Navigation Links
Antiviral therapy may prevent liver cancer in hepatitis B patients
Date:6/9/2014

DETROIT Researchers have found that antiviral therapy may be successful in preventing hepatitis B virus from developing into the most common form of liver cancer, hepatocellular carcinoma (HCC).

That was the finding of a study published in the May issue of Clinical Gastroenterology and Hepatology. Investigators from Henry Ford Health System in Detroit, Geisinger Health System in Danville, Pa., and Kaiser Permanente in Honolulu, Hawaii and Portland, Ore. participated in the study, along with investigators from the Centers for Disease Control and Prevention in Atlanta.

According to the first-of-its-kind analysis of more than 2,600 adult participants with hepatitis B, those treated with antiviral therapy had a significantly lower occurrence of HCC during a five-year follow up period. Overall, 3 percent of patients developed HCC during the study's timeframe. But patients who received antiviral therapy were 60 percent less likely to develop HCC than untreated patients.

"The results of this study allow us to reassure our patients that we are not just treating their viral levels, but that antiviral therapy may actually lessen their chance of developing liver cancer," said the study's lead investigator, Henry Ford Health System's Stuart C. Gordon, M.D., who worked closely with Henry Ford Senior Scientist Mei Lu in Detroit.

HCC accounts for the most liver cancers in the United States, typically occurs in people age 50 or older and is more common in men. If the cancer cannot be removed, it is usually fatal in three to six months. In most cases, HCC is caused by scarring in the liver cirrhosis which can be a result of alcohol abuse, hepatitis B or C, chronic inflammation of the liver or an iron overload.

"This study was one of the first to address antiviral therapy and its efficacy in preventing hepatitis B from developing into liver cancer," said Joseph Boscarino, Ph.D., senior scientist and investigator for the Geisinger site. "With this information, clinicians can begin to prescribe antiviral therapy for hepatitis B patients with the goal of preventing a common and dangerous form of cancer."


'/>"/>

Contact: Tammy Battaglia
Tammy.Battaglia@hfhs.org
248-881-0809
Henry Ford Health System
Source:Eurekalert  

Related medicine news :

1. CONRAD to host HIV symposium at 2nd Annual Antivirals Congress
2. Antiviral Therapy May Cut Recurrence of Hepatitis B-Linked Liver Cancer
3. Adult antiviral drug effective in suppressing hepatitis B in teens
4. Researchers developing antiviral drug to combat contagious norovirus
5. Direct-acting antivirals now ready for prime time
6. Genetics of cervical cancer raise concern about antiviral therapy in some cases
7. Hemorrhagic fevers can be caused by bodys antiviral interferon response
8. KRAS gene mutation and amplification status affects sensitivity to antifolate therapy
9. Antibody therapy prevents gastrointestinal damage following radiation exposure in mice
10. Chemotherapy proves life-saving for some leukemia patients who fail induction therapy
11. Immunotherapy for elderly cancer patients finds new promise in drug combination
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antiviral therapy may prevent liver cancer in hepatitis B patients
(Date:5/27/2016)... ... May 27, 2016 , ... Beleza Medspa has initiated ... regulations. This is the first time that Coolsculpting is being used for for ... six months to ensure they meet the prescribed body-fat standard, measured by the circumference-based ...
(Date:5/27/2016)... ... , ... With a team of certified experts, Validation Center ... its GMP accreditation, Validation Center is also a registered authority of the international ... , Validation Center is ISO17025 accredited and only offers its clients the latest ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... thousands of defective respirators, according to court documents and SEC filings. A ... and Becky Tyler v. American Optical Corporation, Case No. BC588866, Los Angeles County, ...
(Date:5/26/2016)... ... May 26, 2016 , ... On Memorial Day, Hope For Heroes ... in military battle for the country. The nonprofit Hope For Heroes partnered with ... that empower independence for disabled military veterans, as well as police, firemen, and EMS ...
(Date:5/26/2016)... ... , ... MadgeTech will be showcasing its line of data logging products ... the MadgeTech headquarters. With products sold in more than 100 countries around the world, ... , In 2012, NASA strategically set up 17 RHTemp101A MadgeTech data loggers ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... 24, 2016 Niederländische Chirurgen ... die es Ärzten erlaubt, ihre Expertise weltweit zu ... kombiniert Live Streaming mit einer Instant-Messaging-Funktion und der ... Mediziner in Europa, Afrika, Asien und den ... die Plattform registriert. Information und Weiterbildung   ...
(Date:5/24/2016)... , May 24, 2016  Diana Russell suffers from ... organs from the inside out.  This disease has put ... on her children and grandchildren to leave her home.  ... Diana,s family cannot haul the wheelchair.  So if there ... car, and Diana is left to wait for the ...
(Date:5/24/2016)... -- Joe Marziani has joined VMS BioMarketing as senior vice president of sales, announced ... role, Marziani will lead the company,s business development and sales team, exploring new opportunities ... Photo - http://photos.prnewswire.com/prnh/20160523/371089 ... ... ...
Breaking Medicine Technology: