Navigation Links
Antioxidants may help prevent malaria complicaton that leads to learning impairment
Date:6/25/2010

venting neurologic and cognitive impairment."

Zimmerman and colleagues in Brazil studied the persistence of cognitive damage in mice with documented cerebral malaria after cure of the acute parasitic disease with chloroquine, an antimalarial therapy. By administering a battery of behavioral tests to these mice, post-doctoral fellow Patricia Reis, Ph.D., determined that impairment in memory skills was still present 30 days after the initial malaria infection. Cognitive deficits that persist for years after the episode of cerebral malaria have also been reported in 11 percent to 28 percent of children who survive the infection.

"Although we believe that long-term cognitive dysfunction after cerebral malaria is initiated by injury to the brain during the initial period of untreated infection, it is possible that the mechanisms for persistent cognitive deficits are independent of those that cause neurological injury and death during acute cerebral malaria," says Zimmerman. "Future research is aimed at clarifying this point. However, we have been able to demonstrate that oxidative stress is present in the brains of mice infected with cerebral malaria."

Oxidative stress is a situation in which there is an imbalance between the production of reactive oxygen-containing molecules that can damage cell structures and the body's ability to detoxify these molecules or repair the resulting damage.

Zimmerman and his colleagues found increased production of molecules indicative of high oxidative stress in the brains of mice with cerebral malaria. They also found that treating mice with a combination of chloroquine and two antioxidant agents, desferoxamine and N-acetylcysteine, at the first signs of cerebral malaria prevented both inflammatory and vascular changes in the tissues of the brain, as well as the development of persistent cognitive damage. The addition of antioxidants did not diminish the efficacy of chloroquine in eliminating Plasmodia
'/>"/>

Contact: Phil Sahm
phil.sahm@hsc.utah.edu
801-581-2517
University of Utah Health Sciences
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. New Mario Badescu Skin Care Product Combines Moisture, Sun Protection, and Antioxidants
2. COPPERTONE(R) Solar Research Center Unveils Studies on Efficacy of Topical Antioxidants in Sunscreens at 2010 Annual Meeting of The American Academy of Dermatology
3. Ingredient in red wine may prevent some blinding diseases
4. Silencing hepatitis B virus prevent recurrence of liver cancer
5. Kids Into Safe Skin (K.I.S.S) Officially Launches Today with a Mission to Create Awareness About Skin Cancer Detection and Prevention
6. Prevent Knee Pain with Knee Braces for Tennis
7. Sickle cell patients should be better monitored for constipation prevention
8. The Rubit Dog Tag Clips Making Big Pet Store Sales, Everyday Dog Ownership Easier, Preventing Broken Fingernails.
9. Brown Rice Bests White for Diabetes Prevention
10. Cost concerns prevent many cancer survivors from getting medical care
11. New function discovered in cancer-prevention protein
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... ... 31, 2015 , ... Ticket Down is a reliable source of authentic ... new and refreshing show on Broadway, look no further than Hamilton. This American musical ... Outer Critics Circle Award, Drama Desk Award, Lucille Lortel Award, and New York Drama ...
(Date:7/31/2015)... CA (PRWEB) , ... July 31, 2015 , ... According ... and cosmetic experts gathered to see if they could reach a consensus on the ... breast augmentation and facelifts. Overall, the group reached 90 percent consensus on a series ...
(Date:7/31/2015)... York (PRWEB) , ... July ... ... attorney Jason T. Brown’s live lecture on pharmaceutical negligence is now available ... 2015 was well received with a 94% approval rating from the nationwide ...
(Date:7/31/2015)... ... July 31, 2015 , ... As part of their company mission, Dallas ... animal welfare organizations is essential to the longevity of their business. It is ... Association of Professional Pet Sitters (NAPPS) annual Presents 4 Pets supply drive. ...
(Date:7/31/2015)... ... , ... Transfinder, a software company based in Schenectady, N.Y., achieved record revenue ... for the first six months ended June 30, 2015 compared with the same period ... year’s record-revenue mark of $10.4 million. , “We know what our customers need and ...
Breaking Medicine News(10 mins):Health News:Cheap Hamilton Tickets at Richard Rodgers Theatre: Ticket Down Slashes Ticket Prices for Hamilton in New York City at the Richard Rodgers Theatre 2Health News:Cheap Hamilton Tickets at Richard Rodgers Theatre: Ticket Down Slashes Ticket Prices for Hamilton in New York City at the Richard Rodgers Theatre 3Health News:Cheap Hamilton Tickets at Richard Rodgers Theatre: Ticket Down Slashes Ticket Prices for Hamilton in New York City at the Richard Rodgers Theatre 4Health News:Cheap Hamilton Tickets at Richard Rodgers Theatre: Ticket Down Slashes Ticket Prices for Hamilton in New York City at the Richard Rodgers Theatre 5Health News:Cheap Hamilton Tickets at Richard Rodgers Theatre: Ticket Down Slashes Ticket Prices for Hamilton in New York City at the Richard Rodgers Theatre 6Health News:Cheap Hamilton Tickets at Richard Rodgers Theatre: Ticket Down Slashes Ticket Prices for Hamilton in New York City at the Richard Rodgers Theatre 7Health News:Article on Plastic Surgery Consensus Highlights the Duties of Veteran Plastic Surgeons, says Beverly Hills Physicians 2Health News:Article on Plastic Surgery Consensus Highlights the Duties of Veteran Plastic Surgeons, says Beverly Hills Physicians 3Health News:Re-Broadcast of Nationally Renowned Trial Attorney Jason T. Brown's Lecture on Pharmaceutical Negligence Now Available 2Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 2Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 3Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 4Health News:Transfinder Closes First Half of 2015 with Record Revenue 2
... Nov. 6 A multi-disciplinary,assessment team will be ... Ill., Hospital to review recent allegations made by ... Department announced,today., The team will assess personnel ... to equal employment opportunity; assess how,well employees and ...
... of the Nissan Quest,and their families can breathe easy ... This is thanks to micronAir(R) combination filters - a,product ... be,featured on the Quest. The combination filters from ... through the HVAC system, reducing offensive odors as well ...
... by diesel fuel in vehicles is leading to a ... or stroke, researchers suggested in the report of a ... Sessions 2007., United Kingdom and Swedish researchers found that ... in healthy volunteers which could lead to heart ...
... 2007 Elsevier announced today that major ... Leverkusen, Germany, has signed an agreement to purchase ... the first time, EMBASE Classic is a fully ... Abstract Journals published between 1947 and 1973. ...
... might lessen memory loss, study suggests , , TUESDAY, Nov. ... in patients with high blood pressure or a type ... found. , "The main point of these findings is ... in Alzheimer,s, so treatment of these factors could reduce ...
... healthiest ... new functional water, PLANO, Texas, Nov. 6 As more ... Antioxidant Water and,LYTeWater takes drinking water to the next level. ... helps restore the body and supports a healthy immune,system for consumers ...
Cached Medicine News:Health News:VA Deploying Assessment Team to Marion Medical Center 2Health News:Quality Control: Nissan Quest to Feature micronAir(R) Combination Cabin Air Filters 2Health News:Diesel exhaust associated with higher heart attack, stroke risk in men 2Health News:Diesel exhaust associated with higher heart attack, stroke risk in men 3Health News:EMBASE Classic makes inroads into pharmaceutical industry 2Health News:Blood Pressure, Heartbeat Problems Aggravate Alzheimer's 2Health News:Blood Pressure, Heartbeat Problems Aggravate Alzheimer's 3Health News:Snapple's New Antioxidant Water and LYTeWater Take Hydration to the Next Level 2Health News:Snapple's New Antioxidant Water and LYTeWater Take Hydration to the Next Level 3
(Date:7/30/2015)... 2015 PTC Therapeutics, Inc. (NASDAQ: PTCT ... results for the second quarter ending June 30, 2015. ... across the organization.  We are excited to be near ... trial ever conducted with topline results expected in the ... Officer, PTC Therapeutics, Inc. "Translarna is now commercially available ...
(Date:7/30/2015)... 2015  Cleveland Clinic President Wael Barsoum , ... month that industry is compelled to adopt declining reimbursements ... efficiencies—and develop the transformational innovations -- required to thrive ... preceded by Doug Kohrs , past President and ... stressed that industry must add "episode of care," also ...
(Date:7/30/2015)... , July 30, 2015 Future ... report titled, "Continuous Glucose Monitoring Systems Market: Global Industry ... the report, the global continuous glucose monitoring systems market ... is expected to reach US$ 788.4 Mn by 2020, ... 2015 to 2020. Global continuous glucose monitoring ...
Breaking Medicine Technology:PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 2PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 3PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 4PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 5PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 6PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 7PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 8PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 9PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 10Orthopaedic Surgery Reimbursement Shifts to Episode of Care 2Global Continuous Glucose Monitoring (CGM) Systems Market: Transmitters and Monitors Most Dominant Segment, Says Future Market Insights 2Global Continuous Glucose Monitoring (CGM) Systems Market: Transmitters and Monitors Most Dominant Segment, Says Future Market Insights 3Global Continuous Glucose Monitoring (CGM) Systems Market: Transmitters and Monitors Most Dominant Segment, Says Future Market Insights 4
... presented at 2008 ICAAC/IDSA Joint Meeting, ... a,clinical-stage biopharmaceutical company focused on commercializing,products to ... the,successful demonstration of synergistic activities and improvement ... vitro combination,studies of Sequella lead TB drug ...
... PharmAthene, Inc.,(NYSE ALTERNEXT US: PIP), a biodefense ... today announced,that dosing of volunteers has begun in ... safety and tolerability in humans. Protexia(R),which is produced ... recombinant version,of human butyrylcholinesterase (BChE), which has been ...
Cached Medicine Technology:Sequella Presents Data on Synergy Between Investigational New TB Drugs SQ109 and TMC207 2PharmAthene Initiates Phase I Clinical Trial of Nerve Agent Bioscavenger Protexia(R) 2PharmAthene Initiates Phase I Clinical Trial of Nerve Agent Bioscavenger Protexia(R) 3PharmAthene Initiates Phase I Clinical Trial of Nerve Agent Bioscavenger Protexia(R) 4PharmAthene Initiates Phase I Clinical Trial of Nerve Agent Bioscavenger Protexia(R) 5
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Infusion Cannula, 4.0mm....
Medicine Products: