Navigation Links
Antioxidant improves donated liver survival rate to more than 90 percent
Date:2/25/2013

Researchers from Italy have found that the antioxidant, N-acetylcysteine (NAC), when injected prior to harvesting of the liver, significantly improves graft survival following transplantation. Results published in the February issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases (AASLD), suggest that the NAC effect on early graft function and survival is higher when suboptimal organs are used.

A 2010 World Health Organization (WHO) report estimates that 22,000 liver transplants were performed worldwide, with nearly 18,500 from deceased donors. According to the Organ Procurement and Transplantation Network (OPTN) close to 16,000 U.S. patients are currently on the waiting list for a liver. Nearly 18,500 deceased donor transplants were performed between January and October 2012 in the U.S. OPTN reports that roughly 7,000 livers were recovered from deceased donors during the same time period.

"Liver transplantation is the standard treatment for end-stage liver disease," explains lead author Dr. Francesco D'Amico from Padova University in Italy. "Antioxidants such as NAC could potentially reduce damage to deceased donor livers, improving graft function." Studies have shown that ischemia-reperfusion injury (IFI)damage to the liver tissue when blood supply returns to the liver after lack of oxygen (ischemia)often occurs during storage and preservation of donated livers, and impacts early graft function post-transplantation.

For the present study researchers assigned 140 organs to adult candidates with liver disease undergoing their first transplant. An NAC infusion of 30 mg/kg was administered to one hour prior to liver procurement and another infusion of 300 mg (150mg/kg liver weight) through the portal vein before cross-clamping. There were 69 transplant candidates who received an NAC infused organ and 71 patients who had a standard transplant without NAC.

Results indicat
'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Page: 1 2

Related medicine news :

1. InVite® Health Introduces New and Improved Antioxidant Product – Cocoa Tx™
2. High-Antioxidant Diet May Not Prevent Stroke, Dementia, Study Finds
3. Used coffee grounds are a rich source of healthful antioxidants
4. Xoçai™ Activ, A Delicious, Healthy, Active-lifestyle Antioxidant Beverage Has Been Released by Marketing Xocolate International Corporation (MXI Corp)
5. Marketing Xocolate International Corporation (MXI-Corp) Introduces Xe Healthy Energy Drink, A Rich And Delicious Antioxidant Beverage, Now Added to Xoçai™ Product Line
6. Benefit6 Whole Body Protection, a New Product by I Do Strive LLC, Provides Maximum Antioxidant Protection
7. Supplements of Red Wine Antioxidant Dont Help Obese Men
8. Could Chocolates Antioxidants Boost Brain Function?
9. Antioxidants Might Help Cut Pancreatic Cancer Risk, Study Suggests
10. Antioxidant shows promise as treatment for certain features of autism, Stanford study finds
11. 'LKLiveMapping' Improves Laboratory Operating Efficiency, Delivers a High First-Submission Approval of Claims, and Improves Collection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... January 23, 2015 The U.S. Pharmacopeial ... DICVP, Director of Clinical Pharmacy Services at North Carolina ... recipient of the 2015 Beal Award for Distinguished Volunteer ... has relied on the contributions of volunteer experts to ...
(Date:1/22/2015)... (PRWEB) January 23, 2015 LunaDress, with its ... the fashion industry. Now, the business is showing its latest ... women’s dresses. , According to the company’s CEO, all the ... now offered with big discounts, up to 80% off. All ...
(Date:1/22/2015)... Woodloch Pines, an all-inclusive family resort ... TripAdvisor as the number one best large hotel for families ... world for their annual Travelers’ Choice Awards. , TripAdvisor ... website is home to millions of unbiased and honest traveler ...
(Date:1/22/2015)... Padre Murphy's and Owner Tom Boyle in ... Player Health Alliance (PPHA). The PPHA's passion for others' ... including NFL greats, treated for obstructive sleep apnea (OSA) has ... the cause in the valley. The most recent plans for ...
(Date:1/22/2015)... The Incredible Bulk is a revolutionary method ... lean muscle by up to 30lbs in less than 12 ... HealthyandFitZone.com’s Stan Stevenson, prompting an investigative review. , “Our ... scientific diet formula that allows the body to pack on ...
Breaking Medicine News(10 mins):Health News:Gigi Davidson, Pioneer in Veterinary Pharmacy and Leader in Pharmacy Compounding, honored with USP’s Beal Award for Dedication to Public Health 2Health News:Gigi Davidson, Pioneer in Veterinary Pharmacy and Leader in Pharmacy Compounding, honored with USP’s Beal Award for Dedication to Public Health 3Health News:Gigi Davidson, Pioneer in Veterinary Pharmacy and Leader in Pharmacy Compounding, honored with USP’s Beal Award for Dedication to Public Health 4Health News:LunaDress Shows The Latest Styles Of Wedding Dresses In 2015 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 3Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2
... adults on Medicare reports drinking more alcohol than is ... , Even though alcohol problems are more prevalent ... are consuming alcohol in amounts that exceed recommended guidelines, ... Universitys Heller School for Social Policy and Management. The ...
... Year Revenue Up 47.3% and Net Income Up 63.5% ... Company Declares Cash Dividend of US$0.18 ... Mindray,Medical International Limited (NYSE: MR ), a leading ... a rapidly growing,international presence, today announced its selected unaudited ...
... infertility risks, experts say , , WEDNESDAY, March 5 ... targeted treatment than standard chemotherapy, the effective and much-touted ... women still in their reproductive years, imatinib (Gleevec) might ... future, according to a case report published as a ...
... WALNUT CREEK, Calif., March 5 Longs Drug,Stores ... income from,continuing operations for the fourth quarter ended ... or $1.00 per diluted share, including a,$1.1 million ... of seven,California stores. Income from continuing operations for ...
... MED ) announced today that it will release fourth quarter ... 2007 on,Wednesday, March 12, 2008 after the market closes. The ... results on Thursday, March 13,2008 at 11:00 a.m. ET., ... or,(201) 689-8567, or can listen via a live Internet web ...
... 2008 The American Cancer Society, the American College ... on Colorectal Cancer (a group that comprises representatives ... Association, and American Society for Gastrointestinal Endoscopy) have ... cancer screening. The guidelines add two new tests ...
Cached Medicine News:Health News:New study sheds light on excessive drinking among the elderly 2Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 2Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 3Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 4Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 5Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 6Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 7Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 8Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 9Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 10Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 11Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 12Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 13Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 14Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 15Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 16Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 17Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 18Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 19Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 20Health News:Mindray Medical International Announces Full Year and Fourth Quarter 2007 Results 21Health News:Gleevec May Disrupt Ovarian Function 2Health News:Gleevec May Disrupt Ovarian Function 3Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 2Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 3Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 4Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 5Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 6Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 7Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 8Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 9Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 10Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 11Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 12Health News:Longs Drug Stores Corporation Reports Results for Fourth Quarter and Fiscal Year 2008 13
(Date:1/23/2015)... and Markets ( http://www.researchandmarkets.com/research/vzhr6h/video ) has announced the ... Size, Share, Growth, Trends and Forecast 2014 - 2020" ... the topic of fascination since the era of the cold ... the Soviet Russia. Earlier even a small glimpse of human ...
(Date:1/23/2015)... Biotherapeutics, Inc. (NASDAQ: NWBO )("NW Bio"), a U.S. ... inoperable solid tumor cancers, announced today that CEO Linda ... Phacilitate Immunotherapy Forum in Washington D.C. ... on January 26 at 10:30 a.m. EST at the Grand ...
(Date:1/23/2015)... 2015  Pete Rose, baseball,s all-time hits leader, is the new ... Myoflex, Ducere Pharma has announced. "Pete,s a Hall ... have him on board with Myoflex," said Ducere Pharma Chief ... player who is known across all generations. The passion and ...
Breaking Medicine Technology:Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3Pete Rose bets on Myoflex to relieve aches and pains 2
... 7, 2011 Henry Schein, Inc., (Nasdaq: ... and services to office-based practitioners, announced today that ... Schein, and Steven Paladino, the Company,s Executive Vice President and ... Global Healthcare Services Conference on February 8, 2011. The conference ...
... Inovio Pharmaceuticals, Inc. (NYSE Amex: INO ... preventive vaccines against cancers and infectious diseases, announced today ... provides the powerful enabling capabilities of electroporation without contacting ... the scientific journal Human Vaccines . While current ...
Cached Medicine Technology:Henry Schein to Present at the UBS 21st Annual Global Healthcare Services Conference 2Inovio Pharmaceuticals Unveils Needle-free, Contactless Electroporation Technology for DNA Vaccine Delivery 2Inovio Pharmaceuticals Unveils Needle-free, Contactless Electroporation Technology for DNA Vaccine Delivery 3Inovio Pharmaceuticals Unveils Needle-free, Contactless Electroporation Technology for DNA Vaccine Delivery 4Inovio Pharmaceuticals Unveils Needle-free, Contactless Electroporation Technology for DNA Vaccine Delivery 5
The anti-MAG autoantibodies EIA employs the quantitative enzymatically amplified sandwich-type immunoassay technique. HIGHLY PURIFIED MAG FROM HUMAN BRAIN has been precoated onto a microtiter plate....
... new Enzyme Immuno Assay (EIA) analyzer offering ... a dedicated EVO platform for reliable EIA ... and incubation units operated by the new ... available in three sizes - 100, 150, ...
... trial for 14 years -- and works! ... employs cutting-edge, patent-pending technology to attain the ... unsurpassed accuracy. The technique traces the amount ... blood to determine gender. Here's how it ...
Custom Pediatric Nebulizer Assembly W/Tubing...
Medicine Products: