Navigation Links
Antiretroviral treatment for HIV reduces food insecurity, reports AIDS Journal

Philadelphia, Pa. (December 4, 2012) Can treatment with modern anti-HIV drugs help fight hunger for HIV-infected patients in Africa? Starting antiretroviral therapy for HIV reduces "food insecurity" among patients in Uganda, suggests a study published online by the journal AIDS, official journal of the International AIDS Society. AIDS is published by Lippincott Williams & Wilkins, a part ofWolters Kluwer Health.


Treatment including antiretroviral therapy (ART) may lead to a "positive feedback loop" whereby improved functioning and productivity lead to increased ability to workand thus to decreased food insecurity, according to the study by Kartika Palar, PhD and colleagues of University of California Los Angeles and RAND Corporation. The article is available on the AIDS journal homepage and in the November 28 print edition.

Food Insecurity Decreases in Year after Starting ART

The researchers studied 602 patients receiving first-time care for HIV disease at two clinics in Uganda. At one clinic, patients were started on ART, the most effective drug treatment for HIV. Patients at the other clinic were close to becoming eligible but not yet started on ART.

During the first year of treatment, the two groups were compared for changes in their level of food insecurity, defined as "the limited or uncertain availability of adequate food." Based on a simple questionnaire, about half of patients had severe food insecurity at the start of treatment (53 percent in the ART group and 46 percent of those not receiving ART).

In both groups, starting HIV treatment led to improved food security. However, the trend was more pronounced in the group receiving ART. By twelve months, the rate of severe food insecurity had decreased to 13 percent of the ART group versus 18 percent in the non-ART group.

Examination of other variables gave insight into the "pathway" by which ART may lead to improved food security. Patients starting antiretroviral drugs had greater improvements in work status and in mental healthparticularly decreased scores for depression. Although physical health also improved during treatmentwith or without ARTthis did not seem to contribute to the reduction in food insecurity.

Changing the 'Vicious Cycle' to an 'Upward Spiral'

Researchers are just beginning to explore the socioeconomic and psychological benefits of ART for HIV-infected patients. In developing countries such as Uganda, food insecurity is a common problem with important effects on health. Previous studies have shown that patients with food insecurity are less likely to follow up with recommended treatment for HIV and have poorer treatment outcomes.

The new study provides evidence that starting treatment for HIVespecially treatment including ARTleads to improved food security. The reductions in food insecurity were achieved even though neither of the study clinics offered food assistance.

"Our results suggest that greater ability to work and reduced symptoms of depression may be the primary pathways through which ART improves food insecurity," Dr Palar and coauthors write. They suggest a "bidirectional relationship" between ART and food insecurity.

While ART alone can't solve the problem of food insecurity, the researchers believe that policymakers should consider interventions to halt the "vicious cycle" by which HIV leads to worsening social and economic outcomes. Dr Palar and colleagues conclude, "Well-integrated and implemented interventions in the context of comprehensive care have the potential to produce an 'upward spiral' where food security and ART can mutually reinforce each other for the benefit of all those in treatment."

Contact: Connie Hughes
Wolters Kluwer Health

Related medicine news :

1. Antiretroviral treatment for preventing HIV infection: an evidence review for physicians
2. DNDi and Cipla to develop 4-in-1 pediatric antiretroviral drug combination
3. Among new HIV treatment recommendations, all adult patients should be offered antiretroviral therapy
4. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
5. Clinical insight improves treatment with new lung cancer drug
6. Rapid Asthma Treatment in ER May Prevent Admission
7. Novel compound demonstrates anti-leukemic effect in zebrafish, shows promise for human treatment
8. Breast cancer patients suffer treatment-related side effects long after completing care
9. Mayo Clinic offers newly approved treatment for acid reflux disease
10. Mobile Stroke Units Might Trim Time to Treatment
11. Breast Cancer Treatment Side Effects May Last for Years
Post Your Comments:
(Date:11/27/2015)... CA (PRWEB) , ... November 27, 2015 , ... According ... carried out by the University of Toronto and the University of British Columbia suggested ... hospitalizations for head injuries. The article explains that part of the reason for the ...
(Date:11/27/2015)... ... November 27, 2015 , ... An inventor, from Hopkinsville, ... prescription medications at home, so he invented the patent-pending ELECTRONIC M.D. , The ... medications. In doing so, it could help to prevent potential overdose situations. As ...
(Date:11/27/2015)... Aliso Viejo, CA (PRWEB) , ... November 27, 2015 , ... ... exclusively for use in Final Cut Pro X. With ProSidebar: Fasion, video editors ... banners, or use ProSidebar as a minimalist title opener. Utilize presets featuring self-animating ...
(Date:11/27/2015)... ... November 27, 2015 , ... A simply groundbreaking television series, ... interesting show that delves into an array of issues that are presently affecting Americans. ... from open dialogue, this show is changing the subjects consumers focus on, one episode ...
(Date:11/27/2015)... , ... November 27, 2015 , ... ... largest, most successful and prominent nonprofit healthcare organizations in the country. They have ... with various organizations, and helped advance the healthcare industry as a whole through ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... , Nov. 26, 2015  The total global healthcare ... 7% over 2015-2016. Latin America has ... , (excluding Japan ), is second ... continues to face increased healthcare expenditure. In 2013-2014, total ... declined from 43.5% in 2008-2009 to 41.2% in 2013-2014. In ...
(Date:11/25/2015)...  Linden Care, LLC, a retail specialty pharmacy focused ... suffering from chronic pain, said today that it is ... (TRO) enjoining Express Scripts from unilaterally terminating the Pharmacy ... --> --> The company said that ... --> --> In ...
(Date:11/25/2015)... Nov. 25, 2015  ARKRAY USA ... to provide evidence demonstrating the accuracy of its blood ... on Insulin Resistance, Diabetes and Cardiovascular Disease in ... the Company,s GLUCOCARD ® 01 meter and the ... requirements. The ability to accurately measure glucose levels in ...
Breaking Medicine Technology: