Navigation Links
Appropriate medical screening for antimalarials vital to US military personnel
Date:2/19/2008

Malaria is a constant threat to US military personnel operating in Afghanistan, but some troops may face further risk, as epidemiologists have revealed a significant prevalence of contraindications to the safe use of the anti-malarial drug, mefloquine.

Whilst mefloquine has traditionally been considered an effective prevention for long-term malaria chemoprophylaxis, research reported in the open access publication, Malaria Journal, suggests that US military physicians should ensure careful screening processes prior to prescribing and dispensing the drug. Ignoring such contraindications may lead to an increased incidence of psychiatric and neurological disorders.

An epidemiological study from the US Army Center for Health Promotion and Preventive Medicine, led by Remington Nevin, used military medical surveillance and pharmacosurveillance databases to identify contraindications to mefloquine use among a cohort of 11,725 active duty U.S. military personnel, recently deployed to Afghanistan. The study indicates that 9.6 percent of service members deployed to Afghanistan in early 2007 had evidence of psychiatric, medical or pharmacological contraindications to mefloquine, the primary drug used to protect service members from malaria, which is endemic there. It was also reported that females were twice as likely as males to have a contraindication.

This work underscores the importance of proper systematic screening prior to prescribing and dispensing mefloquine, and the need to provide alternatives to mefloquine suitable for long-term administration among deployed U.S. military personnel.

Mefloquine is generally considered safe when prescribed and dispensed appropriately, and when used as directed. However, this study provides evidence that mefloquine is not a suitable option for a significant number of deploying U.S. servicemembers. This study points to the need for enhanced vigilance during pre-deployment medical screening to ensure the appropriate use of this medication, particularly among females, and underscores the need for continued investment in research and development of alternatives to mefloquine that retain the advantages in compliance of a weekly medication.


'/>"/>

Contact: Charlotte Webber
press@biomedcentral.com
44-020-763-19980
BioMed Central
Source:Eurekalert

Related medicine news :

1. Childhood asthma still inappropriately treated in the UK
2. American Heart Association Surgical Supplement Journal Report: Appropriate Hospital Discharge System Can Prevent Future Cardiac Events
3. Study Finds New Version of QIAGENs HPV Test for Developing Countries Could Reduce Risk of Cervical Cancer by More than Half When Combined With Appropriate Treatment
4. Geriatrician Care Guards Against Risk of Inappropriate Meds
5. Appropriate timing in the use of breast shields in children can further reduce MDCT radiation dose
6. MSU engineering team designs innovative medical device
7. ATS Medical to Present at the 2007 Thomas Weisel Partners Healthcare Conference
8. Providence St. Joseph Medical Center, Caregivers Reach Agreement on a Union Contract
9. Owner and Operator of Florida Durable Medical Equipment Company Convicted of Medicare Fraud
10. Father and Daughter From Tanzania Receive Their First Medical Examination in Newport Beach
11. Doctors and medical ethicist discuss whether doctors should participate in capital punishment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... ... May 03, 2016 , ... California health startup Pegara ... that helps people assess their risk of developing Alzheimer’s disease. Using a questionnaire ... a “Risk Reduction Score™” that summarizes how their lifestyle choices may affect their ...
(Date:5/3/2016)... ... 03, 2016 , ... SELEX (systematic evolution of ligands ... random library of sequences depending on their attraction for a target molecule. These ... is commonly performed using filters, panning, or affinity chromatography separations. However, these traditional ...
(Date:5/3/2016)... ... May 03, 2016 , ... Elizabeth Murray has always loved walking ... her with one on her shoulder and one on her arm. But she got ... of years of mitral valve prolapse. , The valves of the heart wouldn’t close ...
(Date:5/3/2016)... , ... May 03, 2016 , ... ... has been selected by Tidelands Health, a three hospital system in South Carolina, ... constantly on the lookout for technology that enhances communication, drives workflow efficiencies and ...
(Date:5/3/2016)... ... May 03, 2016 , ... Each year, about 800,000 ... of death across the United States and account for one death every four minutes. ... or are permanently disabled. HCR ManorCare is launching a video series called “Your Brain,” ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... NEW YORK , April 28, 2016 /PRNewswire/ ... will notably complement the company,s valve repair and ... the move also places Abbott more firmly into ... one of the fastest growing device areas, with ... to its recent report,  Advanced Remote Patient ...
(Date:4/28/2016)...  Marking its one year anniversary since launching ... risk test, Color Genomics announced a ... impact the most common hereditary cancers affecting both ... analyzes hereditary cancer risks for breast, colorectal, melanoma, ... Color Test is physician ordered and includes genetic ...
(Date:4/28/2016)... , April 28, 2016  The blood testing ... million dollars, according to Kalorama Information and The Freedonia ... immunoassays and nucleic acid testing.  The healthcare research firm ... progress in developing blood collection stations and in improving ... in Kalorama Information,s report, Blood Testing Market ...
Breaking Medicine Technology: