Navigation Links
Apples Help Keep Muscles Strong, Mouse Study Finds
Date:6/9/2011

THURSDAY, June 9 (HealthDay News) -- A natural compound found in apples may help prevent muscle wasting that can result from aging and illness, according to the results of a study in mice.

The benefit appears to come from a compound in apple skin called ursolic acid, according to Dr. Christopher Adams, of the University of Iowa in Iowa City, and colleagues.

Adams and colleagues first identified 63 genes that change in response to fasting in both people and mice, and another 29 that change their expression in the muscles of both people who are fasting and those with spinal cord injuries. They then looked at 1,300 small molecules and zeroed in on ursolic acid as a compound that might counteract muscle atrophy.

In the next phase, the researchers found that ursolic acid could protect against muscle wasting in mice that were deprived of food. They also found that adding ursolic acid to the food of normal mice for a number of weeks prompted muscle growth.

In addition, mice that received ursolic acid became leaner and had lower blood levels of glucose, cholesterol and triglycerides, the investigators found.

The health benefits noted in the mice were due to enhanced insulin signaling in muscle and to corrections in gene signatures associated with muscle atrophy, the researchers explained.

"Ursolic acid is an interesting natural compound," Adams said in a journal news release. "It's part of a normal diet as a component of apple peels. They always say that an apple a day keeps the doctor away....People who eat junk food don't get this."

It is not clear whether the findings in mice will be confirmed in human trials, however, and whether the amount of ursolic acid consumed as part of a normal diet would protect against the ravages of muscle wasting.

The findings, published in the June issue of the journal Cell Metabolism, might lead to the development of new drugs if confirmed in humans, the s
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Apples for me, Doritos for you: Consumers buy healthier foods for themselves
2. Apples Are the New Superfruit
3. Agency Pioneer SVH Tours & Travel Launches AppleSpecials.com, New Travel Booking Web Site that Showcases First-Hand Videos and Last Minute Specials
4. Surgery to repair torn shoulder muscles in the elderly can reduce pain and improve function
5. Brain stimulation can help partially paralyzed stroke patients regain use of their muscles
6. Clenching Muscles May Boost Willpower
7. Teens Breast-fed as Infants Have Stronger Leg Muscles
8. Penguins continue diving long after muscles run out of oxygen
9. Elevated protein levels in cardiac muscles could predict mortality following angioplasty
10. Protein drinks after exercise help maintain aging muscles
11. Tweens Can Take Charge of Their Health with New Book "Be Fit, Be Strong, Be You"
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Apples Help Keep Muscles Strong, Mouse Study Finds
(Date:9/18/2014)... Luis Obispo, CA (PRWEB) September 18, 2014 ... Bootie introduced their newest, patent pending bunion splint to ... As one loyalist, Rosa, wrote: "I was absolutely delighted. It ... I honestly forget I am wearing them. THANK YOU FOR ... recently introduced design by saying, "The hole used to slip ...
(Date:9/18/2014)... HealthDay Reporter , THURSDAY, Sept. ... a common antidepressant can quickly alter the way brain cells ... reported online Sept. 18 in Current Biology , ... widely prescribed antidepressants. Experts said the hope is to eventually ... to benefit from a drug -- and which people would ...
(Date:9/18/2014)... TayganPoint Consulting Group, a leading ... and co-founder John Cassimatis was named as one ... 2014, recognizing the region’s top healthcare and life ... of the year. , The Innovation Awards celebrate ... continue to shape the medical industry in Greater ...
(Date:9/18/2014)... microbes -- don,t worry, it,s a good thing! As ... microbes are bad. Many active enzymes and bacteria are ... as an important part of our digestive system or ... albicans , an opportunistic yeast pathogen and model organism ... healthy personal ecosystem. However, when our immune system is ...
(Date:9/18/2014)... The effect of guidelines recommending that elderly men should ... minimal at best," according to a new study led ... as a research letter online in JAMA Internal ... prostate-specific antigen to test for prostate cancer., "We ... the routine screening of elderly men in particular has ...
Breaking Medicine News(10 mins):Health News:Feedback for the New Bunion Bootie Design Feedback is Already Pouring In, and Bunion Sufferers Love It 2Health News:Feedback for the New Bunion Bootie Design Feedback is Already Pouring In, and Bunion Sufferers Love It 3Health News:One Dose of Antidepressant Changes Brain Connections, Study Says 2Health News:One Dose of Antidepressant Changes Brain Connections, Study Says 3Health News:TayganPoint Executive Receives Prestigious Award from Philadelphia Business Journal 2Health News:Everything in moderation: Micro-8 to study regulating pathogens in space 2Health News:Everything in moderation: Micro-8 to study regulating pathogens in space 3Health News:Professional recommendations against routine prostate cancer screening have little effect 2
... Analytical, based in Ames, IA will reveal the latest results ... system. This instrument rapidly identifies microorganisms in less ... The generated fingerprint when compared to a database of ... strain typing and tracking.Because of its ease of use and ...
... 2009, the United States District Court for the Southern ... previously disclosed antitrust lawsuit filed by Pioneer Valley Casket ... casket retailers against Batesville Casket Company, Inc., a wholly ... )The Pioneer Valley plaintiffs agreed to dismiss their complaint ...
... Inc. (NYSE: DVA ) announced that the United ... has informed the company that it has completed its investigation ... was first issued a formal subpoena in October 2004 and ... against the company, no fines were assessed and no mandatory ...
... A new survey from Noblis Health Innovation, a ... context of the current economic crisis, nearly a third of hospitals ... Conducted in April 2009, the affiliation study is the first in ... Noblis Insights Panel , a collection of more than 150 leading ...
... make that dream so real, goes a popular song. Now ... to perform an essential form of DNA repair. , Prof. ... been studying DNA repair for some two decades: ,Considering that ... a day by radiation, pollutants and harmful chemicals produced within ...
... Cancer Screenings And Education about Skin Cancer PreventionSKILLMAN, N.J., ... Johnson Consumer Companies, Inc., announces its second year of ... Skin" tour. The free skin cancer screening tour ... New York City,s Grand Central Terminal, and will visit ...
Cached Medicine News:Health News:Advanced Analytical Reveals New Platform for Rapid Genotypic Identification of Microorganisms at ASM 2009 2Health News:Federal District Judge Dismisses Antitrust Lawsuit Against Batesville Casket Company 2Health News:Noblis Insights Panel Finds Growing Interest in Hospital Affiliation as a Strategic Response to Challenging Market Conditions 2Health News:Noblis Insights Panel Finds Growing Interest in Hospital Affiliation as a Strategic Response to Challenging Market Conditions 3Health News:Stopgap DNA repair needs a second step 2Health News:AVEENO(R) Announces Kick-Off of The Skin Cancer Foundation's 2nd Annual 'Road to Healthy Skin' Tour Presented by AVEENO(R) and Rite Aid 2Health News:AVEENO(R) Announces Kick-Off of The Skin Cancer Foundation's 2nd Annual 'Road to Healthy Skin' Tour Presented by AVEENO(R) and Rite Aid 3Health News:AVEENO(R) Announces Kick-Off of The Skin Cancer Foundation's 2nd Annual 'Road to Healthy Skin' Tour Presented by AVEENO(R) and Rite Aid 4
(Date:9/18/2014)...  KIYATEC announced today that it has been ... (SBIR) Phase II Contract from the National Cancer ... centers that comprise the National Institutes of Health ... award, KIYATEC will expand its 3D breast cancer ... of cancer therapy strategies: 1) cancer,s interaction with ...
(Date:9/18/2014)... Mass. , Sept. 18, 2014  Decision Resources ... anti-vascular endothelial growth factor (VEGF) agent for wet AMD, ... Medicare Advantage plans as Genentech,s Lucentis, which is the ... surveyed managed care organization (MCO) directors do not identify ... is slightly more likely than Lucentis to be listed ...
(Date:9/18/2014)... Sept. 18, 2014  ePharmaSolutions, the leading ... as the Disruptive Innovator of the Year ... eClinical platform. This solution includes an integrated ... file (eTMF), a remote monitoring application, eSource ... patient screening and matching technology. ...
Breaking Medicine Technology:National Cancer Institute Awards KIYATEC Nearly $2M to Advance Predictive Cancer Diagnostics 2National Cancer Institute Awards KIYATEC Nearly $2M to Advance Predictive Cancer Diagnostics 3Regeneron's Eylea and Genentech's Lucentis Are Equally Likely to be Covered on Commercial and Medicare Advantage Plans for Wet AMD 2Regeneron's Eylea and Genentech's Lucentis Are Equally Likely to be Covered on Commercial and Medicare Advantage Plans for Wet AMD 3ePharmaSolutions Named 2014 Disruptive Innovator of the Year for its ePharmaONE eClinical Platform 2ePharmaSolutions Named 2014 Disruptive Innovator of the Year for its ePharmaONE eClinical Platform 3
... YORK, Dec. 8, 2010 Reportlinker.com announces that ... its catalogue: Asia-Pacific Dental Devices ... http://www.reportlinker.com/p0336613/Asia-Pacific-Dental-Devices-Market-Outlook-to-2016.html Asia-Pacific Dental Devices ... new report, "Asia-Pacific Dental Devices Market Outlook to ...
... 2010 Reportlinker.com announces that a new market research ... China Pharmaceutical Market Overview http://www.reportlinker.com/p0337367/China-Pharmaceutical-Market-Overview.html ... pharma market generated sales of $22.9 billion in 2009, ... and 2009. Key growth drivers include China,s support of ...
Cached Medicine Technology:Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 2Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 3Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 4Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 5Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 6Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 7Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 8Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 9Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 10Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 11Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 12Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 13Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 14Reportlinker Adds Asia-Pacific Dental Devices Market Outlook to 2016 15Reportlinker Adds China Pharmaceutical Market Overview 2Reportlinker Adds China Pharmaceutical Market Overview 3Reportlinker Adds China Pharmaceutical Market Overview 4Reportlinker Adds China Pharmaceutical Market Overview 5Reportlinker Adds China Pharmaceutical Market Overview 6Reportlinker Adds China Pharmaceutical Market Overview 7Reportlinker Adds China Pharmaceutical Market Overview 8Reportlinker Adds China Pharmaceutical Market Overview 9Reportlinker Adds China Pharmaceutical Market Overview 10Reportlinker Adds China Pharmaceutical Market Overview 11Reportlinker Adds China Pharmaceutical Market Overview 12Reportlinker Adds China Pharmaceutical Market Overview 13Reportlinker Adds China Pharmaceutical Market Overview 14Reportlinker Adds China Pharmaceutical Market Overview 15Reportlinker Adds China Pharmaceutical Market Overview 16Reportlinker Adds China Pharmaceutical Market Overview 17
Span Diagnostics Limited...
Malaria ( P. Falciparum ) Whole Blood Strip / Cassette...
DiaMed OptiMAL-IT is an immuno-chromatographic test, using monoclonal antibodies against the metabolic enzyme pLDH (parasite lactate dehydrogenase) of Plasmodium spp. These Mabs are classified in t...
Core Malaria Pf is a rapid self performing, qualitative, two site sandwich immunoassay for the determination of P. falciparum specific histidine rich protein 2 (Pf HRP-2) in whole blood samples...
Medicine Products: