Navigation Links
Anticlotting drug found to be safe in sickle cell patients
Date:10/11/2007

CHAPEL HILL - An intravenous blood thinner widely used in patients with acute coronary syndromes and during coronary artery stent placement appears to be safe in patients with sickle cell disease and may have beneficial anti-inflammatory effects, a small study at the University of North Carolina at Chapel Hill School of Medicine has found.

We have tested a potentially promising drug in sickle cell patients, and the drug appears to be well tolerated. This gives us the impetus to go ahead with further studies of eptifibatide in these patients, said Dr. Leslie V. Parise, department chair and professor of biochemistry and biophysics at the UNC-Chapel Hill School of Medicine.

The hallmark of sickle cell disease is malformed red blood cells that can cause sudden painful episodes when they block small blood vessels. However, sickle cell patients are also at increased risk of developing multiple other complications, including strokes, lung complications and pulmonary hypertension.

The most frequent manifestations of sickle cell disorders are anemia and pain episodes. The episodic exacerbation of pain, often called crises, is unpredictable and may occur often in some patients.

The only drug presently approved for the treatment of sickle cell disease is hydroxyurea, which has been shown to reduce the frequency of painful episodes.

Parise emphasized the need for further study. We did not test this drug in patients who are in crisis, and we cannot recommend that doctors prescribe this drug for sickle cell patients at this time, she said.

The results of the study were published online (Oct. 6) in the British Journal of Haematology.

The researchers gave intravenous infusions of eptifibatide (brand name Integrilin) to four patients with sickle cell anemia who were not experiencing pain episodes. They did well clinically. They did not experience any deleterious changes in their blood tests or have a pain episode
'/>"/>

Contact: Les Lang
LLANG@MED.UNC.EDU
919-843-9687
University of North Carolina at Chapel Hill
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Distraction therapy found very effective in postoperative patients
2. Genetic differences found between Male and Female brains
3. Breastfeeding not found to have an impact on weight of the child.
4. Common Cold Found to Fight Cancer Cells
5. Mentally Demanding Jobs Found To Reduce The Risk Of Alzheimer’
6. Caffeine Found To Worsen Diabetes
7. Drug Found To Bring Relief For Individuals With Early Parkinson’
8. Environmental Factors Found To Have An Impact On The Sex of A Child
9. New molecule to treat brain disorders found
10. Higher Rates Of Diabetes Found Among The Poor
11. Antioxidants found in chocolates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... there are only 24 hours in a day, that doesn’t seem ... time within their busy schedules for exercise and fitness. Fortunately, one ... get in shape. Here are five ways you can reach your ... Up Your Commute , Consider riding a bike or taking the ... daily routine. If you must use your car to get to ...
(Date:10/22/2014)... By Steven Reinberg ... -- Infants who quickly add weight and length may be ... study suggests. In adults, certain genes have been linked ... promote proportionate gains in fat and lean muscle, the researchers ... be heavier and taller. By ages 2 and 3, however, ...
(Date:10/22/2014)... Maureen Salamon HealthDay ... A crucial part of conventional in vitro fertilization (IVF) -- ... instead take place in a device inside the vagina, new ... contend that the device, called an INVOcell, might sharply cut ... also make the technology more accessible to those who don,t ...
(Date:10/20/2014)... 2014 The newly updated Worldwide Medical ... thousands of facts, figures and forecasts on the global ... sector forecast categories the Worldwide Medical Market Forecasts ... national views on the worldwide medical market to reveal ... gives you data for 2010-2019, covering each country market ...
(Date:10/20/2014)... York, NY (PRWEB) October 20, 2014 ... based non-profit organization that helps New Yorkers living ... positive changes toward health, housing, recovery and self-sufficiency. ... have transformed the local community through their tireless ... Director, Marc Shapses , has been selected ...
Breaking Medicine News(10 mins):Health News:HealthGuideMD Presents Ways to Improve Your Exercise and Fitness 2Health News:Tall, Heavy 1-Year-Olds May Be at Risk for Obesity Later, Study Finds 2Health News:Experimental Infertility Treatment Seems Effective, Cheaper 2Health News:Experimental Infertility Treatment Seems Effective, Cheaper 3Health News:Experimental Infertility Treatment Seems Effective, Cheaper 4Health News:Worldwide Medical Market Forecasts to 2019 a New Research Report Added to ReportsnReports.com 2Health News:Worldwide Medical Market Forecasts to 2019 a New Research Report Added to ReportsnReports.com 3Health News:Worldwide Medical Market Forecasts to 2019 a New Research Report Added to ReportsnReports.com 4Health News:Savills Studley's Marc Shapses To Be Honored as 2014 "Positive Changemaker" by ASCNYC 2Health News:Savills Studley's Marc Shapses To Be Honored as 2014 "Positive Changemaker" by ASCNYC 3
... internal report that some patients might die due to ... publicize the flaw to retain // acceptability, company records ... in mid-2002 that the consequences of the defibrillator’s electrical ... assessment, the company kept selling potentially flawed devices and ...
... live bird flu vaccine for dual protection against bird flu ... in China. This move is further anticipated to lead ... ,More than 1-billion units of the vaccine are believed ... supplement to the already existing vaccines, according to Jia Youling, ...
... manufactured for the first time first indigenous Tetanus and Diphtheria ... Td-Vac and will combat the deadly diphtheria and tetanus among ... existing TT (Tetanus) vaccine, which is normally administered after an ... TT vaccine costs Rs.6.50. Revenues of Rs 5-6 crore is ...
... state government of Jharkhand has given health the status ... health sector to receive all facilities provided under the ... receive incentives and infrastructure support. ,The government ... life to the health sector in state, where half ...
... that can detect the Hepatitis C virus using saliva instead ... University Medical Centre // in Israel carried out their ... blood must be passed through a machine to filter out ... have a high incidence of Hepatitis C. ,The researchers ...
... reports that television soaps or serials give a false picture ... compiled 10 years data of sufferings felt // by ... recovery shown in television soaps is not true as the ... died during coma for instance, compared with 50% upwards in ...
Cached Medicine News:Health News:Guidant sold defective defibrillators with full knowledge 2Health News:Guidant sold defective defibrillators with full knowledge 3
(Date:10/22/2014)... VERNE, Calif. , Oct. 22, 2014 /PRNewswire/ ... readiness products, has developed APLS ® Body ... that minimizes the spread of bacteria and virus ... APLS Body Guard Bio features a rugged, ... finished edges that create a leak-proof inner chamber ...
(Date:10/22/2014)... Inc. (NYSE: CRY ), a leading medical ... vascular surgery, announced today that James Patrick (Pat) ... elected to the Company,s Board of Directors, effective October ... Executive Chairman of CryoLife, stated, "Since joining the Company in ... who is well positioned to maximize CryoLife,s potential.  His ...
(Date:10/22/2014)... 2014   BioNano Genomics , the genome ... centers to purchase an Irys™ System . Among ... Institute (NCI), NIH Intramural Sequencing Center (NISC) and Genoscope ... a comprehensive view of a genome was a ... not deliver the scalability or reliability to detect ...
Breaking Medicine Technology:New, State-Of-The-Art Body Bag Minimizes The Spread Of Bacteria And Virus 2Pat Mackin Joins CryoLife Board of Directors 2Pat Mackin Joins CryoLife Board of Directors 3BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 2BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 3
... Blood America, Inc . ( http://www.cordblood-america.com ) (OTC Bulletin Board: ... cell preservation company focused on bringing the life saving ... today a Special Meeting of its shareholders on April 21, ... split of one share for each 500 outstanding shares and ...
... PRO-DEX, INC. (Nasdaq: PDEX ) today announced ... ended December 31, 2010. Sales for the ... from $5.7 million for the corresponding quarter in 2009, resulting ... products to its largest customer, and from growth in sales ...
Cached Medicine Technology:Cord Blood America Announces Special Shareholder Meeting 2Cord Blood America Announces Special Shareholder Meeting 3Pro-Dex, Inc. Announces Fiscal Second Quarter and Six Month Results 2Pro-Dex, Inc. Announces Fiscal Second Quarter and Six Month Results 3Pro-Dex, Inc. Announces Fiscal Second Quarter and Six Month Results 4Pro-Dex, Inc. Announces Fiscal Second Quarter and Six Month Results 5Pro-Dex, Inc. Announces Fiscal Second Quarter and Six Month Results 6Pro-Dex, Inc. Announces Fiscal Second Quarter and Six Month Results 7
Dilator...
Microscopic needle holder, curved...
Made with navy nylon reinforced vinyl for superior strength and ease of cleaning. Optional colors available are teal, royal, red, purple, and maroon nylon stain resistant material....
This apron was designed by Pulse Medical-RCI for optimal protection. Your comfort is also a primary concern so a wide support belt and shoulder pads are standard. When properly fitted, an overlapping...
Medicine Products: