Navigation Links
Antiviral therapy may prevent liver cancer in hepatitis B patients
Date:6/9/2014

DETROIT Researchers have found that antiviral therapy may be successful in preventing hepatitis B virus from developing into the most common form of liver cancer, hepatocellular carcinoma (HCC).

That was the finding of a study published in the May issue of Clinical Gastroenterology and Hepatology. Investigators from Henry Ford Health System in Detroit, Geisinger Health System in Danville, Pa., and Kaiser Permanente in Honolulu, Hawaii and Portland, Ore. participated in the study, along with investigators from the Centers for Disease Control and Prevention in Atlanta.

According to the first-of-its-kind analysis of more than 2,600 adult participants with hepatitis B, those treated with antiviral therapy had a significantly lower occurrence of HCC during a five-year follow up period. Overall, 3 percent of patients developed HCC during the study's timeframe. But patients who received antiviral therapy were 60 percent less likely to develop HCC than untreated patients.

"The results of this study allow us to reassure our patients that we are not just treating their viral levels, but that antiviral therapy may actually lessen their chance of developing liver cancer," said the study's lead investigator, Henry Ford Health System's Stuart C. Gordon, M.D., who worked closely with Henry Ford Senior Scientist Mei Lu in Detroit.

HCC accounts for the most liver cancers in the United States, typically occurs in people age 50 or older and is more common in men. If the cancer cannot be removed, it is usually fatal in three to six months. In most cases, HCC is caused by scarring in the liver cirrhosis which can be a result of alcohol abuse, hepatitis B or C, chronic inflammation of the liver or an iron overload.

"This study was one of the first to address antiviral therapy and its efficacy in preventing hepatitis B from developing into liver cancer," said Joseph Boscarino, Ph.D., senior scientist and investigator for the Geisinger site. "With this information, clinicians can begin to prescribe antiviral therapy for hepatitis B patients with the goal of preventing a common and dangerous form of cancer."


'/>"/>

Contact: Tammy Battaglia
Tammy.Battaglia@hfhs.org
248-881-0809
Henry Ford Health System
Source:Eurekalert  

Related medicine news :

1. CONRAD to host HIV symposium at 2nd Annual Antivirals Congress
2. Antiviral Therapy May Cut Recurrence of Hepatitis B-Linked Liver Cancer
3. Adult antiviral drug effective in suppressing hepatitis B in teens
4. Researchers developing antiviral drug to combat contagious norovirus
5. Direct-acting antivirals now ready for prime time
6. Genetics of cervical cancer raise concern about antiviral therapy in some cases
7. Hemorrhagic fevers can be caused by bodys antiviral interferon response
8. KRAS gene mutation and amplification status affects sensitivity to antifolate therapy
9. Antibody therapy prevents gastrointestinal damage following radiation exposure in mice
10. Chemotherapy proves life-saving for some leukemia patients who fail induction therapy
11. Immunotherapy for elderly cancer patients finds new promise in drug combination
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antiviral therapy may prevent liver cancer in hepatitis B patients
(Date:4/25/2017)... ... April 25, 2017 , ... Coalition ... for Duchenne muscular dystrophy, and funding for Duchenne research, congratulates Capricor Therapeutics ... HOPE clinical trial in Duchenne announced today. , Coalition Duchenne funded studies ...
(Date:4/25/2017)... Boulder, CO (PRWEB) , ... April 25, 2017 ... ... Law and Liberty attempts to compare student test score performance for the 2015-16 ... one of the state’s voucher programs. Though it highlights important patterns in student ...
(Date:4/25/2017)... ... April 25, 2017 , ... Patients who ... achieves results in a fraction of the time as traditional braces – Wilckodontics®. ... Dental Specialists, now offers this revolutionary treatment with or without a referral. ...
(Date:4/25/2017)... ... April 25, 2017 , ... Back Pain Centers of America (BPC), ... reputable physician in their area, announces the launch of a new and proprietary customer ... are looking for reputable physicians to help them with back or neck pain and ...
(Date:4/25/2017)... , ... April 25, 2017 , ... ... of predictive analytics to its patient care management module. Using this new feature, ... a patient has been initiated on continuous positive airway pressure (CPAP), oral, or ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... , April 19, 2017  Sorrento Therapeutics, Inc. ... clinical-stage biopharmaceutical company developing new treatments for cancer ... closing of its previously announced underwritten public offering ... a public offering price of $2.00 per share, ... offering expenses payable by Sorrento.  The net proceeds ...
(Date:4/19/2017)... Calif. , April 19, 2017  SARES•REGIS ... buildings it is developing at Conejo Spectrum Business ... , to Atara Biotherapeutics, Inc. , a ... severe and life-threatening diseases that have been underserved ... allogeneic T-cell therapies for cancer, autoimmune and infectious ...
(Date:4/18/2017)... -- Research and Markets has announced the addition of ... offering. ... market to grow at a CAGR of 6.35% during the period ... has been prepared based on an in-depth market analysis with inputs ... growth prospects over the coming years. The report also includes a ...
Breaking Medicine Technology: