Navigation Links
Are there gender differences in anti-HIV drug efficacy?
Date:8/9/2012

New Rochelle, NY, August 9, 2012Women comprise nearly half of the HIV-infected population worldwide, but these 15.5 million women tend to be under-represented in clinical trials of anti-HIV drug therapies. The U.S. Food and Drug Administration (FDA) has created a database from 40 clinical studies to assess gender differences in the efficacy of antiretroviral treatments. The results of this study are presented in an article in AIDS Patient Care and STDs, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the AIDS Patient Care and STDs website at http://www.liebertpub.com/apc.

Guoxing Soon and coauthors from the FDA and University of Texas Southwestern Medical Center, Dallas, TX, found that women represented only about 20% of the subjects in randomized clinical trials submitted to the FDA between 2000 and 2008. The article "Meta-Analysis of Gender Differences in Efficacy Outcomes for HIV-Positive Subjects in Randomized Controlled Clinical Trials of Antiretroviral Therapy (2000-2008)" compares the effectiveness of anti-HIV drug regimens reported for women versus men overall and among various subgroups.

The authors found no statistically or clinical significant differences between women and men in outcomes with regard to viral load after 48 weeks. However, they did report significant gender differences favoring males based on subgroup analyses.

"This is a critical area of research in terms of developing new HIV therapies," says Editor-in-Chief Jeffrey Laurence, MD, Director of the Laboratory for AIDS Virus Research at Weill Medical College of Cornell University, New York, NY. "Mounting evidence indicates that metabolism of certain drugs varies in men vs. women, and side effects that interfere with adherence to these medications may also be manifest differently."


'/>"/>
Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Page: 1

Related medicine news :

1. New findings by GW researcher break tanning misconceptions: There is no such thing as a safe tan
2. Dr. Carol Francis Radio Talk Show Discusses Sexual Abuse as Related to "Coach" Jerry Sandusky; Interview With Abuse Survivor Teresa Joyce, Author of "There's A Fine Line"
3. Love Knows No Gender Difference
4. Report Calls for Counseling Guidelines for Treating Transgender People
5. APA task force recommends treatment guidelines and position statements on transgender persons
6. Health-care law gender gap
7. Mayo Clinic study links healthy muscle mass to healthy bones, finds differences by gender
8. Racial differences in diabetes diagnostic thresholds
9. Study finds significant skull differences between closely linked groups
10. Hair samples from infants show exposure to anti-HIV drugs in the womb and during breast-feeding
11. Taking Anti-HIV Meds Prior to Exposure May Help Prevent Infection
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Are there gender differences in anti-HIV drug efficacy?
(Date:8/30/2014)... (PRWEB) August 31, 2014 Fast ... build websites. Top10BestSEOHosting.com has recently compared many professional ... ( http://www.hostmonster.com/track/seohosts ) and Arvixe are the suppliers ... is hard to find a good fast hosting ... on hosting features, uptime, server speed and customer ...
(Date:8/30/2014)... Midland, TX (PRWEB) August 30, 2014 ... Quotes Pros company to introduce better prices to consumers ... insurance plans can be found when using the open ... The national lookup system available to use this year ... for insurance based on general location and not from ...
(Date:8/30/2014)... Colorado (PRWEB) August 30, 2014 Daily Gossip ... called the Make Him Desire You program, who shows a ... , The author of this method says that the program ... , The Make Him Desire You review indicates that the ... amazing insider advice and his great techniques to make a ...
(Date:8/30/2014)... 2014 The term nutraceuticals is ... Nutraceuticals is a source of healthy-dietary supplements that ... food sources. Nutraceutical ingredients have certain curative effects ... body. Nutraceutical health products include factors such as ... more. Although nature is the most bountiful source ...
(Date:8/30/2014)... After offering hyperbaric oxygen therapy ... past several years, Dr. Roy Schmidt and the ... a scholarship program for veterans who have been ... held this summer to discuss veterans’ needs ( ... shed light on the large number of veterans ...
Breaking Medicine News(10 mins):Health News:Fastest Web Hosting Suppliers In 2014 Announced By Top10BestSEOHosting.com 2Health News:Term Life Insurance Rates Now Found Nationally by New Insurer Finder Tool 2Health News:Make Him Desire You Review Reveals Powerful Formula to Make a Man Emotionally Addicted 2Health News:A Granular Analysis of the Nutraceutical Ingredients Market by Transparency Market Research 2Health News:A Granular Analysis of the Nutraceutical Ingredients Market by Transparency Market Research 3Health News:A Granular Analysis of the Nutraceutical Ingredients Market by Transparency Market Research 4Health News:Tennessee Hyperbaric Center Offering HBOT Scholarships to Veterans 2
... SAN DIEGO, Nov. 5 Volcano Corporation (Nasdaq: VOLC ... products for the diagnosis and treatment of coronary and peripheral ... third quarter of fiscal 2009. , The results for the ... percent over revenues of $44.1 million in the third quarter ...
... mix of bacteria for each person , THURSDAY, Nov. ... on and within the human body has uncovered the fact ... Nations of germs. , The scientists, using sophisticated gene-sequencing technologies, ... on and within the body. They found a wide variability ...
... countries , THURSDAY, Nov. 5 (HealthDay News) -- The United ... health-care practices, according to a new international survey of primary ... the other countries in the survey, yet a majority of ... care, and a wide majority of primary care physicians don,t ...
... ... , ... -- Now there are some five-star reasons for Houston-area Medicare beneficiaries to choose ... of its annual Consumer Assessment of Healthcare Providers and Systems (CAHPS) survey, and KelseyCare ...
... SHENZHEN, China, Nov. 5 /PRNewswire-Asia/ ... ), China,s leading stem cell research,and regenerative ... an,agreement with Yokohama-based Biomaster Inc. ( http://www.biomaster.jp ... Biomaster specializes in research,and commercialization of adipose-based stem ...
... COLUMBIA, S.C., Nov. 5 Companion Life Insurance Co. ... to offer its dental policyholders preferred pricing on travel ... , Traveling abroad for credentialed dental care, also known ... Prices at the international clinics average 60 to 80 ...
Cached Medicine News:Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 2Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 3Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 4Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 5Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 6Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 7Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 8Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 9Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 10Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 11Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 12Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 13Health News:Volcano Reports 22 Percent Increase in Third Quarter Revenues 14Health News:Germs Mingle Most on Palms, Feet, Forearms 2Health News:Germs Mingle Most on Palms, Feet, Forearms 3Health News:Doctors Point Out Gaps in U.S. Health Care 2Health News:Local Medicare Advantage Plan Gets Five-Star Ratings from Medicare 2Health News:Local Medicare Advantage Plan Gets Five-Star Ratings from Medicare 3Health News:Beike Biotechnology Invests in Leading Japanese Regenerative Medicine Co., Biomaster Inc. 2Health News:Beike Biotechnology Invests in Leading Japanese Regenerative Medicine Co., Biomaster Inc. 3Health News:Beike Biotechnology Invests in Leading Japanese Regenerative Medicine Co., Biomaster Inc. 4Health News:Companion Life Adds Dental Tourism Option to Help Policyholders Save 2Health News:Companion Life Adds Dental Tourism Option to Help Policyholders Save 3
(Date:8/29/2014)... 29, 2014  A Boston Scientific Corporation (NYSE: ... stent removability and preliminary long term stricture resolution ... the August issue of the peer-reviewed journal, Gastroenterology. ... is being conducted in 11 countries and five ... metal stents (FCSEMS) after extended indwell (i.e., up ...
(Date:8/29/2014)... Calif. , Aug. 29, 2014 Medina ... as CEO and member of the Board of Directors ... of medical device development and commercialization experience, including over ... Mr. Engelson previously served as a Partner of the ... President and CEO of two Foundry start-ups. Mr. Engelson ...
(Date:8/29/2014)... WEST JORDAN, Utah , Aug. 29, 2014 /PRNewswire/ ... Imaging Solutions, has acquired Polaris Medical Imaging, a leader ... CT scanners. This strategic acquisition allows BC Technical to ... their capabilities, specifically within MR and CT modalities. ... lower cost service," said Mark Alvarez , president ...
Breaking Medicine Technology:Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 2Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 3Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 4Medina Medical Announces Erik T. Engelson Joins as Chief Executive Officer 2BC Technical Acquires Polaris Medical Imaging 2
... 6, 2012 Silence Therapeutics plc ... RNA interference (RNAi) therapeutics company, announces the ... Collaboration and Delivery Collaboration with its partner AstraZeneca and ... and AstraZeneca was initiated in 2007 and was extended ...
... MADISON HEIGHTS, Mich., Jan. 5, 2012  Yesterday, workers at VPH ... voted for representation with the United Food and Commercial ... security and a voice on the job. The vote ... which workers clearly demonstrated they stood unmoved and united ...
Cached Medicine Technology:Research and Development Collaboration Update 2Research and Development Collaboration Update 3Research and Development Collaboration Update 4
MBS 0.2 ml satellite block unit with height adjusting heated lid, 96 well standard block - holds 96 x 0.2ml tubes or 1 x 96 well plate (includes tube thermistor)...
... is Thermo Electron's most advanced personal gradient ... to use sophisticated onboard software and a ... to offer performance, accuracy and simplicity in ... of customer driven features built up on ...
... Advanced Design With Exceptional Performance ... user interface might be the ... the MyCycler is designed for ... at a premium, its small ...
96 well thermocycler with unique High Temperature Range (HTR) Peltier technology for fastest available heating and cooling rates up to 4C/sec with High Pressure Lid for automated sealing of PCR plate...
Medicine Products: