Navigation Links
Are manometric findings different between the patients with erosive and nonerosive disease?
Date:12/8/2009

Gastroesophageal reflux disease (GERD) is defined as the pathological retrograde movement of gastric contents into the esophagus. Various esophageal motility disturbances which may be important in reflux are observed in patients with GERD. The main esophageal motility disorder in these patients is ineffective esophageal motility (IEM). Increased acid clearance time and IEM have been shown to be strongly associated with isolated proximal reflux. However, there are no data that conclusively link motility disorders with isolated distal reflux (IDR).

A research team, led by Dr. Yasemin Ozin from Turkey Yuksek Ihtisas Training and Research Hospital investigated manometric measurements in patients with IDR and compare the findings in individuals with and without erosive esophagitis.

Their study will be published on November 21, 2009 in the World Journal of Gastroenterology. In their study, patients with symptoms of GERD were evaluated with esophageal manometry, 24-h ambulatory pH monitoring, and upper gastrointestinal endoscopy. Among patients with isolated distal reflux, the manometric findings of patients who had erosive disease and non-erosive disease were compared. There were no significant differences between the isolated distal reflux group and control group with respect to age, body mass index, and esophageal body contraction amplitude. Mean lower esophageal sphincter pressure was significantly higher in the control group. There were no differences between the erosive reflux disease and non-erosive reflux disease subgroups with respect to mean esophageal body contraction amplitude (EBCA), lower esophageal sphincter pressure, or DeMeester score. However, IEM was observed only in patients with erosive reflux disease.

The authors provided more insight into the pathophysiology of reflux disease. The finding of very low EBCA being observed only in patients with erosive disease might be helpful in identifying these patients.

Reference: Ozin Y, Dagli U, Kuran S, Sahin B. Manometric findings in patients with isolated distal gastroesophageal reflux. World J Gastroenterol 2009; 15(43): 5461-5464

http://www.wjgnet.com/1007-9327/15/5461.asp

Correspondence to: Dr. Yasemin Ozin, Gastroenterology Department, Turkey Yuksek Ihtisas Training and Research Hospital, Kızılay Sokak, 06040 Sıhhıye, Ankara, Turkey. yoozderin@gmail.com

Telephone: +90-312-3061827 Fax: +90-312-29596 47


'/>"/>
Contact: Ye-Ru Wang
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Related medicine news :

1. New Gene Findings Will Help Guide Treatment in Infant Leukemia
2. Northern California Cancer Centers Findings on Breast Cancer and Secondhand Smoke Released Internationally by the American Association for Cancer Research
3. The Leukemia & Lymphoma Society Available to Comment on Findings Presented at American Society of Hematology Conference
4. New findings suggest strategy to help generate HIV-neutralizing antibodies
5. Findings that should speed the development of drugs for Parkinsons disease
6. Shire Reports Findings From an Analysis Examining Emotional Lability in Children With ADHD Taking Vyvanse(R) (lisdexamfetamine dimesylate) Capsules CII
7. Findings from New Study on Occupational Exposure to BPA of Limited Relevance to Consumers
8. Research Findings Key for Understanding, Interpreting Genetic Testing for Long QT Syndrome
9. Contour Products Promotes Survey for National Respiratory Care Week, Findings Prove Benefits of Contour CPAP Pillow for Sleep Apnea Patients
10. New findings on the formation of body pigment
11. Findings about veracity of peripheral vision could lead to better robotic eyes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... October 12, 2017 , ... ... meet the demand of today’s consumer and regulatory authorities worldwide. From Children’s to ... and tested to meet the highest standard. , These products are also: ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical ... Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. ... honor of Morris F. Collen, a pioneer in the field of medical informatics, this ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... drug delivery system that we intend to develop to enable prevention of a ... lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... On Saturday, ... a treadmill relay – Miles by Moonlight to raise money for the American Heart ... or more. , Teams will work together to keep their treadmills moving for ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  True Health, a ... amplified its effort during National Breast Cancer Awareness ... cancer risks. ... Oncology calculated that more than 10 million American ... mutations in BRCA1 or BRCA2 and have not had ...
(Date:10/10/2017)... , Oct. 10, 2017  NDS received FDA 510(k) clearance ... a medical-grade battery-powered display stand specifically designed for endoscopy environments. An ... technology into a clinical solution to support the improvement of patient ... Innovative Design ... Wireless Solution ...
(Date:10/7/2017)... --  Provista, a proven leader in the supply ... power, today announced a new resource area on Provistaco.com ... is the online home for case studies, articles on ... releases, slideshows and events. ... at their fingertips, viewers can also watch short videos ...
Breaking Medicine Technology: