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Antipsychotic Drugs Linked to Higher Odds for Diabetes in Pregnancy
Date:7/2/2012

n of the department of psychiatry at Lenox Hill Hospital in New York City.

"The peak age of onset of schizophrenia in women is 25 to 35 years old, which are also the peak childbearing years," he said. "Women with psychotic illnesses are likely to have more unplanned pregnancies than women without a psychotic illness."

"Obviously, if a patient can do without the medication, it would be appropriate to discontinue it," Bruno said. "But this is frequently not the case, and these decisions have to be made on a case-by-case basis weighing the relative risks versus benefits."

"With limited research data on the impact of newer atypical antipsychotics during pregnancy, pregnant women with bipolar disorder or schizophrenia may be better off with the older antipsychotics," he added. He said the reproductive-safety data on older antipsychotics is more robust and reassuring than it is for newer drugs.

More information

For more on pregnancy, head to the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCES: Bryan Bruno, M.D., acting chairman, department of psychiatry, Lenox Hill Hospital, New York City; July 2, 2012, news release, Archives of General Psychiatry


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