Navigation Links
Antihistamine Meds May Raise Risk for Diarrheal Illness

FRIDAY, March 29 (HealthDay News) -- Patients who take antihistamines to reduce stomach acid are at increased risk for infection with Clostridium difficile, a common cause of diarrhea, a new study finds.

Researchers reviewed the findings of 33 previous studies that looked at C. difficile and antihistamines used to suppress stomach acid. People who took over-the-counter antihistamine drugs did not have a significantly increased risk of C. difficile infection.

However, a clear link existed between histamine 2 receptor antagonists -- a specific class of antihistamines -- and C. difficile infection. The risk for people on these drugs -- also known as H2 blockers -- was greatest for hospitalized patients receiving antibiotics, said the researchers from the Mayo Clinic in Rochester, Minn.

The study was published online March 27 in the journal PLoS One.

"It's not clear why these antihistamines increase the risk of C. difficile infection, because gastric acid does not affect C. difficile spores," senior author Dr. Larry Baddour, an infectious diseases expert, said in a Mayo Clinic news release. "However, it may be that vegetative forms of C. difficile, which are normally killed by stomach acid, survive due to use of stomach acid suppressors and cause infection."

The researchers said their findings highlight the need for careful use of histamine 2 receptor antagonists in hospitalized patients, and suggest that reducing the use of these drugs could significantly lower the risk of C. difficile infections.

Although the study tied use of these drugs to higher risk of diarrheal illness, it did not establish a cause-and-effect relationship.

More information

The American Academy of Family Physicians has more about Clostridium difficile infections.

-- Robert Preidt

SOURCE: Mayo Clinic, news release, March 27, 2013

Copyright©2012 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Side Plank Leg Raises Video Revealed by Bodyweight Torch
2. Isolation, Loneliness May Raise Death Risk for Elderly
3. Stress During Pregnancy May Raise Heart Defect Risk for Baby
4. Michigan Lupus Foundation Texas Hold 'Em Tournament Raises Thousands for Lupus Support, Education & Research
5. Having Older Grandfather May Raise Childs Autism Risk: Study
6. Stroke Before Age 50 Linked to Raised Risk of Early Death
7. Chuback Medical Group Raises Awareness for the Serious Vein Condition Deep Vein Thrombosis
8. New Guidelines Raise Safety Bar on Concussions
9. Night Shift Linked to Raised Risk of Ovarian Cancer
10. Major Bleeds After Heart Procedures May Raise Death Risk: Study
11. Mental Illness May Raise Risk of Being Murdered
Post Your Comments:
(Date:11/27/2015)... County, CA (PRWEB) , ... November 27, 2015 , ... ... season , The company is offering customers 10% off of their purchase of lice ... any treatment at full price. According to a company spokesperson. “Finding lice is a ...
(Date:11/27/2015)... , ... November 27, 2015 , ... ... the well-respected Microsoft Dynamics SL User Group (MSDSLUG). Recognized as Microsoft’s official group ... group of Microsoft Dynamics SL software users, partners, industry experts and representatives. Intellitec ...
(Date:11/27/2015)... ... November 27, 2015 , ... The men and women ... healthcare organizations in the country. They have overseen financial turnarounds, shown commitment to ... the healthcare industry as a whole through their advocacy and professional efforts. , ...
(Date:11/26/2015)... ... November 26, 2015 , ... Inevitably when people think Thanksgiving, they ... to buy during the Black Friday and Cyber Monday massage chair sales ... the Internet high and low to find the best massage chair deals, they can ...
(Date:11/26/2015)... TX (PRWEB) , ... November 26, 2015 , ... PRMA ... On November 19, 2015, our surgeons performed their 6,000th free flap breast reconstruction surgery! ... “We wake up every day excited to rebuild lives and it’s an honor to ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 2015 ) ... "Radioimmunoassay Market by Type (Reagents & Kits, ... Clinical Diagnostic Labs), Application (Research, Clinical Diagnostics), ... report to their offering. --> ... of the "Radioimmunoassay Market by Type ...
(Date:11/25/2015)... -- The total global healthcare industry is expected to grow at ... America has the highest projected growth at 12.7%, ... ), is second with growth projected at 11.5%. ... expenditure. In 2013-2014, total government funded healthcare was nearly 68%. ... 41.2% in 2013-2014. In real terms, out of pocket expenditure ...
(Date:11/25/2015)... -- Linden Care, LLC, a retail specialty pharmacy focused on ... from chronic pain, said today that it is disappointed ... enjoining Express Scripts from unilaterally terminating the Pharmacy Provider ... --> The company said that it ... --> --> In the ...
Breaking Medicine Technology: