Navigation Links
Antioxidant supplements may lessen benefit of radiation and chemotherapy
Date:5/27/2008

Cancer patients should avoid the routine use of antioxidant supplements during radiation and chemotherapy because the supplements may reduce the anticancer benefits of therapy, researchers concluded in a commentary published online May 27 in the Journal of the National Cancer Institute.

Radiation and many chemotherapy agents work to kill cells by inducing free radicals that damage DNA and proteins. Therefore, there is a possibility that taking antioxidant supplements, such as vitamin E or -carotene, may interfere with the therapies and reduce their anticancer activity. On the other hand, some investigators hypothesize that antioxidant supplementation may protect healthy tissues and reduce the side effects of treatment. Despite two decades of research into this question, no clear answer has appeared.

To evaluate the potential harms or benefits of antioxidant supplementation, Brian D. Lawenda, M.D., of the Naval Medical Center San Diego and colleagues reviewed all of the randomized trials they could identify that tested the effect of antioxidant supplements on radiation therapy or chemotherapy.

In the case of radiotherapy, they identified nine studies that addressed the question, including two meta-analyses. However, only three studies were randomized controlled trials designed to look at the clinical effect of antioxidant therapy on radiation. In the largest of the randomized trials, antioxidant supplementation was associated with a reduction in overall survival. One antioxidant agent, amifostine, which is already approved by the U.S. Food and Drug Administration to increase radioresistance in healthy salivary gland tissues, may protect normal tissues without increasing tumor radioresistance. Lawenda and colleagues caution that the question needs to be studied further before a solid conclusion can be made.

The authors identified 16 randomized controlled trials that examined the impact of antioxidant supplementation on
'/>"/>

Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
2. Antioxidant Supplements May Raise Womens Skin Cancer Risk
3. New research into plant colors sheds light on antioxidants
4. Antioxidants do not prevent degenerative eye disease
5. Major ORAC Differences Among Top Antioxidant Beverages
6. Grape Consumption Improves Antioxidant Capacity in Humans
7. Snapples New Antioxidant Water and LYTeWater Take Hydration to the Next Level
8. Citrus juice, vitamin C give staying power to green tea antioxidants
9. Natural Antioxidants Help Reduce Oxidative Stress in Diabetes Treatment
10. New Research Confirms Wild Blueberry Antioxidant Power
11. Citrus Juice Gives Boost to Green Tea Antioxidants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... California (PRWEB) January 22, 2015 The City of ... at 10 a.m., to commemorate the 42nd anniversary of the Supreme ... States. , “It’s been 42 years since the Roe vs. Wade ... is still as present as ever,” said City of West Hollywood ...
(Date:1/22/2015)... 2015 The Incredible Bulk is a revolutionary ... increase lean muscle by up to 30lbs in less than ... of HealthyandFitZone.com’s Stan Stevenson, prompting an investigative review. , “Our ... step-by-step, scientific diet formula that allows the body to pack ...
(Date:1/22/2015)... January 22, 2015 Juvent Sports ( ... the 2015 PGA Merchandise Show to bestow a Juvent ... female amateur golfer, Arlene McKitrick. The award commemorated and ... golf tournament win. She won her first amateur tournament ...
(Date:1/22/2015)... Carinsurancesavings.biz has released a new blog post ... insurance . , Purchasing an accidental death and dismemberment ... This type of rider provides benefits if the insured dies ... a lesser form of life insurance. , AD&D is ...
(Date:1/22/2015)... IsoComforter, Inc. has introduced the most innovative and easy ... treat specific body parts and muscle groups. , IsoComforter, ... use patented cold therapy machine with the innovative IsoTube design ... injuries. IsoComforter has become the industry leader in cold ...
Breaking Medicine News(10 mins):Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2
... the American Civil Liberties Union are questioning the policy ... and customs agents to detain travelers //who look like ... is reportedly available with Reuters, also allows Customs and ... ,Health and Human Services Secretary ...
... from joining up. These are new standards that have been ... the life of others, a new regulation ... has been ... as saying. ,The People's Liberation Army is the world's ... decided to ban people who wear tattoos. "Recruits with any ...
... foods shown on television poses a real threat on ... go for it thereby leading to overweight and obesity.// ... already associated childhood overweight with television viewing, but the ... and TV viewing is due to children’s physical inactivity ...
... making some simple changes in the diet will go a ... children eat and drink// makes a lot of difference in ... urologist at Baylor All Saints Medical Center in Fort Worth, ... should avoid the three Cs --caffeine, carbonation, and citrus. While ...
... conduct a weeklong education campaign, starting from Monday, to encourage ... art exhibitions// and plays. ,'The Rajya Shiksha Kendra ... campaign with the intention to bring all in the five ... the state's school education department said. ,'For ...
... use a towel when they are on the stationary bike or ... ,Fungi cause itchy rashes or in the worst case, ... Institute for Fungal Illness in Berlin. ,According to him, ... rubbed off the skin of someone infected and lands on the ...
Cached Medicine News:Health News:Junk Food Ads: The Culprit Behind Childhood Obesity 2
(Date:1/23/2015)... MONMOUTH JUNCTION, N.J. , Jan. 23, 2015 ... immunotherapy company commercializing its CytoSorb® extracorporeal cytokine adsorber ... surgery patients, announced the receipt of $385,642, net ... approved participant of the Technology Business Tax Certificate ...
(Date:1/23/2015)... 23, 2015 Gem Pharmaceuticals announced today that the ... into the Company,s Phase 2 clinical trial.  This open-label ... lead compound, GPX-150 (an investigational medication), in approximately 30 ... Logo - http://photos.prnewswire.com/prnh/20150123/170966LOGO ...
(Date:1/23/2015)... Tianyin Pharmaceutical Inc. (NYSE Amex: TPI ... and sale of patented biopharmaceutical medicine, modernized traditional Chinese ... today announced the business and development progress at its ... Following the September 2014 JCM application (No. 51268) for ...
Breaking Medicine Technology:CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 3Gem Pharmaceuticals Announces Enrollment of Initial Patients in its Phase 2 Clinical Trial to Assess the Efficacy and Safety of GPX-150 in Sarcoma Patients 2TPI's JCM Updates on Import Registration for International Clients 2TPI's JCM Updates on Import Registration for International Clients 3TPI's JCM Updates on Import Registration for International Clients 4
... announces that a new market research report is available ... Management Industry http://www.reportlinker.com/p087375/Global-Pain-Management-Industry.html ... Pain Management in US$ Million by the following product ... Management Services. The report provides separate comprehensive analytics for ...
... HONG KONG, Feb. 23, 2011 /PRNewswire-Asia/ -- Global ... its contracts with AsiaWorld-Expo Management (AWE) to host ... AsiaWorld-Expo from 2011 through 2014, in addition to the ... gross value of approximately US$16.7 million. (Logo: ...
Cached Medicine Technology:Reportlinker Adds Global Pain Management Industry 2Global Sources extends its contract with AsiaWorld-Expo to host China Sourcing Fairs in Hong Kong through 2014 2Global Sources extends its contract with AsiaWorld-Expo to host China Sourcing Fairs in Hong Kong through 2014 3
... Surgical's Breakthrough in Battery Powered Orthopedic Systems., ... revolutionary new addition to the Hall® Surgical ... Battery System is the first and only ... the market. It is a full-function orthopedic ...
... the new large power ... new handpieces function as ... instruments, offering the ultimate ... versatility the industry has ...
... OBIs proprietary PolyGraft® material technology which ... that is both biologically friendly and ... of polylactide-co-glycolide, calcium sulfate and polyglycolide ... fabricated into products such as granules, ...
... Release System is a technological breakthrough in ... a minimally-invasive approach, provides significant patient benefits. ... of the wrist,creates an entry for the ... a standard video camera system, provides a ...
Medicine Products: