Navigation Links
Antipsychotic Drugs of Little Benefit to Alzheimer's Patients

They offered some relief, but results were not statistically significant

WEDNESDAY, April 2 (HealthDay News) -- The continuing use of antipsychotic drugs provides no cognitive or neuropsychiatric benefit for Alzheimer's patients, a British study concludes.

Researchers at King's College Hospital in London studied 165 patients who were already being treated with antipsychotic drugs. The patients were divided into two groups -- one continued treatment with the drugs, while the other group stopped treatment.

The patients were assessed six and 12 months later, and the researchers found no differences between the two groups in terms of cognitive decline or in the number of neuropsychiatric problems.

Patients with severe neuropsychiatric problems at the start of the study may have derived some benefit from continued drug therapy, but this difference was not statistically significant, the researchers said.

While these findings suggest that continued use of antipsychotic drugs offers no benefits for Alzheimer's patients, this was a small study, the study authors noted. More research is needed to improve management of these patients, they added.

The study appears in the cuurent issue of PLoS Medicine.

Almost all older dementia patients have some neuropsychiatric symptoms, such as agitation, aggression and psychosis. Antipsychotics are often used to manage or control these symptoms, but there are safety concerns, including increased risk of stroke, sedation, edema, chest infections and parkinsonism. Prolonged use of antipsychotics may also lead to a worsening of cognitive decline.

More information

The U.S. National Institute on Aging has more about Alzheimer's medications.

-- Robert Preidt

SOURCE: Public Library of Science, news release, March 31, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Comparison of antipsychotic treatments in adolescents with schizophrenia
2. Weight gain induced by antipsychotic drugs can be avoided
3. Some antipsychotic drugs may be missing their mark
4. Antidepressant as Good as Antipsychotics for Dementia
5. Investigational Agent Targeting Metabotropic Glutamate 2/3 Receptors Demonstrates Antipsychotic Activity in Humans, Study in Nature Medicine Finds
6. HIV Drugs Linked to Increased Risk of Heart Attack
7. China Nepstar Chain Drugstore to Accept TransCard at Shenzhen Outlets
8. New study finds glamorization of drugs in rap music jumped dramatically over 2 decades
9. Two Drugs Better Than One for High Blood Pressure
10. Medco Partners to Develop Patient-Safety System for Prescription Drugs in Sweden
11. Anticoagulant Drugs Had Similar Outcomes After Angioplasty
Post Your Comments:
Related Image:
Antipsychotic Drugs of Little Benefit to Alzheimer's Patients
(Date:10/12/2015)... Carolina (PRWEB) , ... October 12, 2015 , ... Kevin Costello, winner of the “Check-In ... Carolina , embarks today for his dream vacation to Hawaii. , “I didn’t believe I ... out,” he says. “This contest encouraged me to get to the gym and invest in ...
(Date:10/12/2015)... ... October 12, 2015 , ... Amerec , a ... of spa and skin care equipment, will be displaying custom sauna and steam room ... With many high-end resorts and spas as customers, SpaEquip is recognized for their ability ...
(Date:10/12/2015)... ... October 12, 2015 , ... The ... by individuals who lack professional education and clinical training in a health care ... a variety of purposes such as: losing weight, managing pain, or stopping smoking, ...
(Date:10/12/2015)... ... ... American Family Care (AFC), the nation’s leading provider of urgent care and ... Located at 606A Boll Weevil Circle in Enterprise, it is the company’s ninth location ... quality health care accessible and economical with the opening of our medical center in ...
(Date:10/12/2015)... ... 12, 2015 , ... At first glance, it looks like a mini parachute ... a drink in a tiki bar. But the Parachute® Ventricular Partitioning Device being implanted ... (AGH) could potentially signal a new way of treating people with heart failure. , ...
Breaking Medicine News(10 mins):
(Date:10/12/2015)... Oct. 12, 2015 A new computer program ... can predict whether they will develop effective language skills ... a study in the journal Brain and Behavior ... In the journal,s Oct. 12 online edition, researchers ... program determines how specific regions of the brain respond ...
(Date:10/12/2015)... Oct. 12 2015 ... of the "Personalized Medicine, Targeted Therapeutics ... Strategic Analysis of Industry Trends, Technologies, Participants, ... --> ) has announced ... Targeted Therapeutics and Companion Diagnostic Market to ...
(Date:10/12/2015)... , Oct. 12, 2015  Edwards Lifesciences Corporation (NYSE: ... valves and hemodynamic monitoring, plans to announce its operating results ... closes on Monday, October 26, 2015, and will host a ... those results. . A live stream and ... downloading Edwards, IR App for iPhone and iPad ...
Breaking Medicine Technology: