ... orientation system was developed at the University of Michigan. Researchers ... , "Blind people can get from point A to point ...
... IBD have high risk of infection by hepatitis viruses ... disease, they need blood transfusions, and sometimes surgical and ... to alert health professionals about prevention and early diagnosis ... used in IBD treatment worsen the HBV liver disease. ...
... Bluegrass Bariatric Surgical,Associates announced today that the ... registry designed to evaluate the results of an,innovative ... ROSE (Revision Obesity Surgery, Endolumenal). The ROSE procedure ... pouch and stoma to,approximate the original post-gastric bypass ...
... a "Viable Alternative" to Standard Injections - 69% ... of Their Diabetes, AUSTIN, Texas, Sept. 17 ... small, disposable injection port about the size of ... 1 and type 2,diabetes, participants, differences in glycosylated ...
... Amazon.com Should Voters Ask Just How Important ... 17 In this presidential,election year, a vice-president ... ever been before. Yet, author and researcher Harry ... where a vice-president nomination seriously,impacted our country and ...
... AMN Healthcare, the largest,healthcare staffing company in ... International (OGPI), today announced AMN,s,endorsement of a Code ... the United States., A task force, including ... and licensure bodies developed the "Voluntary,Code of Ethical ...
Cached Medicine News:Health News:New Bluetooth system orients blind and sighted pedestrians 2Health News:New Bluetooth system orients blind and sighted pedestrians 3Health News:The prevalence of hepatitis B virus infection in inflammatory bowel disease patients 2Health News:Final Patient Enrolled In Large Data Registry of Incisionless Gastric Pouch and Stoma Reduction Procedure 2Health News:Final Patient Enrolled In Large Data Registry of Incisionless Gastric Pouch and Stoma Reduction Procedure 3Health News:Final Patient Enrolled In Large Data Registry of Incisionless Gastric Pouch and Stoma Reduction Procedure 4Health News:Diabetes Spectrum Reports a Study Assessing the i-port(R) Injection Port for Administration of Insulin 2Health News:Diabetes Spectrum Reports a Study Assessing the i-port(R) Injection Port for Administration of Insulin 3Health News:A Conspiracy of Silence: Impact on History The Health and Death of Franklin D. Roosevelt 2Health News:AMN Healthcare, OGPI Endorse AcademyHealth's Code of Conduct for Recruitment of Foreign-Educated Nurses 2Health News:AMN Healthcare, OGPI Endorse AcademyHealth's Code of Conduct for Recruitment of Foreign-Educated Nurses 3
(Date:4/17/2015)... NORTH CHICAGO, Ill. , April 17, 2015  AbbVie ... ABBV) today announced that it has extended the expiration of ... of common stock of Pharmacyclics, Inc. to 5 p.m., ... 2015. On April 17, 2015, AbbVie also ... Hart-Scott-Rodino Antitrust Improvements Act in order to provide the FTC ...
(Date:4/17/2015)... Nonin Medical, a global leader in noninvasive medical monitoring, ... Steve Bucholz will retire May 1. Company founder ... Chief Executive Officer. In addition, Mr. Isaacson will continue ... transition to David Noel , Chief Financial Officer. ... to Nonin Medical,s growth," Mr. Isaacson said. "Under Steve,s ...
(Date:4/17/2015)... 2015 Research and Markets ( ... "Medical Device Outsourcing - Global Strategic Business ... This report analyzes the worldwide markets for Medical ... Device Categories: Class I, Class II, and Class ... report Include - Radiology, Orthopedic, Neurology, Cardiology, and ...
Breaking Medicine Technology:AbbVie Extends Exchange Offer to Acquire Pharmacyclics, Inc. 2AbbVie Extends Exchange Offer to Acquire Pharmacyclics, Inc. 3AbbVie Extends Exchange Offer to Acquire Pharmacyclics, Inc. 4Nonin Medical's Philip Isaacson Expands CEO Role; President and COO Steve Bucholz to Retire May 1 2Medical Device Outsourcing (Radiology, Orthopedic, Neurology, Cardiology, and Others) Market 2015 - Global Strategic Business Report 2Medical Device Outsourcing (Radiology, Orthopedic, Neurology, Cardiology, and Others) Market 2015 - Global Strategic Business Report 3
... 2011  Saint-Gobain Performance Plastics has upgraded its capabilities ... art laser engraving system. The system allows Saint-Gobain ... of all hose assemblies, piping and components, providing ... Plastics can engrave crimp collars on hose assemblies ...
...  Breckenridge Pharmaceutical, Inc. announced that the U.S. Food ... New Drug Application (ANDA) for Methscopolamine Bromide Tablets. ... a prescription medicine that is used as adjunctive therapy ... by Kenwood Therapeutics. The current market is approximately $7M, ...
Cached Medicine Technology:Saint-Gobain Introduces Laser Engraving for Hose Assemblies 2
... affordable solution for low volume workloads, or ... includes a variety of clotting assays, such ... 1000 also offers bar code capability to ... it's backed by superior technology that has ...
... The SYNCHRON CX9 ALX system is ... time-consuming manual processes by as much as ... lower your total costs. Featuring the AccuSense® ... and an expanded test menu, the CX9 ...
... SYNCHRON CX5-S workstation offers a ... targeted to the mid-size lab ... samples per day. Like all ... is easy to use, easy ...
... mid- to high-volume lab, the SYNCHRON LX ... time-consuming manual tasks by as much as ... access, STAT, HCFA panels and batch profiling ... chemistries, General chemistries, TDMs, DATs, Thyroids, Specialty, ...
Medicine Products: