Navigation Links
Antihistamine Meds May Raise Risk for Diarrheal Illness
Date:3/29/2013

FRIDAY, March 29 (HealthDay News) -- Patients who take antihistamines to reduce stomach acid are at increased risk for infection with Clostridium difficile, a common cause of diarrhea, a new study finds.

Researchers reviewed the findings of 33 previous studies that looked at C. difficile and antihistamines used to suppress stomach acid. People who took over-the-counter antihistamine drugs did not have a significantly increased risk of C. difficile infection.

However, a clear link existed between histamine 2 receptor antagonists -- a specific class of antihistamines -- and C. difficile infection. The risk for people on these drugs -- also known as H2 blockers -- was greatest for hospitalized patients receiving antibiotics, said the researchers from the Mayo Clinic in Rochester, Minn.

The study was published online March 27 in the journal PLoS One.

"It's not clear why these antihistamines increase the risk of C. difficile infection, because gastric acid does not affect C. difficile spores," senior author Dr. Larry Baddour, an infectious diseases expert, said in a Mayo Clinic news release. "However, it may be that vegetative forms of C. difficile, which are normally killed by stomach acid, survive due to use of stomach acid suppressors and cause infection."

The researchers said their findings highlight the need for careful use of histamine 2 receptor antagonists in hospitalized patients, and suggest that reducing the use of these drugs could significantly lower the risk of C. difficile infections.

Although the study tied use of these drugs to higher risk of diarrheal illness, it did not establish a cause-and-effect relationship.

More information

The American Academy of Family Physicians has more about Clostridium difficile infections.

-- Robert Preidt

SOURCE: Mayo Clinic, news release, March 27, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Side Plank Leg Raises Video Revealed by Bodyweight Torch
2. Isolation, Loneliness May Raise Death Risk for Elderly
3. Stress During Pregnancy May Raise Heart Defect Risk for Baby
4. Michigan Lupus Foundation Texas Hold 'Em Tournament Raises Thousands for Lupus Support, Education & Research
5. Having Older Grandfather May Raise Childs Autism Risk: Study
6. Stroke Before Age 50 Linked to Raised Risk of Early Death
7. Chuback Medical Group Raises Awareness for the Serious Vein Condition Deep Vein Thrombosis
8. New Guidelines Raise Safety Bar on Concussions
9. Night Shift Linked to Raised Risk of Ovarian Cancer
10. Major Bleeds After Heart Procedures May Raise Death Risk: Study
11. Mental Illness May Raise Risk of Being Murdered
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in agile ... a contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise ... use of Agile methodologies in a consistent and high value manner across CMS ...
(Date:10/12/2017)... San Francisco, CA (PRWEB) , ... October 12, ... ... and Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus ... sleep apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) will ... during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual ... F. Collen, a pioneer in the field of medical informatics, this prestigious award is ...
(Date:10/12/2017)... PA (PRWEB) , ... October 12, 2017 , ... ... is the recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B ... York City on October 11, 2017. , The annual award competition recognizes editorial and ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... the nation's first interactive health literacy software tool, and the Cancer Patient Education ... of cancer patient education, today announce a new strategic alliance. , As ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... , Oct. 2, 2017  Eli Lilly and Company ... results for the third quarter of 2017 on Tuesday, ... call on that day with the investment community and ... The conference call will begin at 9 a.m. ... access a live webcast of the conference call through ...
(Date:9/28/2017)... , Sept. 28, 2017 Cohen Veterans Bioscience ... the use of wearable and home sensors for real-time ... Early Signal Foundation, a nonprofit organization focused on disruptive ... provide an affordable analytical system to record and integrate ... ...
(Date:9/23/2017)... 22, 2017 Janssen Biotech, Inc. (Janssen) announced ... from the U.S. Food and Drug Administration (FDA) for ... for the treatment of moderately to severely active rheumatoid ... data are needed to further evaluate the safety of ... RA. "We ...
Breaking Medicine Technology: