Navigation Links
Antipsychotics Linked to Lower Brain Volume in Schizophrenia Patients
Date:7/18/2014

FRIDAY, July 18, 2014 (HealthDay News) -- Antipsychotic drugs are associated with a slight decrease in both brain cells and connections between brain cells in schizophrenia patients, a new study indicates.

However, this loss of what is called brain volume does not worsen schizophrenia symptoms or affect overall mental function, researchers reported in the study published online July 18 in the journal PLoS One.

"It's important to stress that the loss of brain volume doesn't appear to have any effect on people over the nine-year follow-up we conducted, and patients should not stop their medication on the basis of this research," study author Dr. Graham Murray, of the Behavioral and Clinical Neuroscience Institute and the department of psychiatry at the University of Cambridge in England, said in a university news release.

"A key question in future will be to examine whether there is any effect of this loss of brain volume later in life. We need more research in larger studies with longer follow-ups to evaluate the significance of these brain changes," he added.

All people naturally lose some brain volume as they age, but schizophrenia patients lose brain volume at a faster rate. The reasons for this difference aren't known, but it's been suggested that the antipsychotic medications taken by schizophrenia patients may be a factor.

This study included 33 schizophrenia patients and a "control" group of 71 people without the disorder who had a series of brain scans over nine years, from ages 34 to 43. The schizophrenia patients lost 0.7 percent of brain volume a year, compared with 0.5 percent among those in the control group, the findings showed.

The rate of brain volume loss among schizophrenia patients was greater when their dose of antipsychotic medication was higher, the investigators found. However, this association does not prove that the medications actually caused this loss of brain volume.

The researchers also examined, but found no evidence of, any link between the amount of brain volume loss and the severity of schizophrenia symptoms or reduced mental function.

More information

The U.S. National Institute of Mental Health has more about schizophrenia.

SOURCE: University of Cambridge, news release, July 18, 2014

--


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Antipsychotics Do Help Many With Schizophrenia, Study Finds
2. More Kids Taking Antipsychotics for ADHD: Study
3. Older Antipsychotics May Work as Well as Newer Ones: Review
4. More U.S. Kids Prescribed Off-Label Antipsychotics: Study
5. Schizophrenia Patients Who Take Antipsychotics Live Longer, Study Says
6. Long-Term Use of Some Antipsychotics Not Warranted in Older Adults: Study
7. Stroke risk in elderly treated with antipsychotics is newly linked to specific drug actions
8. Antibiotics Linked to Retinal Detachment Risk
9. Pesticides May Be Linked to Slightly Smaller Babies, Shorter Pregnancies
10. Pharmacy Robots Linked to Bacterial Contamination of Drugs
11. 2 genetic deletions in human genome linked to the development of aggressive prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antipsychotics Linked to Lower Brain Volume in Schizophrenia Patients
(Date:1/24/2017)... , ... January 24, 2017 , ... ... visualize, detect, and eliminate cyber threats in real-time, today announced a strategic partnership ... will enable customers to monitor, respond and protect their critical information assets and ...
(Date:1/24/2017)... ... ... His message has been heard by more than 100,000 students and adults across ... Feldman, has reached his biggest national audience yet: the three million daily readers of ... circulation in the country, and he hopes it will help spread his message and ...
(Date:1/24/2017)... ... January 24, 2017 , ... This Saturday, January 28, the BCFA ... very special performance by Alabama Symphony Orchestra musicians Yifan Zhou, Mara McClain & Sarah ... dim sum, and exhibitors offer a look at Chinese games, crafts & more. Festivities ...
(Date:1/24/2017)... Boston, MA (PRWEB) , ... January 24, 2017 ... ... What They Really Need to Thrive , Well-meaning studies such as the Fordham ... and schools can better serve top students, such as including gifted or high-achieving ...
(Date:1/24/2017)... ... January 24, 2017 , ... Date aired: ... , Sharon Kleyne, the nation’s foremost water advocate and host of the nationally ... Health on Voice America, once again welcomed one of her favorite guests and ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... , Jan. 23, 2017  HOPE BIOSCIENCES announced ... to develop and commercialize nuc -gemcitabine™ (APTA-12/HOPE-888) ... Korean pharmaceutical company. nuc -Gemcitabine ... against surface nucleolin found on many cancer cells, ... ADCs (antibody drug conjugates) or SMDCs (small molecule ...
(Date:1/23/2017)... ROCKVILLE, Md. , Jan. 23, 2017 /PRNewswire/ ... to advancing a new standard in respiratory care, ... Committee for Orphan Medicinal Products has granted Orphan ... the treatment of Bronchiolitis Obliterans Syndrome (BOS).  ... Drug Designation from the EMA to treat patients ...
(Date:1/23/2017)... Jan. 23, 2017  Based on its recent ... Sullivan recognizes Ansell, a global leader in protection ... Company of the Year Award. Ansell,s comprehensive product ... wide global footprint have placed it in a ... market. The Company,s established product line and robust ...
Breaking Medicine Technology: