Navigation Links
Arteries Age Twice as Fast in Smokers
Date:4/26/2010

Study shows progressive stiffening, which leads to blockages

MONDAY, April 26 (HealthDay News) -- It's well-known that smoking is bad for the heart and other parts of the body, and researchers now have chronicled in detail one reason why -- because continual smoking causes progressive stiffening of the arteries.

In fact, smokers' arteries stiffen with age at about double the speed of those of nonsmokers, Japanese researchers have found.

Stiffer arteries are prone to blockages that can cause heart attacks, strokes and other problems.

"We've known that arteries become more stiff in time as one ages," said Dr. William B. Borden, a preventive cardiologist and assistant professor of medicine at Weill Cornell Medical Center in New York City. "This shows that smoking accelerates the process. But it also adds more information in terms of the role smoking plays as a cause of cardiovascular disease."

For the study, researchers at Tokyo Medical University measured the brachial-ankle pulse wave velocity, the speed with which blood pumped from the heart reaches the nearby brachial artery, the main blood vessel of the upper arm, and the faraway ankle. Blood moves slower through stiff arteries, so a bigger time difference means stiffer blood vessels.

Looking at more than 2,000 Japanese adults, the researchers found that the annual change in that velocity was greater in smokers than nonsmokers over the five to six years of the study.

Smokers' large- and medium-sized arteries stiffened at twice the rate of nonsmokers', according to the report released online April 26 in the Journal of the American College of Cardiology by the team from Tokyo and the University of Texas at Austin.

That's no big surprise, said Borden, noting there's definitely a dose-response relationship. "The more smoking, the more arterial stiffening there is per day."

The study authors measured stiffening by years, not by day, but the damaging effect of smoking was clear over the long run.

The finding gives doctors one more argument to use in their continuing effort to get smokers to quit, said Dr. David Vorchheimer, associate professor of medicine and cardiology at Mount Sinai Medical Center in New York City.

"One of the challenges that physicians face when trying to get people to stop smoking is the argument, 'Well, I've been smoking for years and nothing has happened to me yet,'" Vorchheimer said. "What this study emphasizes is that the damage is cumulative. The fact that you've gotten away with it so far doesn't mean you'll get away with it forever."

The stiffening of arteries is "one of the earliest and most subtle changes that occur" in smokers' bodies, Vorchheimer said. "Some people's arteries can be safe for a few years. The good thing about that is the possibility that the damage will heal if you give up smoking."

Another notable aspect of the study was the analysis of the effect of smoking on C-reactive protein, a molecular marker of inflammation that appears to play a role in cardiovascular disease. The study found no relationship between blood levels of C-reactive protein and arterial stiffening.

That finding adds one more piece to the puzzle of C-reactive protein and cardiovascular disease that researchers are trying to assemble, Borden said. "We're still trying to understand the role of CRP, whether it's a cause or a marker of other factors that lead to cardiovascular disease," he said.

More information

The physical damage done by smoking is outlined by the U.S. National Library of Medicine.



SOURCES: William B. Borden, M.D., M.B.A., assistant professor, medicine, Nanette Laitman Clinical Scholar in Public Health, Weill Cornell Medical Center, New York City; David Vorchheimer, M.D., associate professor, medicine, Mount Sinai Medical Center, New York City; April 26, 2010, Journal of the American College of Cardiology, online


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New method to grow arteries could lead to biological bypass for heart disease
2. Secondhand Smoke Starts Damaging Arteries in Childhood
3. Popular Diet Plans Can Unclog Arteries
4. Stents as good as surgery for clogged carotid arteries
5. American Stroke Association Late-Breaking Science Report: Surgery, Stenting to Open Blocked Neck Arteries Similar in Safety, Efficacy, But Show Differences in Stroke, Heart Attack and Death Rates at Certain Ages
6. Cooling inflammation for healthier arteries
7. CT Scans Deemed Best for Checking Heart Arteries
8. Severe asymptomatic heart disease may accompany narrowing in leg arteries
9. Severe Asymptomatic Heart Disease May Accompany Narrowing in Leg Arteries
10. Twice as Many Women May Soon Be Diagnosed With Gestational Diabetes
11. Midlife crisis: Unmarried older women twice as likely to lack health insurance, study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... Dallas, Texas (PRWEB) , ... February 08, 2016 , ... The Valentine’s Season is famous ... family members and significant others that they are loved. This year, for more than ... much they cost - just won't be enough to remind them of the lives they’ve ...
(Date:2/8/2016)... Hilton Head Island, SC (PRWEB) , ... February 08, 2016 , ... ... Head and surrounding areas with a vital new community enrichment program, has teamed up ... to local women and children suffering from intimate abuse. To support all those victimized ...
(Date:2/8/2016)... ... ... Remember the old saying “rub some dirt on it”? Perhaps you should try using ... the health benefits of integrating clay into a daily diet are numerous, as clay ... speaker, Perry A~ has since dedicated her life to learning about the benefits of ...
(Date:2/8/2016)... Gaithersburg, MD (PRWEB) , ... February 08, 2016 ... ... (AHCC) is excited to share this important news! AHCC and the Home Health ... (AHA) Coding Clinic, CMS' designee for official ICD coding guidance and clarifications, to ...
(Date:2/8/2016)... ... February 08, 2016 , ... According to research ... U.S. require dental technicians to be certified or obtain continuing education. To increase ... the “What’s In Your Mouth?” campaign to inform dentists and patients about the ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... , Feb. 8, 2016 ... addition of the "Label-Free Detection Market ... to 2020" report to their offering. ... the addition of the "Label-Free Detection ... Forecasts to 2020" report to their ...
(Date:2/8/2016)... Therapeutics, Inc. announced today that the United States Patent and ... the use of NephroFlow to treat acute kidney injury (AKI). ... "We are pleased to secure our rights to such a ... HemaFlo,s founder, said, "We are pleased to secure our rights ... Dale Peterson , PhD, HemaFlo,s founder, said, "We are pleased ...
(Date:2/8/2016)... , Feb. 8, 2016  Dynatronics Corporation (NASDAQ: ... advanced-technology medical devices and rehabilitation equipment for the ... the Denver Broncos, football team for winning the ... Jr. , Chairman and Chief Executive Officer.  "The ... we look forward to enhancing their athletic achievements ...
Breaking Medicine Technology: