Navigation Links
Antioxidant supplements may lessen benefit of radiation and chemotherapy
Date:5/27/2008

Cancer patients should avoid the routine use of antioxidant supplements during radiation and chemotherapy because the supplements may reduce the anticancer benefits of therapy, researchers concluded in a commentary published online May 27 in the Journal of the National Cancer Institute.

Radiation and many chemotherapy agents work to kill cells by inducing free radicals that damage DNA and proteins. Therefore, there is a possibility that taking antioxidant supplements, such as vitamin E or -carotene, may interfere with the therapies and reduce their anticancer activity. On the other hand, some investigators hypothesize that antioxidant supplementation may protect healthy tissues and reduce the side effects of treatment. Despite two decades of research into this question, no clear answer has appeared.

To evaluate the potential harms or benefits of antioxidant supplementation, Brian D. Lawenda, M.D., of the Naval Medical Center San Diego and colleagues reviewed all of the randomized trials they could identify that tested the effect of antioxidant supplements on radiation therapy or chemotherapy.

In the case of radiotherapy, they identified nine studies that addressed the question, including two meta-analyses. However, only three studies were randomized controlled trials designed to look at the clinical effect of antioxidant therapy on radiation. In the largest of the randomized trials, antioxidant supplementation was associated with a reduction in overall survival. One antioxidant agent, amifostine, which is already approved by the U.S. Food and Drug Administration to increase radioresistance in healthy salivary gland tissues, may protect normal tissues without increasing tumor radioresistance. Lawenda and colleagues caution that the question needs to be studied further before a solid conclusion can be made.

The authors identified 16 randomized controlled trials that examined the impact of antioxidant supplementation on
'/>"/>

Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
2. Antioxidant Supplements May Raise Womens Skin Cancer Risk
3. New research into plant colors sheds light on antioxidants
4. Antioxidants do not prevent degenerative eye disease
5. Major ORAC Differences Among Top Antioxidant Beverages
6. Grape Consumption Improves Antioxidant Capacity in Humans
7. Snapples New Antioxidant Water and LYTeWater Take Hydration to the Next Level
8. Citrus juice, vitamin C give staying power to green tea antioxidants
9. Natural Antioxidants Help Reduce Oxidative Stress in Diabetes Treatment
10. New Research Confirms Wild Blueberry Antioxidant Power
11. Citrus Juice Gives Boost to Green Tea Antioxidants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... 2014 Pulmonary Hypertension Association goes ... Forum for PH patients and families to help ... Hypertension Association – the country’s leading pulmonary ... prevent and cure pulmonary hypertension (PH) – a ... of the heart and can lead right to ...
(Date:8/21/2014)... 21, 2014 The City of Garden ... entertainment and programming for its inaugural “Re:Imagine Garden Grove ... 12, 2014, from 11 a.m. to 4 p.m., 2.85-miles ... cars and the downtown will be filled with diverse ... Community Arts Resources (CARS), for all to enjoy. , ...
(Date:8/21/2014)... Dennis Thompson HealthDay Reporter ... A combination of therapy and antidepressants appears to best ... study reports. Four out of five people suffering ... full recovery when treated with cognitive therapy plus antidepressant ... combination didn,t work much better than drugs alone in ...
(Date:8/21/2014)... To sexually objectify a woman is to focus on ... sexual pleasure rather than viewing her as a complete ... long been considered a problem in the media, how ... in Psychology of Women Quarterly , a SAGE ... body is related to higher incidents of sexual pressure ...
(Date:8/21/2014)... 2014 The world wound care market ... 2014 and reach USD 18.3 billion by 2019, posting ... drivers of such growth include governments’ contribution to the ... population, and surging ageing population. However, the growth could ... products. Region-wise, North America leads the global wound care ...
Breaking Medicine News(10 mins):Health News:Pulmonary Hypertension Association Goes On the Road to Houston With an Education Forum for PH Patients and Families to Help Fight Rare Lung Disease 2Health News:Pulmonary Hypertension Association Goes On the Road to Houston With an Education Forum for PH Patients and Families to Help Fight Rare Lung Disease 3Health News:"Re:Imagine Garden Grove - A Downtown Open Streets Event" 2Health News:"Re:Imagine Garden Grove - A Downtown Open Streets Event" 3Health News:"Re:Imagine Garden Grove - A Downtown Open Streets Event" 4Health News:Talk Therapy Plus Meds May Be Best for Severe Depression 2Health News:Talk Therapy Plus Meds May Be Best for Severe Depression 3Health News:Objectification in romantic relationships related to sexual pressure and coercion 2Health News:Global Wound Care Market to Post 3.2% CAGR Through 2019, Says MarketsandMarkets in Its New Report Published at MarketPublishers.com 2Health News:Global Wound Care Market to Post 3.2% CAGR Through 2019, Says MarketsandMarkets in Its New Report Published at MarketPublishers.com 3
... management and technology infrastructure to replace insurance companies. , ... ... healthcare in this country is in crisis, that it is unaffordable ... solutions range from adopting a universal healthcare plan to lowering malpractice ...
... Lawyers to Offer "Safe and Sober Free Cab Ride Home" , ... ... Lawyers will be adding Halloween to its list of holidays for the ... team up with Veterans Cab and Yellow Cab in Alameda and Luxor ...
... Decision Intelligence,s Matt Redlon. , ... ... Technology Officer and Cofounder of Decision Intelligence, recently participated in ... ( www.BeyeNETWORK.com ). In this interview, Redlon explains how Decision ...
... and photographer, Laura Young, launches a line of products inspired by ... aid of braces, will be the recipient of all proceeds. ... ... Schwass was a star high school athlete with dreams of playing ...
... that educational literature can influence young women,s use of indoor ... by changing their attitudes about indoor tanning and promoting healthier ... December 1, 2008 issue of CANCER , a peer-reviewed ... there are more than 1.3 million skin cancer diagnoses in ...
... Report Released Today, SOUTH BEND, Ind., Oct. ... released today confirms patients have heightened expectations,of their ... choose where,they receive care. Health care facilities must ... to maintain and improve patient retention,rates. The 2008 ...
Cached Medicine News:Health News:CEO Proposes a Radical Plan to Revamp the Healthcare System 2Health News:CEO Proposes a Radical Plan to Revamp the Healthcare System 3Health News:Free Cab Rides Home for Halloween in Alameda, Oakland, Berkeley and San Francisco, California 2Health News:Free Cab Rides Home for Halloween in Alameda, Oakland, Berkeley and San Francisco, California 3Health News:Decision Intelligence Delivers Marketing Contact Optimization Solutions 2Health News:Decision Intelligence Delivers Marketing Contact Optimization Solutions 3Health News:Quadriplegic Man Defied the Odds, Continues to Inspire 2Health News:Quadriplegic Man Defied the Odds, Continues to Inspire 3Health News:Educational materials can alter young women's attitudes about tanning, may reduce skin cancer 2Health News:Report Confirms Consumer Selection is a Driving Force in Health Care Today 2Health News:Report Confirms Consumer Selection is a Driving Force in Health Care Today 3
(Date:8/21/2014)... , Aug. 21, 2014  Seventy-one percent of Americans ... OxyContin is a serious public health and safety issue in ... from a survey released today by Repass & Partners, a ... "Americans understand the severity of the prescription medication ... progress with this very serious health situation facing our country," ...
(Date:8/21/2014)... 21, 2014 InfinityQS International, Inc., the ... Intelligence , today announces Infusion Chicago, its 9 ... be held Oct. 9-10, 2014, at the Chicago ... showcase the necessity for implementing a quality system ... Intelligence to gain insight into production processes. Complimentary ...
(Date:8/21/2014)... Professional Compounding Centers of America (PCCA) ... the three best scientific presentations at the sixth ... The Formulating Better Medicines for Children  conference, ... Athens, Greece , includes dozens of poster-style ... which three winners will be selected by a ...
Breaking Medicine Technology:Consumers Desperate For Measures To Curb Prescription Drug Abuse 2Consumers Desperate For Measures To Curb Prescription Drug Abuse 3InfinityQS to Host Manufacturing Intelligence Conference in Chicago 2Professional Compounding Centers of America will award top poster-session winners at European Paediatric Formulation Initiative in Athens 2
... April 21 Tomato products may protect against ... recent multi-center, randomized, controlled trial on the effects ... in overweight and obese men and women, presented ... Giordano, Ph.D. on April 19, 2009 at the ...
... Leads to Weight Loss, Lower Blood Sugar and Improved A1CHORSHAM, ... a leading weight loss program that delivers to your door, ... loss program designed specifically for the approximately 24 million Americans ... are at risk for diabetes. In a clinical study ...
Cached Medicine Technology:Processed Tomato Products May Protect Against Inflammation, According to a Study Presented at the Experimental Biology Meeting 2Processed Tomato Products May Protect Against Inflammation, According to a Study Presented at the Experimental Biology Meeting 3New Weight Loss Hope for People with Diabetes 2New Weight Loss Hope for People with Diabetes 3New Weight Loss Hope for People with Diabetes 4New Weight Loss Hope for People with Diabetes 5New Weight Loss Hope for People with Diabetes 6
... a world leader in precision optics ... its new Universal Epi-Fluorescence Reflected Light ... microscope models, including the E600, E600FN, ... Epi Illuminator provides superior fluorescence imaging ...
... incorporates a Progressive Scan 1/3" CCD with square ... 768 (V) XGA. Whats more the XCD-X710CR uses ... a "Bayer filter") and outputs the "raw color" ... be converted to a color image on the ...
... digital camera incorporates a Progressive Scan 1/3" ... sensitivity (1024 x 768 XGA pixel resolution). ... B/W images and features an easy-to-use asynchronous ... from 1/100,000 to 17.5 second, allowing for ...
... monochrome " 1.3 Megapixel FireWire camera suitable ... to simplify real-time uncompressed video display and ... video and digital still-image quality in an ... ideal for industrial inspection tasks involving brightfield ...
Medicine Products: