Navigation Links
Antidepressant Tied to Dangerous Heart Rhythm, FDA Says
Date:8/24/2011

WEDNESDAY, Aug. 24 (HealthDay News) -- High doses of the popular antidepressant Celexa can cause potentially fatal abnormal heart rhythms and should no longer be prescribed to patients, the U.S. Food and Drug Administration said Wednesday.

Doses of Celexa (citalopram hydrobromide) greater than 40 milligrams a day can cause changes in the electrical activity of the heart, which can lead to abnormal heart rhythms, including a potentially deadly arrhythmia known as Torsade de Pointes, according to the agency.

Patients at high risk for changes in the electrical activity of the heart include those with pre-existing heart conditions (including congestive heart failure) and those prone to low levels of potassium and magnesium in the blood, the FDA said.

Even though studies have not found that doses higher than 40 mg a day offer any benefits to patients with depression, Celexa's drug labeling previously stated that some patients may require a dose of 60 mg a day, the agency noted.

The label has been revised to include the new dosage limit as well as information about the potential for abnormal heart electrical activity and rhythms.

Celexa belongs to a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs), which also include widely used medications such as Paxil, Prozac and Zoloft.

More information

The American Academy of Family Physicians has more about antidepressants.

-- Robert Preidt

SOURCE: U.S. Food and Drug Administration, news release, Aug. 24, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Americans Use of Antidepressants On the Rise: Study
2. Certain Antidepressants Linked to Falls in Nursing Homes
3. Two Antidepressants Given to Dementia Patients Ineffective: Study
4. Research reveals that 10 percent of middle-aged Europeans are on antidepressants
5. UT Southwestern researchers uncover why ketamine produces a fast antidepressant response
6. Common Painkillers May Blunt Antidepressants
7. Antidepressants may not improve all symptoms of depression, UT Southwestern researchers find
8. U. Iowa study suggests antidepressants aid physical recovery in stroke
9. Study Hints at Link Between Antidepressants and Heart Trouble
10. Antidepressants linked to thicker arteries
11. New model for probing antidepressant actions
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antidepressant Tied to Dangerous Heart Rhythm, FDA Says
(Date:7/27/2017)... ... July 27, 2017 , ... Healthy eating isn’t always easy. Currently, more than 80 percent ... time, many Americans overeat refined grains and sugar. This trend may help explain why the ... the U.S. are obese. , As a culture, we seem to have food on the ...
(Date:7/27/2017)... ... July 27, 2017 , ... Cremations recently surpassed traditional ... Directors Association, this trend is expected to continue with over 70% of Americans projected ... growing demand for new innovations that enable families to celebrate the life of a ...
(Date:7/26/2017)... ... July 26, 2017 , ... Written By: Ashley D. Beall, ... in drug therapy for patients living with relapsing and primary multiple sclerosis that ... cell targeted therapy that has been proven to significantly reduce signs of disease ...
(Date:7/26/2017)... ... ... It may be hard to imagine that the basic necessities that developed countries ... that many developed countries consider rare or eradicated, like measles, are still a rite ... an upcoming segment of "Success Files", actor Rob Lowe will introduce a new segment ...
(Date:7/26/2017)... ... July 26, 2017 , ... ... the cloud ; today announced the availability of its latest data protection solution ... use control console for Data Discovery, Classification, Encryption and Digital Rights Management; GTB ...
Breaking Medicine News(10 mins):
(Date:7/13/2017)... 2017 RK Logistics Group, Inc. was awarded ... its Fremont, CA headquarters facility where ... and San Jose for hi-tech, pharmaceutical ... , with its Fremont Innovation District, is excited to ... powerful resource to the hundreds of biotech, pharma and biomed ...
(Date:7/12/2017)... 12, 2017  Eli Lilly and Company (NYSE: ... companies to resolve pending patent litigation in the U.S. District ... regarding the Cialis ® (tadalafil) unit dose patent. ... 2020. As part of the agreement, Cialis exclusivity is now ... "The unit dose patent for Cialis is valid ...
(Date:7/11/2017)... Md. , July 11, 2017  The global ... estimated revenues of approximately $394.1 million in 2016.  Although ... trend of solid growth, in particular as a result ... clinical practice, and the recent introduction of a significant ... need for less-invasive testing of tumor biomarkers to guide ...
Breaking Medicine Technology: