Navigation Links
Are there gender differences in anti-HIV drug efficacy?
Date:8/9/2012

New Rochelle, NY, August 9, 2012Women comprise nearly half of the HIV-infected population worldwide, but these 15.5 million women tend to be under-represented in clinical trials of anti-HIV drug therapies. The U.S. Food and Drug Administration (FDA) has created a database from 40 clinical studies to assess gender differences in the efficacy of antiretroviral treatments. The results of this study are presented in an article in AIDS Patient Care and STDs, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the AIDS Patient Care and STDs website at http://www.liebertpub.com/apc.

Guoxing Soon and coauthors from the FDA and University of Texas Southwestern Medical Center, Dallas, TX, found that women represented only about 20% of the subjects in randomized clinical trials submitted to the FDA between 2000 and 2008. The article "Meta-Analysis of Gender Differences in Efficacy Outcomes for HIV-Positive Subjects in Randomized Controlled Clinical Trials of Antiretroviral Therapy (2000-2008)" compares the effectiveness of anti-HIV drug regimens reported for women versus men overall and among various subgroups.

The authors found no statistically or clinical significant differences between women and men in outcomes with regard to viral load after 48 weeks. However, they did report significant gender differences favoring males based on subgroup analyses.

"This is a critical area of research in terms of developing new HIV therapies," says Editor-in-Chief Jeffrey Laurence, MD, Director of the Laboratory for AIDS Virus Research at Weill Medical College of Cornell University, New York, NY. "Mounting evidence indicates that metabolism of certain drugs varies in men vs. women, and side effects that interfere with adherence to these medications may also be manifest differently."


'/>"/>
Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Page: 1

Related medicine news :

1. New findings by GW researcher break tanning misconceptions: There is no such thing as a safe tan
2. Dr. Carol Francis Radio Talk Show Discusses Sexual Abuse as Related to "Coach" Jerry Sandusky; Interview With Abuse Survivor Teresa Joyce, Author of "There's A Fine Line"
3. Love Knows No Gender Difference
4. Report Calls for Counseling Guidelines for Treating Transgender People
5. APA task force recommends treatment guidelines and position statements on transgender persons
6. Health-care law gender gap
7. Mayo Clinic study links healthy muscle mass to healthy bones, finds differences by gender
8. Racial differences in diabetes diagnostic thresholds
9. Study finds significant skull differences between closely linked groups
10. Hair samples from infants show exposure to anti-HIV drugs in the womb and during breast-feeding
11. Taking Anti-HIV Meds Prior to Exposure May Help Prevent Infection
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Are there gender differences in anti-HIV drug efficacy?
(Date:7/31/2015)... IL (PRWEB) , ... July 31, 2015 , ... Ticket ... which is currently going on in Chicago at Grant Park. The festival will ... corner of North America to Chicago for the annual Lollapalooza. This unique and ...
(Date:7/31/2015)... ... July 31, 2015 , ... The 2nd annual Ride to ... Downtown Memphis on October 3, 2015. The Ride to Fight On is a cycling ... between Methodist Healthcare, The West Clinic and The University of Tennessee Health Science Center. ...
(Date:7/31/2015)... ... July 31, 2015 , ... Facebook, Twitter, Linkedin ... re-branded their social media profiles to better connect with the public. The agency ... find information, share insights and opinions. The Rally Insurance Group, Inc.’s pledge to ...
(Date:7/31/2015)... ... July 31, 2015 , ... According to the article published July 27 ... Pasadena courthouse was contained and extinguished by the city’s fire department before it caused major ... at the time of the fire, and it was a fire alarm system that tipped ...
(Date:7/31/2015)... ... 2015 , ... Cosmetic Town has proven itself as the ... surgery procedures including, but not limited to, abdominoplasty, blepharoplasty, rhinoplasty and septoplasty. ... fillers. , Staying up to date with the latest cosmetic trends has ...
Breaking Medicine News(10 mins):Health News:Cheap 2015 Lollapalooza Tickets: Ticket Down Slashes Ticket Prices on Lollapalooza Tickets at Grant Park in Chicago for Saturday, August 1st and Sunday, August 2nd 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 3Health News:Rally Insurance Group, Inc. Connects to Customers Through Re-branded Social Media Profiles 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 3Health News:Cosmetic Town: Now Providing Interactive And Vital Medical Knowledge 2
... visits flood affected states of Tabasco and Chiapas, ... recording artist Clay Aiken today wrapped up the first,leg ... southeast Mexico by,participating in a gift exchange and "sing ... camp erected for flood victims., (Photo: http://www.newscom.com/cgi-bin/prnh/20071225/AQTU002 ...
... Kaiser Permanente is,providing 40 Atlanta-area nonprofit organizations with ... over $1.4 million in grant funds to support,local ... to,$250,000 and focus on increasing access to health ... nursing and pharmacy,scholarships; and other community health programs., ...
... /Xinhua-PRNewswire/ -- Chindex International,Inc. (Nasdaq: CHDX ), ... products in the People,s Republic of China, announced ... listing of its common stock on,the NASDAQ Global ... Capital,Market to the NASDAQ Global Market has been ...
... media and PPC ads ... pointed to a landing ... of Key Technology, has hired Denver-based interactive marketing agency,90octane to ... (PPC) advertising will send prospects to a landing,page featuring the ...
... veterans shows that those with injuries to certain parts ... stress disorder (PTSD). The findings, from the National ... Center, suggest that drugs or pacemaker-like devices aimed at ... treatments for PTSD. , PTSD involves the persistent reliving ...
... ... Extension, TUCSON, Ariz., Dec. 21 ImaRx Therapeutics,Inc. ... submitted a lot release,request to the Food and Drug ... urokinase drug product. Urokinase, ImaRx,s first,commercially available FDA-approved product, ...
Cached Medicine News:Health News:Clay Aiken & Family Celebrate Christmas With Survivors of Mexico's Floods 2Health News:Kaiser Permanente Provides $1.4 Million in Holiday Gifts to 40 Metro Atlanta Nonprofits 2Health News:Kaiser Permanente Provides $1.4 Million in Holiday Gifts to 40 Metro Atlanta Nonprofits 3Health News:Chindex International, Inc. Announces Transfer to NASDAQ Global Market 2Health News:Chindex International, Inc. Announces Transfer to NASDAQ Global Market 3Health News:90octane Selected as Interactive Marketing Agency for Symetix Lead Generation Program 2Health News:Study suggests some brain injuries reduce the likelihood of post-traumatic stress disorder 2Health News:Study suggests some brain injuries reduce the likelihood of post-traumatic stress disorder 3Health News:ImaRx Therapeutics Submits Urokinase Data to FDA Supporting Extended Expiration Dating 2Health News:ImaRx Therapeutics Submits Urokinase Data to FDA Supporting Extended Expiration Dating 3
(Date:7/31/2015)...  Seeger Weiss LLP is reporting that on July 13, ... to C.R. Bard, the manufacturer of Inferior vena cava ... violations the agency found at two of Bard,s facilities. Bard ... cited them during Inspectional Observations that occurred on November 18, ... AZ , location and on October 6, 2014, through ...
(Date:7/31/2015)... , July 31, 2015  Boston Children,s Hospital ... from 3D printing of their anatomy before undergoing ... cerebrovascular malformations (abnormalities in the brain,s blood vessels) ... online today in the Journal of Neurosurgery: ... 3D printing and synthetic resins to create custom, ...
(Date:7/31/2015)... Scientific, Inc. (Nasdaq: SMLR ), a company that ... physician groups, today reported financial results for the second ... the second quarter of 2015, Semler reported continued progress ... over quarter revenue growth of 8%, and quarter over ... of 18%," said Doug Murphy-Chutorian, M.D., chief executive officer ...
Breaking Medicine Technology:Seeger Weiss LLP Reports That The FDA Has Issued A Warning Letter To IVC Filter Manufacturer, C.R. Bard 2Seeger Weiss LLP Reports That The FDA Has Issued A Warning Letter To IVC Filter Manufacturer, C.R. Bard 33D Printing Helps Doctors Rehearse Complex Brain Procedures 23D Printing Helps Doctors Rehearse Complex Brain Procedures 33D Printing Helps Doctors Rehearse Complex Brain Procedures 4Semler Reports Second Quarter 2015 Financial Results 2Semler Reports Second Quarter 2015 Financial Results 3Semler Reports Second Quarter 2015 Financial Results 4Semler Reports Second Quarter 2015 Financial Results 5Semler Reports Second Quarter 2015 Financial Results 6
... 27 ChemoCentryx, Inc., today announced that ... PROTECT-1 Study (the Prospective Randomized Oral Therapy ... (CCX282-B) in patients with moderate-to-severe Crohn,s disease. ... antagonist showed clinical efficacy in a 12-week ...
... NANJING, China, Oct. 27 /PRNewswire-Asia/ -- Simcere Pharmaceutical Group ... specializing in the development, manufacturing, and marketing of branded ... it will report its unaudited financial results for the ... 11, 2010, before the market opens in the United ...
Cached Medicine Technology:ChemoCentryx Reports One-Year Results from PROTECT-1 Study Demonstrating Traficet-EN's Effectiveness in Treating Patients with Crohn's Disease at the United European Gastroenterology Federation (UEGW) Meeting 2ChemoCentryx Reports One-Year Results from PROTECT-1 Study Demonstrating Traficet-EN's Effectiveness in Treating Patients with Crohn's Disease at the United European Gastroenterology Federation (UEGW) Meeting 3ChemoCentryx Reports One-Year Results from PROTECT-1 Study Demonstrating Traficet-EN's Effectiveness in Treating Patients with Crohn's Disease at the United European Gastroenterology Federation (UEGW) Meeting 4ChemoCentryx Reports One-Year Results from PROTECT-1 Study Demonstrating Traficet-EN's Effectiveness in Treating Patients with Crohn's Disease at the United European Gastroenterology Federation (UEGW) Meeting 5Simcere Pharmaceutical Group to Announce Third Quarter 2010 Financial Results on Thursday, November 11, 2010 2
Inquire...
... Protects the skin over extended ... skin barrier is the barrier of ... the added benefit of it being ... size. Security and confidence assured with ...
Inquire...
Inquire...
Medicine Products: