Navigation Links
Arteries Age Twice as Fast in Smokers
Date:4/26/2010

Study shows progressive stiffening, which leads to blockages

MONDAY, April 26 (HealthDay News) -- It's well-known that smoking is bad for the heart and other parts of the body, and researchers now have chronicled in detail one reason why -- because continual smoking causes progressive stiffening of the arteries.

In fact, smokers' arteries stiffen with age at about double the speed of those of nonsmokers, Japanese researchers have found.

Stiffer arteries are prone to blockages that can cause heart attacks, strokes and other problems.

"We've known that arteries become more stiff in time as one ages," said Dr. William B. Borden, a preventive cardiologist and assistant professor of medicine at Weill Cornell Medical Center in New York City. "This shows that smoking accelerates the process. But it also adds more information in terms of the role smoking plays as a cause of cardiovascular disease."

For the study, researchers at Tokyo Medical University measured the brachial-ankle pulse wave velocity, the speed with which blood pumped from the heart reaches the nearby brachial artery, the main blood vessel of the upper arm, and the faraway ankle. Blood moves slower through stiff arteries, so a bigger time difference means stiffer blood vessels.

Looking at more than 2,000 Japanese adults, the researchers found that the annual change in that velocity was greater in smokers than nonsmokers over the five to six years of the study.

Smokers' large- and medium-sized arteries stiffened at twice the rate of nonsmokers', according to the report released online April 26 in the Journal of the American College of Cardiology by the team from Tokyo and the University of Texas at Austin.

That's no big surprise, said Borden, noting there's definitely a dose-response relationship. "The more smoking, the more arterial stiffening there is per day."

The study authors measured stiffening by years, not by day, but the damaging effect of smoking was clear over the long run.

The finding gives doctors one more argument to use in their continuing effort to get smokers to quit, said Dr. David Vorchheimer, associate professor of medicine and cardiology at Mount Sinai Medical Center in New York City.

"One of the challenges that physicians face when trying to get people to stop smoking is the argument, 'Well, I've been smoking for years and nothing has happened to me yet,'" Vorchheimer said. "What this study emphasizes is that the damage is cumulative. The fact that you've gotten away with it so far doesn't mean you'll get away with it forever."

The stiffening of arteries is "one of the earliest and most subtle changes that occur" in smokers' bodies, Vorchheimer said. "Some people's arteries can be safe for a few years. The good thing about that is the possibility that the damage will heal if you give up smoking."

Another notable aspect of the study was the analysis of the effect of smoking on C-reactive protein, a molecular marker of inflammation that appears to play a role in cardiovascular disease. The study found no relationship between blood levels of C-reactive protein and arterial stiffening.

That finding adds one more piece to the puzzle of C-reactive protein and cardiovascular disease that researchers are trying to assemble, Borden said. "We're still trying to understand the role of CRP, whether it's a cause or a marker of other factors that lead to cardiovascular disease," he said.

More information

The physical damage done by smoking is outlined by the U.S. National Library of Medicine.



SOURCES: William B. Borden, M.D., M.B.A., assistant professor, medicine, Nanette Laitman Clinical Scholar in Public Health, Weill Cornell Medical Center, New York City; David Vorchheimer, M.D., associate professor, medicine, Mount Sinai Medical Center, New York City; April 26, 2010, Journal of the American College of Cardiology, online


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New method to grow arteries could lead to biological bypass for heart disease
2. Secondhand Smoke Starts Damaging Arteries in Childhood
3. Popular Diet Plans Can Unclog Arteries
4. Stents as good as surgery for clogged carotid arteries
5. American Stroke Association Late-Breaking Science Report: Surgery, Stenting to Open Blocked Neck Arteries Similar in Safety, Efficacy, But Show Differences in Stroke, Heart Attack and Death Rates at Certain Ages
6. Cooling inflammation for healthier arteries
7. CT Scans Deemed Best for Checking Heart Arteries
8. Severe asymptomatic heart disease may accompany narrowing in leg arteries
9. Severe Asymptomatic Heart Disease May Accompany Narrowing in Leg Arteries
10. Twice as Many Women May Soon Be Diagnosed With Gestational Diabetes
11. Midlife crisis: Unmarried older women twice as likely to lack health insurance, study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2016)... ... 28, 2016 , ... May 26, 2016- In search of the K. Warriors, ... event of “K Warriors” on June 4, 2016 at Ashbury Hotel and Suites 600 ... sponsored and hosted by Shaolin Institute and sanctioned by KSF (Kungfu Sanda Federation), This ...
(Date:5/28/2016)... , ... May 28, 2016 , ... In a part of the city where’s it’s ... new farm-to-table Kelowna restaurants is hoping to attract diners with a taste for ... Suites officially opened the doors to Cornerstone Grill, an urban casual restaurant focusing on ...
(Date:5/27/2016)... ... May 27, 2016 , ... Southland Log Homes , designer ... timber frame barn kits, which can be found on its website at SouthlandLogHomes.com. , ... barn plans, and they highlight the craftsmanship of timber post and beam construction. ...
(Date:5/27/2016)... ... May 27, 2016 , ... W.S. Badger Co. ... today that it has been recognized as one of the best small businesses for ... named as one of nine small businesses providing progressive benefits to new parents on ...
(Date:5/27/2016)... ... May 27, 2016 , ... With over 60 percent ... the demand for a sustainable product to aid in the rehabilitation process has steadily ... the recovery of individuals with hemiplegia due to stroke. , Ekso Bionics has now ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... SPRINGS, Florida , May 25, 2016 ... Business Conference & Expo earlier this month, the numbers ... As revenues continue to climb into the billions, more ... the newly released 4th Edition State of Legal Marijuana ... Frontier, a cannabis-focused data-analysis firm, much of the increase ...
(Date:5/25/2016)... , May 25, 2016 Digital Health ... to it by the US Patent and Trademark ... technology includes proprietary processes for electronic opt-­in and ... and wellness programs, HIPAA compliance and otherwise. ... "Our technology allows for ...
(Date:5/25/2016)... , May 25, 2016 ... the precision of circulating tumour DNA (ctDNA) analysis ... the appointment of Professor Clive Morris ... leadership across the clinical development programme, scientific collaborations, ... help deliver significant improvements in clinical outcomes for ...
Breaking Medicine Technology: