Navigation Links
Antioxidant drug knocks down multiple sclerosis-like disease in mice
Date:12/26/2013

PORTLAND, Ore. Researchers at Oregon Health & Science University have discovered that an antioxidant designed more than a dozen years ago to fight damage within human cells significantly helps symptoms in mice that have a multiple sclerosis-like disease.

The antioxidant called MitoQ has shown some promise in fighting neurodegenerative diseases. But this is the first time it has been shown to significantly reverse an MS-like disease in an animal.

The discovery could lead to an entirely new way to treat multiple sclerosis, which affects more than 2.3 million people worldwide.

Multiple sclerosis occurs when the body's immune system attacks the myelin, or the protective sheath, surrounding nerve fibers of the central nervous system. Some underlying nerve fibers are destroyed. Resulting symptoms can include blurred vision and blindness, loss of balance, slurred speech, tremors, numbness and problems with memory and concentration.

The antioxidant research was published in the December edition of Biochimica et Biophysica Acta Molecular Basis of Disease. The research team was led by P. Hemachandra Reddy, Ph.D., an associate scientist in the Division of Neuroscience at OHSU's Oregon National Primate Research Center.

To conduct their study, the researchers induced mice to contract a disease called experimental autoimmune encephalomyelitis, or EAE, which is very similar to MS in humans. They separated mice into four groups: a group with EAE only; a group that was given the EAE, then treated with the MitoQ; a third group that was given the MitoQ first, then given the EAE; and a fourth "control" group of mice without EAE and without any other treatment.

After 14 days, the EAE mice that had been treated with the MitoQ exhibited reduced inflammatory markers and increased neuronal activity in the spinal cord an affected brain region in MS that showed their EAE symptoms were being improved by the treatment. The
'/>"/>

Contact: Todd Murphy
murphyt@ohsu.edu
503-494-8231
Oregon Health & Science University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Antioxidant shows promise as treatment for certain features of autism, Stanford study finds
2. Antioxidants Might Help Cut Pancreatic Cancer Risk, Study Suggests
3. Could Chocolates Antioxidants Boost Brain Function?
4. Supplements of Red Wine Antioxidant Dont Help Obese Men
5. Benefit6 Whole Body Protection, a New Product by I Do Strive LLC, Provides Maximum Antioxidant Protection
6. Marketing Xocolate International Corporation (MXI-Corp) Introduces Xe Healthy Energy Drink, A Rich And Delicious Antioxidant Beverage, Now Added to Xoçai™ Product Line
7. Xoçai™ Activ, A Delicious, Healthy, Active-lifestyle Antioxidant Beverage Has Been Released by Marketing Xocolate International Corporation (MXI Corp)
8. Used coffee grounds are a rich source of healthful antioxidants
9. High-Antioxidant Diet May Not Prevent Stroke, Dementia, Study Finds
10. InVite® Health Introduces New and Improved Antioxidant Product – Cocoa Tx™
11. Antioxidant improves donated liver survival rate to more than 90 percent
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antioxidant drug knocks down multiple sclerosis-like disease in mice
(Date:5/23/2015)... May 23, 2015 On May 13, ... of a youngster's yogic power learned through meditation and ... Swami in Bangalore, India. , Yogamaatha, a nine-year-old girl ... 50 high profile professionals attending the 2015 Business Advocacy ... fluently -- blindfolded. , In a demonstration that ...
(Date:5/23/2015)... On Wednesday, May 20, 2015, CareFirst ... been the target of a sophisticated cyberattack,” and that ... ongoing Information Technology (IT) security efforts in the wake ... most notable attack on health insurers was reported in ... second largest health insurer, revealed that they had suffered ...
(Date:5/23/2015)... A live auction will be held to ... centers and other medical facilities around the United States. ... radiology, surgery, anesthesia, exam and much more. , The ... May 28 starting at 9:00am CDT each day. The equipment ... Avenue, Melrose Park, IL 60160. Anyone can participate in ...
(Date:5/23/2015)... Injury lawyer Steven H. Heisler commented today on the ... legislature but which has not been signed to date by ... 449 with overwhelming bipartisan support on April 10, 2015, ... This bill ensures that fracking is prohibited in Maryland through ... of fracking to our water supplies and the air we ...
(Date:5/22/2015)... The American College of Traditional Chinese ... They will hold a webinar on the updates of ... on Classical Chinese Medicine. , Webinar – First Professional ... the Dean of Clinical Education, will lead this webinar ... Doctorate program. ACTCM is currently developing this degree program ...
Breaking Medicine News(10 mins):Health News:Nine-Year-Old Reads Blindfolded at Business Advocacy Summit 2Health News:Nine-Year-Old Reads Blindfolded at Business Advocacy Summit 3Health News:One Headline Making Cyber Attack Sparks Discovery of Another 2Health News:One Headline Making Cyber Attack Sparks Discovery of Another 3Health News:One Headline Making Cyber Attack Sparks Discovery of Another 4Health News:Over 5,200 Lots of Medical Equipment Will Be Sold by Live Auction 2Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 2Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 3Health News:ACTCM Announces Upcoming June Events 2
... on the Rise New Tools to Help Make More ,Cents, ... Suze Orman,is the latest celebrity to join the famed Milk ... With rising food costs, many,families are economizing on groceries but ... about 25 cents per 8 ounce glass, on a gallon,basis, ...
... Women Do Not Feel Knowledgeable About Their,Cancer Risks and ... Educate and Entertain, LOS ANGELES, Sept. 29 ... Johnson and Nastia Liukin, along with Team USA,will join ... a national network,television special, Frosted Pink with a Twist, ...
... no concrete answers , , MONDAY, Sept. 29 (HealthDay News) -- ... likely to die after surgery than those who live in ... analyzed death rates among more than one million older adults ... surgeries between 1999 and 2003. , The risk of ...
... to support CMS, hospital-acquired,conditions payment reform efforts, ... National Business,Coalition on Health (NBCH) announced its ... Medicaid Services, (CMS) efforts to influence payment,reform ... Events" -- serious and,costly preventable hospital errors. ...
... In some cases, unproven ,therapies, can be dangerous, experts ... patients often turn to the Internet as a source ... those hopes are betrayed by purveyors of so-called cancer ... this month, five companies were charged with making false ...
... mesothelioma blog readers of improper removal of asbestos in St. Louis ... mesothelioma cancer. The city used an unapproved "wet method" of removing ... the water evaporates. , ... Denver, CO (PRWEB) September ...
Cached Medicine News:Health News:Suze Orman Joins got milk? Milk Mustache Campaign: New Ad Encourages Families To Invest in Milk's Nutritional Assets 2Health News:Suze Orman Joins got milk? Milk Mustache Campaign: New Ad Encourages Families To Invest in Milk's Nutritional Assets 3Health News:Video: 2008 US Olympic Gymnastic Superstars Join Today's Top Music Icons for Women's Cancer Awareness Network Special, Frosted Pink with a Twist 2Health News:Video: 2008 US Olympic Gymnastic Superstars Join Today's Top Music Icons for Women's Cancer Awareness Network Special, Frosted Pink with a Twist 3Health News:Video: 2008 US Olympic Gymnastic Superstars Join Today's Top Music Icons for Women's Cancer Awareness Network Special, Frosted Pink with a Twist 4Health News:Seniors in Poor Areas More Likely to Die After Surgery 2Health News:National Business Coalition on Health Endorses New CMS 'Never Events' Policy 2Health News:National Business Coalition on Health Endorses New CMS 'Never Events' Policy 3Health News:National Business Coalition on Health Endorses New CMS 'Never Events' Policy 4Health News:Scams and Shams That Prey on Cancer Patients 2Health News:Scams and Shams That Prey on Cancer Patients 3Health News:LegalView Reports Cancer Risk for St. Louis Residents After Unapproved Asbestos Removal During Demolition 2Health News:LegalView Reports Cancer Risk for St. Louis Residents After Unapproved Asbestos Removal During Demolition 3
(Date:5/22/2015)... 22, 2015  In a sweeping analysis assessing the ... T1D Exchange researchers conclude that there remains considerable ... across all age groups, but especially for adolescents and ... of diabetes treatment, underscoring the need to address barriers ... can help type 1 patients achieve optimal metabolic control. ...
(Date:5/22/2015)... , May 22, 2015  China Nepstar Chain ... a leading retail drugstore chain in China ... stores, today announced the resignation of Mr. Fuxiang ... personal reasons, effective immediately. Ms. Rebecca Yingnan Zhang ... the Company,s board of directors, effective immediately. Meanwhile, Ms. ...
(Date:5/21/2015)... 2015 Research and Markets ... the "North American Active Wound Care Market ... Wound, & Ulcer), by End-User (In-Patient, & Out-Paient) ... to their offering. ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ,The ... to grow at a CAGR of 3.1% from ...
Breaking Medicine Technology:Study Reveals Poor Disease Control Among Adolescents and Young Adults with Type 1 Diabetes 2Study Reveals Poor Disease Control Among Adolescents and Young Adults with Type 1 Diabetes 3Study Reveals Poor Disease Control Among Adolescents and Young Adults with Type 1 Diabetes 4Study Reveals Poor Disease Control Among Adolescents and Young Adults with Type 1 Diabetes 5China Nepstar Chain Drugstore Ltd. Announces Management Change and New Director Appointment 2China Nepstar Chain Drugstore Ltd. Announces Management Change and New Director Appointment 3North American Active Wound Care Market 2015-2019 with Smith and Nephew, Molyncke HealthCare & ConvaTec Dominating 2
... May 5 OrthoAccel Technologies, Inc. announced that it has entered ... to introduce the AcceleDent System to the Australian market. , ... (Logo: http://www.newscom.com/cgi-bin/prnh/20091029/DA01250LOGO ) , ... AcceleDent, an acceleration device to enhance orthodontics, was introduced ...
... Instrumentation Laboratory (IL) today announced total worldwide sales in 2009 ... growth v. previous year in current, and 13.2% in local currencies.  In ... growth in local currencies was 13.2% and 12.4%, respectively. , ... "In spite of the major economic downturn, ...
Cached Medicine Technology:OrthoAccel Technologies, Inc. and AB Orthodontics Announce Partnership and Australian Product Introduction 2OrthoAccel Technologies, Inc. and AB Orthodontics Announce Partnership and Australian Product Introduction 3OrthoAccel Technologies, Inc. and AB Orthodontics Announce Partnership and Australian Product Introduction 4Instrumentation Laboratory Achieves Record Sales in 2009 2Instrumentation Laboratory Achieves Record Sales in 2009 3
ENA Screen EIA Auto-Immune Markers 012-MDKES1 Extractable Nuclear Antigens...
Anti-MPO ANCA EIA Auto-Immune Markers 013-MPO-96 Myeloperoxidase...
... from patient serum or plasma, standards and controls ... wells. After a washing step, an alkaline ... the Fc region of human IgG. After ... followed by a stopping step. The absorption ...
...
Medicine Products: