Navigation Links
Arteries Age Twice as Fast in Smokers
Date:4/26/2010

Study shows progressive stiffening, which leads to blockages

MONDAY, April 26 (HealthDay News) -- It's well-known that smoking is bad for the heart and other parts of the body, and researchers now have chronicled in detail one reason why -- because continual smoking causes progressive stiffening of the arteries.

In fact, smokers' arteries stiffen with age at about double the speed of those of nonsmokers, Japanese researchers have found.

Stiffer arteries are prone to blockages that can cause heart attacks, strokes and other problems.

"We've known that arteries become more stiff in time as one ages," said Dr. William B. Borden, a preventive cardiologist and assistant professor of medicine at Weill Cornell Medical Center in New York City. "This shows that smoking accelerates the process. But it also adds more information in terms of the role smoking plays as a cause of cardiovascular disease."

For the study, researchers at Tokyo Medical University measured the brachial-ankle pulse wave velocity, the speed with which blood pumped from the heart reaches the nearby brachial artery, the main blood vessel of the upper arm, and the faraway ankle. Blood moves slower through stiff arteries, so a bigger time difference means stiffer blood vessels.

Looking at more than 2,000 Japanese adults, the researchers found that the annual change in that velocity was greater in smokers than nonsmokers over the five to six years of the study.

Smokers' large- and medium-sized arteries stiffened at twice the rate of nonsmokers', according to the report released online April 26 in the Journal of the American College of Cardiology by the team from Tokyo and the University of Texas at Austin.

That's no big surprise, said Borden, noting there's definitely a dose-response relationship. "The more smoking, the more arterial stiffening there is per day."

The study authors measured stiffening by years, not by day, but the damaging effect of smoking was clear over the long run.

The finding gives doctors one more argument to use in their continuing effort to get smokers to quit, said Dr. David Vorchheimer, associate professor of medicine and cardiology at Mount Sinai Medical Center in New York City.

"One of the challenges that physicians face when trying to get people to stop smoking is the argument, 'Well, I've been smoking for years and nothing has happened to me yet,'" Vorchheimer said. "What this study emphasizes is that the damage is cumulative. The fact that you've gotten away with it so far doesn't mean you'll get away with it forever."

The stiffening of arteries is "one of the earliest and most subtle changes that occur" in smokers' bodies, Vorchheimer said. "Some people's arteries can be safe for a few years. The good thing about that is the possibility that the damage will heal if you give up smoking."

Another notable aspect of the study was the analysis of the effect of smoking on C-reactive protein, a molecular marker of inflammation that appears to play a role in cardiovascular disease. The study found no relationship between blood levels of C-reactive protein and arterial stiffening.

That finding adds one more piece to the puzzle of C-reactive protein and cardiovascular disease that researchers are trying to assemble, Borden said. "We're still trying to understand the role of CRP, whether it's a cause or a marker of other factors that lead to cardiovascular disease," he said.

More information

The physical damage done by smoking is outlined by the U.S. National Library of Medicine.



SOURCES: William B. Borden, M.D., M.B.A., assistant professor, medicine, Nanette Laitman Clinical Scholar in Public Health, Weill Cornell Medical Center, New York City; David Vorchheimer, M.D., associate professor, medicine, Mount Sinai Medical Center, New York City; April 26, 2010, Journal of the American College of Cardiology, online


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New method to grow arteries could lead to biological bypass for heart disease
2. Secondhand Smoke Starts Damaging Arteries in Childhood
3. Popular Diet Plans Can Unclog Arteries
4. Stents as good as surgery for clogged carotid arteries
5. American Stroke Association Late-Breaking Science Report: Surgery, Stenting to Open Blocked Neck Arteries Similar in Safety, Efficacy, But Show Differences in Stroke, Heart Attack and Death Rates at Certain Ages
6. Cooling inflammation for healthier arteries
7. CT Scans Deemed Best for Checking Heart Arteries
8. Severe asymptomatic heart disease may accompany narrowing in leg arteries
9. Severe Asymptomatic Heart Disease May Accompany Narrowing in Leg Arteries
10. Twice as Many Women May Soon Be Diagnosed With Gestational Diabetes
11. Midlife crisis: Unmarried older women twice as likely to lack health insurance, study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer care, ... remain in the eye of the beholder, according to experts who offered insights and ... Journal of Managed Care. For the full issue, click here . , For ...
(Date:6/26/2016)... , ... June 26, 2016 , ... Pixel Film Studios ... X. , "Film editors can give their videos a whole new perspective by using ... - CEO of Pixel Film Studios. , ProSlice Levels contains over 30 Different ...
(Date:6/26/2016)... NC (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind and ... to be personalized through a fitness app. The fitness app plans to fix the two ... currently only offer a one size fits all type program , They don’t ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts ... applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention ... health care topics including advance care planning, healthcare costs and patient and family ...
(Date:6/25/2016)... Miami, FL (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton ... Plant City Observer , brings up a new, often overlooked aspect of head lice: ... The closing for fumigation is not a common occurrence, but a necessary one in the ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... June 27, 2016  VMS Rehab Systems, Inc. ( ... take whatever measures required to build a strong and ... is currently listed on the OTC Markets-pink current trading ... and CEO, "We are seeing an anomaly in market ... not only by the Company, but shareholders and market ...
(Date:6/24/2016)... 2016  Consumers have taken a more active ... more emphasis on patient outcomes. ... the pharmaceutical industry have evolved beyond just providing ... are focusing on becoming more patient-oriented across their ... services that improve health. ...
(Date:6/24/2016)... June 24, 2016  Global Blood Therapeutics, Inc. (GBT) ... developing novel therapeutics for the treatment of grievous ... the closing of its previously announced underwritten public ... the public offering price of $18.75 per share. ... offered by GBT. GBT estimates net proceeds from ...
Breaking Medicine Technology: