Navigation Links
Antioxidants do not prevent degenerative eye disease
Date:10/8/2007

A diet rich in antioxidant vitamins and minerals does not seem to prevent the degenerative eye disease known as age related macular degeneration, finds a study published on bmj.com today.

Age related macular degeneration is the leading cause of visual loss in older people. It is caused by the progressive break down of light sensitive cells in the macula, located in the centre of the retina at the back of the eye. Sufferers do not go blind, but find it virtually impossible to read, drive, or do tasks requiring fine, sharp, central vision.

Risk increases with age and smokers are thought to be more susceptible.

Antioxidants (such as vitamin C, vitamin E, various types of carotenoids, and zinc) are thought to reduce oxidative damage to the retina. But the evidence to support the role of dietary antioxidants in preventing macular degeneration remains unclear.

So researchers at the Centre for Eye Research Australia, the University of Melbourne analysed the evidence to examine the role of dietary antioxidants or dietary supplements in the primary prevention of age related macular degeneration.

They identified 11 studies (seven prospective studies and three randomised controlled trials) involving 149,203 people. A range of common dietary antioxidants were investigated and all the studies were carried out amongst well nourished Western populations with an average follow-up period of nine years.

Importantly, all the studies adjusted for age and smoking in their analyses.

The antioxidants investigated differed across studies, but when results were pooled they showed that vitamin A, vitamin C, vitamin E, zinc, lutein, zeaxanthin, α- carotene, β-carotene, β-cryptoxanthin and lycopene have little or no effect in the primary prevention of early age-related macular degeneration.

None of the three trials found antioxidant supplements to be protective in the primary prevention of early age related macular degeneration.

Despite some study limitations, the authors conclude that there is insufficient evidence to support the role of dietary antioxidants, including the use of dietary antioxidant supplements, for the primary prevention of early age-related macular degeneration.

Currently, cigarette smoking remains the only widely accepted modifiable risk factor for the primary prevention of early age-related macular degeneration, and patients seeking advice on this condition should be encouraged to quit, they add.

An accompanying editorial by Jennifer Evans at the International Centre for Eye Health supports these findings and says that reducing the prevalence of smoking is probably the most effective method of reducing the population burden of this common cause of visual loss in older people.


'/>"/>
Contact: Emma Dickinson
edickinson@bmj.com
44-020-738-36529
BMJ-British Medical Journal
Source:Eurekalert

Related medicine news :

1. Antioxidants protect health tissue in people undergoing radiation therapy.
2. Antioxidants found in chocolates
3. Antioxidants used for longevity
4. Herbs: rich soure of antioxidants
5. Herbs: rich soure of antioxidants
6. Antioxidants found in chocolates
7. Sweet corn releases antioxidants on cooking
8. The Use Of Antioxidants To Diminish Effects of Alcohol During Pregnancy Questioned
9. Commercial grape juices and vinegars found rich in antioxidants
10. Antioxidants in the body protects the airways from diesel exhaust effect
11. Fruit And Vegetable Peels Are Rich Source Of Potent Antioxidants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... While it’s often important ... problem. Fortunately, an inventor from Austin, Texas, has identified a solution. , She developed ... darkness or restricted lighting. As such, it eliminates the need to turn on a ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Pharmacy (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, ... guideline updates for the primary prevention of cardiovascular diseases during the 15th ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of ... collection of specialty vendors and unique items from across the nation, this holiday-themed event ... wellness services offered by the VNA. The boutique will be open Saturday, November ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor ... on sciatica in a new episode of "Success Files," which is an award-winning ... innovation and investigates each subject in-depth with passion and integrity. , Sciatica occurs ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare ... program management, will showcase a range of technology and learning solutions at the ... Convention and Expo to be held October 14–18, 2017 at the Mandalay Bay ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... R.I. , Sept. 25, 2017  EpiVax, ... assessment, vaccine design, and immune-engineering today announced the ... on the development of personalized therapeutic cancer vaccines. ... has provided exclusive access to enabling technologies to ... Eng., MBA will lead EpiVax Oncology as Chief ...
(Date:9/22/2017)... , Sept. 22, 2017 AVACEN Medical ... device is now successfully helping those with the widespread ... Fibromyalgia diagnosed Amanda in Essex, England ... and washing my hair, experiencing no sleep at all, ... painful spasm… I cannot recommend [the AVACEN 100] enough, ...
(Date:9/18/2017)... KALAMAZOO, Mich. , Sept. 18, 2017 /PRNewswire/ ... and OptiMed Specialty Pharmacy of Kalamazoo, Mich. ... a strategic hub service that expedites and streamlines patient ... spirometer, Spiro PD 2.0, and wellness management services.  ... a medical device used to measure lung function for ...
Breaking Medicine Technology: