Navigation Links
Appealing the death sentence for brain cells
Date:5/29/2008

etermined a small portion of the protein (NAP) provides potent neuroprotection by protecting nerve cells against severe oxidative stress and the toxicity associated with diseases such as Alzheimer's. AL-108, the drug candidate under development now, is an intranasal formulation based on NAP.

What happens in the nerve cells of Alzheimer's brains can be likened to a derailed train, says Prof. Gozes. The nerve cell skeleton the microtubules are like the rails, and a protein called "tau" functions like the ties between the rails. In Alzheimer's, the ties fall off, the tracks fall apart and nerve cells die. AL-108 however, seems to prevent this process from accelerating.

AL-108, which could be ready in as early as 5 years, targets the microtubules and protects against amyloid plaques a characteristic of Alzheimer's disease. AL-108 also seems to be able to maintain brain microtubule functioning, preventing memory loss and the deterioration of other cognitive functions, such as learning abilities, in those whose mental functioning has already started to decline.

"It's important to stress that these are drug candidates in clinical development in North America for now, and will not be ready for several years," says Prof. Gozes, who co-founded Allon Therapeutics with Tel Aviv University's technology transfer arm Ramot.


'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. World Vision Appealing for $2 Million for Deadly China Quake
2. Exercise cuts cancer death in men
3. Air Bags-Seat Belts Cut Injuries, Deaths, Costs
4. Educational Drive Cut Death Rate From Sepsis
5. Men at increased risk of death from pneumonia compared to women
6. Hidden heart condition increases the risk of death in patients waiting for kidney transplants
7. Biomarkers Predict Heart Deaths
8. Death Gap Widens Between Educated and Those Not
9. Boston Scientific Announces FDA Approval for New Devices to Treat Heart Failure and Sudden Cardiac Death
10. Beta Blockers Raise Stroke, Death Risk After Surgery
11. Metoprolol around the time of surgery increases the risk of death and stroke: POISE trial
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Appealing the death sentence for brain cells
(Date:8/31/2015)... ... August 31, 2015 , ... The ... on the use of health IT to create efficiencies in healthcare information exchange, ... 2015 . Taking place at the Hyatt Regency Reston in Reston, Va. from ...
(Date:8/31/2015)... ... August 31, 2015 , ... It’s a lot like ... director of GreenFields of Geneva. During his first days on the job, he’s run ... nice seeing them, and I like knowing that they’re living in such a wonderful ...
(Date:8/31/2015)... ... August 31, 2015 , ... The Brooks Group, a global ... a department devoted to helping organizations identify and keep the best talent both ... The Brooks Group believes in offering a solution that goes beyond simply providing ...
(Date:8/31/2015)... ... August 31, 2015 , ... PartnerTech ... Business Owners and provided a tour of their North American facility following the ... to international companies expanding business in the U.S. , The PartnerTech Inc. ...
(Date:8/31/2015)... (PRWEB) , ... August 31, 2015 , ... According to ... Cancer Solution: Taking Charge of Your Life with Cancer is an excellent resource ... Santangeloon found The Cancer Solution to be helpful in explaining what cancer is in ...
Breaking Medicine News(10 mins):Health News:WEDI Announces Program for Annual Fall Conference: WEDI-Con 2015 2Health News:WEDI Announces Program for Annual Fall Conference: WEDI-Con 2015 3Health News:Friendship Senior Options Welcomes New Executive Director for GreenFields of Geneva 2Health News:The Brooks Group Introduces Talent Management Division 2Health News:The Brooks Group Introduces Talent Management Division 3Health News:PartnerTech Supports Economic Growth as Host 2Health News:New Book The Cancer Solution Is a Must Read for Everyone Affected by Cancer 2
... education bill in the state that allows private professional colleges ... ,Lok Sabha member Panniyan Ravindran, while talking to the Gulf ... said he would fight it. ,He was in ... anniversary of Kerala's former chief minister P.K. Vasudevan Nair. ...
... Bhopal and two of its doctors have been asked by ... for alleged// post-operative negligence resulting in the death of a ... Ayushman Hospital following swelling in her uterus and respiratory trouble. ... Since the tumor was not malignant and the possibility of ...
... Health Organization has communicated to countries the benefits of building ... 100 companies have sent in their request// to Roche AG, ... to combat a potential bird-flu pandemic. ,Though ... flu, yet they have enabled companies a list of things ...
... Health Canada has warned about the inherent risks involved ... ,The human milk is capable of ... There are chances that the human milk carries remnants ... consumed. Even unhygienic storage of milk, and not adhering ...
... care workers in the United States has risen, so ... ,According to Vanderbilt infectious disease experts Timothy ... should be provided to health care workers with latent ... test, particularly if they meet certain high-risk criteria. ...
... Pharma company Venus Remedies Ltd today said it ... its latest antibiotic fixed dose combination used in ... ,The new antibiotic combination, active against multi-resistant strains ... provides a broad-spectrum coverage of bactericidal activity, it ...
Cached Medicine News:
(Date:8/28/2015)... HILL, N.C. , Aug. 28, 2015 /PRNewswire/ ... market research projects can slow down the decision-making ... It is, therefore, absolutely critical for biopharmaceutical companies ... market research approval process for quicker and more ... research by Best Practices, LLC, nearly three-quarters of ...
(Date:8/28/2015)... , Aug. 28, 2015 ... has announced the addition of the "Investigation ... to their offering. Originally discovered by ... Yoshitomi Pharmaceutical Industries, Ltd) as an inflammatory drug, ... Senju Pharmaceutical Co., Ltd under the trade name ...
(Date:8/28/2015)... DUBLIN , Aug. 28, 2015 ... announced the addition of the "Investigation Report on ... Tobramycin is a traditional antibiotic whose eye ... for the treatment of potential infection or inflammation caused ... China are able to produce tobramycin, ...
Breaking Medicine Technology:Expediting the Pharmaceutical Market Research Process for Faster Insights 2Investigation Report on China's Pranoprofen Market, 2010-2019 2Investigation Report on China's Tobramycin Market, 2015-2019 2
... UPI ) announced today that it will release financial ... at the market close on Monday, November 2, 2009. ... results on Monday, November 2, 2009 at 3:30 p.m. Central ... Medi Jiwani, Vice President, Chief Financial Officer and Treasurer, will ...
... 21 Shire plc,(LSE: SHP, NASDAQ: SHPGY ), ... Biologics License Application (BLA) with the U.S.,Food and Drug ... for Fabry disease, by the end of the year. ... filed at the,request of FDA, has been approved, and ...
Cached Medicine Technology:Uroplasty to Issue Second Fiscal Quarter Results on November 2, 2009 2Shire Targets Fourth Quarter Filing of BLA for REPLAGAL(R) for Fabry Disease With U.S. FDA 2Shire Targets Fourth Quarter Filing of BLA for REPLAGAL(R) for Fabry Disease With U.S. FDA 3Shire Targets Fourth Quarter Filing of BLA for REPLAGAL(R) for Fabry Disease With U.S. FDA 4
VACUETTE® Tube Holders should be used exclusively with VACUETTE® Blood Collection Needles as both components are designed for optimal compatibility with one another....
The Optima III 45 cm line of laparoscopic hand instruments is ideal for operative laparoscopic/endoscopic procedures or when a longer instrument is needed....
Less traumatic jaws offer a firm grasp while a self-retaining spring maintains hold on the needle. Use for grasping, applying endoloops, and driving needles during extracorporeal suturing....
The Optima III 45 cm line of laparoscopic hand instruments is ideal for operative laparoscopic/endoscopic procedures or when a longer instrument is needed....
Medicine Products: