Navigation Links
Antidepressants: Benefit of SNRI is proven
Date:8/25/2009

The Institute for Quality and Efficiency in Health Care (IQWiG) was commissioned by the Federal Joint Committee (G-BA) to investigate whether patients with depression benefit from taking drugs belonging to the selective serotonin and norepinephrine reuptake inhibitor (SNRI) drug class. Up till now, 2 of these drugs have been approved as antidepressants in Germany: venlafaxine and duloxetine. The Institute published its final report on 18 August. According to this report, the benefit of both drugs has been proven compared to a sham drug (placebo): patients respond better to the therapy and suffer less from the symptoms of depression. Moreover, there are indications that both drugs protect against relapse in addition to alleviating symptoms.

Interplay of biological and psycho-social factors

There are various assumptions about when and how depression occurs. The possible causes and influencing factors are manifold. What is not disputed is that the complete clinical picture of depression is the result of a complex interplay of biological and psycho-social factors. There are indications that a modification or reduction in the transfer of certain messenger substances in the central nervous system plays a part. This is where most drug therapies start their effect. The comparatively new SNRI drug class is intended to influence two of these messenger substances (neurotransmitters) by inhibiting the reuptake of serotonin and norepinephrine.

Manufacturers provide unpublished data

IQWiG and its external experts found a total of 80 clinical trials that could be included in the assessment. Sixteen compared duloxetine (manufacturer: Lilly) with a sham drug or another antidepressant, 62 tested venlafaxine (manufacturer: Wyeth) in the same way, 2 trials compared the 2 drugs directly with each other. The manufacturers of both the drugs investigated (Lilly and Wyeth) provided a great deal of unpublished data.

In these trials
'/>"/>

Contact: Dr. Anna-Sabine Ernst
info@iqwig.de
49-022-135-6850
Institute for Quality and Efficiency in Health Care
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Only Severely Depressed Benefit From Antidepressants: Study
2. Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
3. Ambulatory oxygen rarely a benefit in COPD patients without resting hypoxemia
4. Discovery of sugar sensor in intestine could benefit diabetes
5. Study shines more light on benefit of vitamin D in fighting cancer
6. Vitamin Es lack of heart benefit linked to dosage
7. Practice-based intervention has sustained benefits for children and families
8. Manic phase of bipolar disorder benefits from breast cancer medication
9. Medicare Prescription Drug Benefit, Nonprofit Hospitals, Ambulatory Surgery Centers, Statistical Methods, and Pay-For-Performance Highlighted In the Latest INQUIRY Journal
10. Scientists highlight benefits of genetic research in sport, but warn of ethical concerns
11. The Butterfly Ball to Benefit Lung Association
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2015)... 2015 The new http://www.carsonenergy.com ... investors should consider oil and gas investing, the substantial ... are drilled, industry news, IRA investing, definitions and acronyms, ... of knowledge and experience is now in one central ... be able to access 24 hours a day, 7 ...
(Date:5/27/2015)... CURE® Magazine and the Bladder ... advance research, provide information and support, and raise awareness ... fifth most common type of cancer, which begins when ... out of control. , “CURE Magazine provides guidance ... the cancer experience through digital and print publications, live ...
(Date:5/27/2015)... May 27, 2015 Difass USA, a ... the U.S. with its first three flagship products, Dormiva™, ... purchase nationwide through http://www.difassusa.com . , A ... and productivity, but some people struggle with getting the ... is a sleep aid designed to help you fall ...
(Date:5/27/2015)... Cincinnati, Ohio (PRWEB) May 27, 2015 Cincinnati ... Education & Research for Veterans (CERV) Foundation is proud to ... information fair for women Veterans June 11 at the Freedom ... Reporter Karin Johnson will be the emcee. , This ... and devotion to the nation. The banquet is free ...
(Date:5/27/2015)... Francisco, CA (PRWEB) May 27, 2015 With ... a total communication environment where the message is not only ... a toy, drawing, or virtually any motivating image. This award-winning ... has to offer. , Now, using InnerVoice Sender ... messages can be sent to a learner remotely for no ...
Breaking Medicine News(10 mins):Health News:Carson Energy Launches Next Generation Investor Website 2Health News:CURE® Magazine and Bladder Cancer Advocacy Network Align to Increase Awareness of Fifth Most Common Type of Cancer 2Health News:CURE® Magazine and Bladder Cancer Advocacy Network Align to Increase Awareness of Fifth Most Common Type of Cancer 3Health News:Supplement Brand Difass USA Launches in the U.S. with Three Flagship Products Designed to Bring Balance Back to Your Life 2Health News:Cincinnati VA Women’s Health Clinic Celebrates Women Veterans at Awards Banquet 2Health News:Newly Released: InnerVoice Sender App Ups the Ante in Communication Technology for Autism with Remote Prompting 2Health News:Newly Released: InnerVoice Sender App Ups the Ante in Communication Technology for Autism with Remote Prompting 3Health News:Newly Released: InnerVoice Sender App Ups the Ante in Communication Technology for Autism with Remote Prompting 4
... , INDIANAPOLIS , Jan. 13 ... to announce it has received a "2010 Diversity Leader Award®" ... for demonstrating outstanding diversity communication practices during the past ... nation,s leaders in diversity and inclusion practices and has received ...
... The Day ... minimal incisions and a strong muscular suturing technique designed to provide significant facial appearance age ... ... plastic surgeon Dr. Phillip Langsdon is proud to announce "Day Lift.", , ,The economic ...
... ... advertising executive launches RedSquare360 to accommodate manufacturers, and web retailers, growing demands for 3D ... to help ecommerce clients increase conversion rates. , ... (PRWEB) January 13, 2010 -- Online retailers know the ...
... ... now supports Red Hat Enterprise Linux.,Djigzo is free and open source and can be downloaded ... packages for Ubuntu Linux, Red Hat and CentOS. A ready to run "Virtual Appliance" ... ...
... , ... The Environmental Protection Agency has designated January as National Radon Action ... gas is responsible for approximately 20,000 deaths in the U.S. and ... all lung cancer deaths.  Statistically, radon is the leading cause of ...
... , WASHINGTON , ... issued the following statement today on a ... nation,s largest insurance companies funneled between $10 ... Chamber of Commerce to fund deceptive television ads ...
Cached Medicine News:Health News:WellPoint, Inc. Receives 2010 Diversity Leader Award(R) 2Health News:WellPoint, Inc. Receives 2010 Diversity Leader Award(R) 3Health News:Economy Has Patients Looking For Less Costly Ways To Enhance Appearance Says Dr. Phillip Langsdon, MD, FACS 2Health News:360 Images Give Online Consumers A Product 'Demo' Before Purchasing. 2Health News:360 Images Give Online Consumers A Product 'Demo' Before Purchasing. 3Health News:Djigzo, an Open Source Email Encryption Provider, Today Announced That the Company's Encryption Gateway Now Supports Red Hat Linux 2Health News:Radon Gas Identified as America's Leading In-Home Killer; EPA Takes Action to Prevent 20,000 U.S. Cancer Deaths Each Year 2Health News:Radon Gas Identified as America's Leading In-Home Killer; EPA Takes Action to Prevent 20,000 U.S. Cancer Deaths Each Year 3Health News:Pelosi: 'Insurance Industry Has Spent Millions of Dollars on Wrong Side of History' by Secretly Funding Deceptive Ads 2
(Date:5/27/2015)... JOSE, Calif. , May 27, ... (NASDAQ: MXIM ) makes it ... sensor and to monitor or control ... the DS28E80 gamma-radiation-resistant, nonvolatile (NV) 1-Wire® ... for DS28E80: http://www.maximintegrated.com/en/products/digital/memory-products/DS28E80.html ...
(Date:5/27/2015)... WINNIPEG, Manitoba , May 27, 2015 /PRNewswire-USNewswire/ ... American customers, the Canadian International Pharmacy Association ... prescription medications online from licensed Canadian pharmacies. Approximately 64% ... health maintenance medications from a non-U.S. pharmacy due ... medications are not covered under their insurance plan.   ...
(Date:5/27/2015)... , May 27, 2015  Genomic Health, Inc. (Nasdaq: ... Operating Officer and Chief Financial Officer, will present at the ... City on Monday, June 1 at 8:30 a.m. ... subsequently archived webcast of the presentation, go to the  Investor ... .  Please connect to the web site at least 15 ...
Breaking Medicine Technology:Gamma-Radiation-Resistant Memory Provides Calibration and Protects from Unsanitary Reuse in Medical Disposables 2Gamma-Radiation-Resistant Memory Provides Calibration and Protects from Unsanitary Reuse in Medical Disposables 3Canadian International Pharmacy Association (CIPA) Survey of Americans Finds 64% Purchase Medications from Canada Due to Affordability 2Canadian International Pharmacy Association (CIPA) Survey of Americans Finds 64% Purchase Medications from Canada Due to Affordability 3Genomic Health to Present at the Jefferies 2015 Global Healthcare Conference 2Genomic Health to Present at the Jefferies 2015 Global Healthcare Conference 3
...
... Instant-View LH Ovulation Predicting Test is a ... Luteinizing Hormone (hLH) in human urine to ... regulated by the elevation of human luteinizing ... the period starts, hLH has a brief, ...
... The Shandon Varistain 24-4 is ... designed to offer simplicity and ... staining applications. It is desinged ... and continuous throughput. The ...
The Shandon Linistain GLX Linear Stainer is an economical mid-size linear stainer featuring 28 staining stations and a heater/dryer with fume control by a charcoal filter....
Medicine Products: