Navigation Links
Anticoagulant does not reduce rate of ischemic events among certain patients undergoing PCI
Date:9/1/2013

Use of the novel anticoagulant otamixaban did not reduce ischemic events compared with unfractionated heparin plus eptifibatide but increased bleeding among patients with nonST-segment elevation acute coronary syndromes undergoing a percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), according to a study published by JAMA. The study is being released early online to coincide with its presentation at the European Society of Cardiology Congress 2013

"Major progress has been made in the management of nonST-segment elevation [a certain pattern on an electrocardiogram] acute coronary syndromes (NSTE-ACS) because of the availability of potent combinations of oral antiplatelet agents, injectable anticoagulants, and increasing use of an invasive strategy. Nevertheless, the risk of adverse outcomes remains substantial, and there is no consensus on a single optimal injectable anticoagulant that can be used across the continuum of care from the emergency setting through revascularization (when applicable)," according to background information in the article. The synthetic intravenous drug otamixaban inhibits thrombin [an enzyme that acts on fibrinogen in blood causing it to clot] generation in a dose-dependent manner. A phase 2 trial showed a reduction in the combined outcome of death or myocardial infarction (heart attack) in patients treated with otamixaban compared with unfractionated heparin (UFH) plus eptifibatide (an antiplatelet drug) and showed similar bleeding rates with otamixaban at midrange doses.

Philippe Gabriel Steg, M.D., of the Universit Paris-Diderot, Sorbonne-Paris Cit, Paris, and investigators with the TAO trial compared the clinical efficacy and safety of otamixaban with that of unfractionated heparin plus eptifibatide in 13,229 patients with NSTE-ACS and a planned early invasive strategy. The trial was conducted at 568 active sites in 55
'/>"/>

Contact: Philippe Gabriel Steg, M.D.
gabriel.steg@bch.aphp.fr
The JAMA Network Journals
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Huntingtons Disease Linked to Reduced Cancer Risk in Study
2. BMC study shows diverting passengers to elevators could help reduce falls at Logan Airport
3. Decision guide reduced uncertainty over breast cancer prevention, study finds
4. Scoliosis Treatment Might Reduce Need for Surgeries
5. Exercise helps smokers to quit smoking, to remain smoke-free and to reduce the risk of death
6. Additional blood pressure screening may reduce incidence of CVD events and death by up to 3 percent
7. Groundbreaking Nigeria summit results in major commitment to reduce child deaths
8. Soy-based S-equol supplement reduces hot flash frequency, muscle & joint pain in US women
9. Use of dedicated pediatric imaging departments for pediatric CT reduces radiation dose
10. Automated breast ultrasound dramatically reduces physician interpretation time
11. Diabetic retinopathy research could reduce screening costs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... Aid in Recovery, a full service ... regarding a recent bill introduced in the ... current legislator and retired police general. In House Bill ... offenders, rather than imprisonment. Aid in Recovery points to ... for the drug addiction epidemic. , The bill, introduced ...
(Date:8/21/2014)... August 22, 2014 Benefiting from ... for medical expenses, the Chinese orthopedic instrument market ... presenting a CAGR of 19.2% during 2009-2013. Trauma ... product segments of orthopedic instruments in China, of ... market share in 2013. , Being optimistic about ...
(Date:8/21/2014)... The natural loss of collagen, or slower production ... of skin. Using products to boost collagen and nurture ... has lost about 15% of it collagen production and by ... founder of Sublime Beauty®. "Collagen holds up the structure ... know what happens." , Collagen in fact makes up more ...
(Date:8/21/2014)... Florida Hospital Zephyrhills is the ... the only in the Tampa Bay area to ... Olympus Endoalpha Universal Platform for surgical endoscopy. The ... specialties, and provides the hospital a standardized solution ... and patient care. Surgical endoscopy systems, through the ...
(Date:8/21/2014)... Recently, Skmen.com, a distinguished garment supplier, has ... girls’ casual dresses . From today until August 31, ... percent off) when they are shopping at the company’s online ... are according to the newest quality standards; they are guaranteed ... casual dresses, worldwide ladies can also access the other cheap ...
Breaking Medicine News(10 mins):Health News:Proposed Legislature in the Philippines Highlights the Need for Rehabilitation, Not Incarceration, for Drug Users, Says Aid in Recovery 2Health News:Proposed Legislature in the Philippines Highlights the Need for Rehabilitation, Not Incarceration, for Drug Users, Says Aid in Recovery 3Health News:China Orthopedic Instrument Industry Report, 2014-2017 Now Available at ChinaMarketResearchReports.com 2Health News:China Orthopedic Instrument Industry Report, 2014-2017 Now Available at ChinaMarketResearchReports.com 3Health News:China Orthopedic Instrument Industry Report, 2014-2017 Now Available at ChinaMarketResearchReports.com 4Health News:4 Skincare Products That Boost and Nurture Collagen on Sale at Sublime Beauty® 2Health News:4 Skincare Products That Boost and Nurture Collagen on Sale at Sublime Beauty® 3Health News:Florida Hospital Zephyrhills is Elevating Healthcare by Offering the First Olympus Fully-Integrated HD Operating Room in Pasco County 2Health News:Florida Hospital Zephyrhills is Elevating Healthcare by Offering the First Olympus Fully-Integrated HD Operating Room in Pasco County 3Health News:Charming Girls’ Casual Dresses Now Released by Distinguished Garment Company Skmen.com 2
... A recently completed international multi-center clinical trial has found ... and effective treatment to suppress herpes simplex virus-2 (HSV-2), ... does not reduce the risk of HIV transmission when ... , The majority of people with HIV ...
... 8 AMDL Inc. (NYSE ... operations in China, announced today its JJB wholly foreign-owned ... approval from the Chinese State Food and Drug Administration ... manufacturing line which is specifically used to produce the ...
... VIENNA, Va., May 8 Prematics Inc. has selected ... company,s chief medical officer and senior vice president of ... with the company,s health care enterprise clients, helping them ... communicate with providers and members at the point of ...
... at home is safe, effective and more convenient, researchers ... Home-based ultraviolet B (UVB) therapy for psoriasis is as ... Dutch researchers report. , Receiving UVB treatment at a ... inflammatory skin condition because a course of treatment typically ...
... Series of Nationwide Investor MeetingsTUCSON, Ariz., May 8 ... today announced that, in connection with management,s upcoming meetings with ... and Exchange Commission its Spring 2009 Investor Presentation. Stockholders ... at the SEC,s website at http://www.sec.gov ...
... A Recession Is the Best Time to ... recession than at any other time, according to research. ... millionaires around the world. They,ve all overcome major obstacles ... low school grades, and childhood poverty. With their backs ...
Cached Medicine News:Health News:Herpes medication does not reduce risk of HIV transmission 2Health News:Herpes medication does not reduce risk of HIV transmission 3Health News:Herpes medication does not reduce risk of HIV transmission 4Health News:AMDL Inc.'s JJB Plant Receives Production Approval From Chinese State Food and Drug Administration (SFDA) 2Health News:Prematics Names S. Michael Ross Chief Medical Officer and Senior Vice President of Business Development 2Health News:Prematics Names S. Michael Ross Chief Medical Officer and Senior Vice President of Business Development 3Health News:Psoriasis Patients Happy With Home-Based Treatment 2Health News:Providence Service Corporation Makes Its Spring 2009 Presentation Publicly Available 2Health News:Providence Service Corporation Makes Its Spring 2009 Presentation Publicly Available 3Health News:Providence Service Corporation Makes Its Spring 2009 Presentation Publicly Available 4Health News:Providence Service Corporation Makes Its Spring 2009 Presentation Publicly Available 5Health News:Providence Service Corporation Makes Its Spring 2009 Presentation Publicly Available 6Health News:Do a Show on Money, Marriage and Mental Health in a Tough Economy 2
(Date:8/21/2014)... Aug. 21, 2014 Professional Compounding Centers ... medicine by awarding the three best scientific presentations ... (EuPFI) conference . The Formulating Better Medicines ... in Athens, Greece , includes ... and professionals, from which three winners will be ...
(Date:8/21/2014)... , Aug. 21, 2014  SI-BONE, Inc. ( ... company that pioneered the use of the iFuse Implant ... indicated for fusion of the sacroiliac (SI) joint, announced ... an update to its Lumbar Fusion Medical Policy No. ... fusion procedure.  The policy states that the fusion procedure, ...
(Date:8/20/2014)... , Aug. 20, 2014  The National Association ... latest results achieved by the real-time, pseudoephedrine (PSE) ... National Precursor Log Exchange (NPLEx), automatically blocks unlawful ... down meth offenders and make arrests. Data released ... Indiana blocked the sale of more ...
Breaking Medicine Technology:Professional Compounding Centers of America will award top poster-session winners at European Paediatric Formulation Initiative in Athens 2SI-BONE, Inc. Announces Positive Coverage Decision by Priority Health 2SI-BONE, Inc. Announces Positive Coverage Decision by Priority Health 3Indiana's Stop-Sale System Achieves Significant Results In Battle Against Meth 2
... NEW YORK, Oct. 18 Reportlinker.com announces that ... its catalogue: Global Wound Care ... This report analyzes the worldwide ... The major product segments analyzed are Traditional {Wound ...
... Hanger Orthopedic Group, Inc. (NYSE: HGR ... the quarter ended September 30, 2010, an increase of ... prior year. Preliminary adjusted diluted earnings per share, which ... and cost incurred in connection with the pending acquisition ...
Cached Medicine Technology:Reportlinker Adds Global Wound Care Products Industry 2Reportlinker Adds Global Wound Care Products Industry 3Reportlinker Adds Global Wound Care Products Industry 4Reportlinker Adds Global Wound Care Products Industry 5Reportlinker Adds Global Wound Care Products Industry 6Reportlinker Adds Global Wound Care Products Industry 7Reportlinker Adds Global Wound Care Products Industry 8Reportlinker Adds Global Wound Care Products Industry 9Reportlinker Adds Global Wound Care Products Industry 10Reportlinker Adds Global Wound Care Products Industry 11Reportlinker Adds Global Wound Care Products Industry 12Reportlinker Adds Global Wound Care Products Industry 13Reportlinker Adds Global Wound Care Products Industry 14Reportlinker Adds Global Wound Care Products Industry 15Reportlinker Adds Global Wound Care Products Industry 16Reportlinker Adds Global Wound Care Products Industry 17Reportlinker Adds Global Wound Care Products Industry 18Reportlinker Adds Global Wound Care Products Industry 19Reportlinker Adds Global Wound Care Products Industry 20Reportlinker Adds Global Wound Care Products Industry 21Reportlinker Adds Global Wound Care Products Industry 22Reportlinker Adds Global Wound Care Products Industry 23Reportlinker Adds Global Wound Care Products Industry 24Hanger Orthopedic Group Announces Preliminary Third Quarter Revenue and Earnings 2Hanger Orthopedic Group Announces Preliminary Third Quarter Revenue and Earnings 3Hanger Orthopedic Group Announces Preliminary Third Quarter Revenue and Earnings 4
4 mm disposable bevel blade. Malleable shafts. Flat spot on handle designed to guide knife in perforation....
Straight 8 mm downcutting Royce blade. Can be placed in closed handle for protection. Rigid handle when folded and locked. Straight 8 mm downcutting blades. Handle length folded 109 mm, 4.3 inches....
Duckbill type, sharp. 3 mm x 8 mm curved blade. Octagonal handle....
10 mm wide tip....
Medicine Products: