Navigation Links
Antidepressants May Hasten Bypass Recovery, Study Finds
Date:5/1/2013

WEDNESDAY, May 1 (HealthDay News) -- Depression is relatively common in patients who undergo heart bypass surgery, and a new study finds that short-term use of antidepressants may aid patients' recovery.

"Depression among patients requiring or having undergone [bypass] surgery is high and can significantly impact postoperative recovery," said one expert not connected to the study, Dr. Bryan Bruno, acting chairman of the department of psychiatry at Lenox Hill Hospital in New York City.

In this study, a team of French researchers looked at 182 patients who started taking a selective serotonin reuptake inhibitor (SSRI) antidepressant two to three weeks before undergoing coronary artery bypass graft surgery and continued taking it for six months after the procedure.

SSRIs include widely used antidepressants such as Celexa, Lexapro, Prozac, Paxil and Zoloft. In this study, patients took one 10 milligram tablet of Lexapro (escitalopram) daily. The study was funded by Lexapro's maker, H Lundbeck A/S.

The outcomes of patients prescribed Lexapro were compared to 179 patients who took an inactive placebo instead of the antidepressant.

During the six months after the surgery, the patients who took the antidepressant reported less depression and better quality of life than those who took the placebo, the researchers reported.

In addition, taking antidepressants did not increase the risk of complications or death in the year after surgery, according to the study, which appears in the May issue of the Annals of Thoracic Surgery.

The study suggests that taking the antidepressant "enables patients who were at least slightly depressed before surgery for coronary artery disease to feel better more quickly after surgery, without influencing the complication rate," study leader Dr. Sidney Chocron said in a journal news release.

"Even slight depression before coronary surgery can delay a patient's mental recovery and increase the feeling of pain after surgery," added Chocron, a professor of cardiac surgery at University Hospital Jean Minjoz in Besancon.

Prescribing antidepressants for patients before they have heart bypass surgery helps them "get on with their lives more quickly after such a serious surgical procedure," Chocron said in the news release.

Bruno agreed that treating even mild depression is important.

"I agree with the authors' concluding suggestion that, unless contraindicated, there should be a relatively low threshold . . . for initiating antidepressant therapy" in these types of heart patients, he said.

But another expert said the study reveals little about the strategy for patients with more severe depression.

"The mild benefit associated with the use of antidepressants in this study is consistent with a population which was not significantly depressed," noted Dr. Dan Iosifescu, director of the Mood and Anxiety Disorders Program and associate professor of psychiatry and neuroscience at Mount Sinai School of Medicine in New York City.

He said "the patients in this study had depressive symptoms in a range which usually does not qualify for a diagnosis of depression." Therefore, "on balance this study provides helpful information on the safety of antidepressants in post-[bypass] patients," Iosifescu said, "but does not contribute to our understanding of their usefulness since the study population appears to have very low rates of depression."

More information

The U.S. National Heart, Lung, and Blood Institute has more about coronary artery bypass graft surgery.

-- Robert Preidt

SOURCES: Bryan Bruno, M.D., acting chairman, department of psychiatry, Lenox Hill Hospital, New York City; Dan V. Iosifescu, M.D., director, Mood and Anxiety Disorders Program, and associate professor, psychiatry and neuroscience, Mount Sinai School of Medicine, New York City; Annals of Thoracic Surgery, news release, May 1, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Some Antidepressants Linked to Bleeding Risk With Surgery
2. Antidepressants for pregnant moms dont affect infants growth
3. Antidepressants Celexa, Lexapro Tied to Irregular Heartbeat: Study
4. Prenatal Antidepressants Dont Raise Fetal, Infant Death Risk: Study
5. When Antidepressants Dont Work, Give Counseling a Try
6. Common Antidepressants Tied to Higher Bleeding Risk in Warfarin Users: Study
7. Common Antidepressants Too Risky During Pregnancy, Researchers Say
8. Medicare Coverage Gap May Cause Seniors to Forgo Antidepressants
9. Publication Bias Casts Doubt on Value of Antidepressants for Autism
10. Newer Antidepressants May Be Safe for Parkinsons Patients
11. Minorities, Medicare Recipients Less Likely to Get Antidepressants
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antidepressants May Hasten Bypass Recovery, Study Finds
(Date:4/28/2017)... ... ... Pastor and Overseer at The House of Yahweh in Abilene, Texas, has published a new ... not. Yisrayl says with so many titles and names for the Creator, it’s hard ... a little Scripture, backed with a lot of research, the truth is undeniable. , ...
(Date:4/28/2017)... ... April 28, 2017 , ... Woolsy Corporation Limited, a ... its Nova Skin Sciences division, recently announced the launch of Allumière Antiaging Cream, ... power of an anti-aging concentrate. , Anogeissus Leiocarpa Bark Extract and ...
(Date:4/28/2017)... Tenn. (PRWEB) , ... April 28, 2017 , ... ... system, today announced an alliance with B. Braun Medical Inc. , a leader ... role in patient care with as many as 90 percent of hospital patients receiving ...
(Date:4/27/2017)... , ... April 27, 2017 , ... ... natural deodorant. On the heels of Thinksport’s award-winning sunscreen they’ve used the same ... that actually works! , Countless deodorants flood the aisles that contain harmful chemicals ...
(Date:4/27/2017)... ... April 27, 2017 , ... Goodcents Deli Fresh Subs announced ... Lincoln, Neb. area this year. , The first new location will open at ... will open at 84th and Northern Lights Drive this fall. And the third location ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... NEW YORK , April 19, 2017 /PRNewswire/ ... This report on the prostate cancer ... of the global market. Increasing prevalence of prostate ... as innovation in the development of new drugs ... hormone-refractory prostate cancer drug due to lesser side ...
(Date:4/19/2017)... April 19, 2017  Sorrento Therapeutics, Inc. (NASDAQ: ... biopharmaceutical company developing new treatments for cancer and ... of its previously announced underwritten public offering of ... public offering price of $2.00 per share, before ... expenses payable by Sorrento.  The net proceeds to ...
(Date:4/19/2017)... N.J. , April 19, 2017  Novartis ... by the National Heart, Lung, and Blood Institute ... demonstrating that 58% of patients with treatment-naïve severe ... months when treated with eltrombopag at the initiation ... . The study evaluated three sequential treatment groups, ...
Breaking Medicine Technology: