Navigation Links
Antibody production gets confused during long-term spaceflight
Date:5/19/2011

Bethesda, MDThe trip to Mars just got a little more difficult now that French researchers have discovered that antibodies used to fight off disease might become seriously compromised during long-term space flight. In a new report published online in the FASEB Journal (http://www.fasebj.org), the scientists show that antibodies produced in space are less effective than those produced on terra firma. The reduced effectiveness of antibodies makes astronauts more susceptible to illness, while increasing the danger posed by bacteria and viruses likely to coexist with wayfaring astronauts.

"We hope to find efficient pharmacological and/or nutritional countermeasures to alterations of the immune system that could be useful to astronauts and to people who have weak immune systems on Earth because of infections, aging, or chronic stress exposure," said Jean-Pol Frippiat, a researcher involved in the work from the Faculty of Medicine, Development and Immunogenetics at the Universit Henri Poincar-Nancy, Vanduvre-ls-Nancy, France.

To make their discovery, Frippiat and colleagues conducted studies using three groups of amphibians. Amphibians were chosen for the work because they use the same cellular mechanisms to produce antibodies as humans do. The first group of amphibians was immunized in space, the second was immunized on Earth, and the third was not immunized at all. Comparison of the antibodies produced revealed that the quality of the antibodies generated by the group immunized in space was decreased. This suggests that spaceflight conditions alter the immune system and affect its ability to protect against infections and tumors, posing a serious risk for astronauts.

"This paper shows that somatic hypermutation occurs at a lower frequency in spaceflight and brings together yet more evidence that the immune system is dependent on gravity," said Millie Hughes-Fulford, Ph.D., NASA Science Astr
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Tiny antibody fragments raised in camels find drug targets in human breast cancer cells
2. Tufts receives patent for antibody treatment against hemolytic uremic syndrome
3. HJF signs distribution agreement for antibody to evaluate prostate cancer
4. Antibody Linked to Allergies on the Rise
5. Antibody therapy lengthens survival of metastatic melanoma patients in large clinical trial
6. Fox Chase clinical trial tests first of its kind antibody
7. European Society of Human Reproduction and Embryology Annual Meeting, July 3-6, 2011, Stockholm
8. Home urine test measures insulin production in diabetes
9. Cigarette Smoke Fuels Mucus Production in People With Bronchitis
10. Cocaine production increases destruction of Colombias rainforests
11. Biologists discover control center for sperm production
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... Pass, OR (PRWEB) August 20, 2014 ... parents are urged to become educated about eye health ... eye examined. One frequently overlooked eye condition that must ... the Sharon Kleyne Hour Power of Water radio show, ... young children increasing exponentially, childhood dry eye is becoming ...
(Date:8/20/2014)... DC (PRWEB) August 20, 2014 Hope ... Heart, Give Hope® Celebration to be hosted in Washington, ... and Navy Club. This signature event honors the courage ... families of the fallen. Proceeds from the Got Heart, ... a national nonprofit dedicated to restoring a sense of ...
(Date:8/20/2014)... Building on growing success by ... stage iii and iv pressure ulcers with extremely ... 90%. A company spokesperson commented that these accuracy ... academic settings. The resulting capabilities can be extended ... conditions to help providers avoid financial losses while ...
(Date:8/20/2014)... 2014 Blaine Labs®, the creators ... RevitaDERM® Psoriasis Treatment to ease the redness, ... This all-in-one product was created to treat, moisturize, ... is powered by coal tar and formulated to ... effective ingredient. , RevitaDERM® Psoriasis Treatment is ...
(Date:8/20/2014)... Diego, CA (PRWEB) August 20, 2014 AttorneyOne.com, ... all the latest information from the FDA on Sodium ... August 13, that one lot of Sodium Chloride IV 0.9%, ... due to the presence of particulate matter. Sodium Chloride ... electrolytes and as a priming solution in hemodialysis procedures. ...
Breaking Medicine News(10 mins):Health News:August is Children’s Eye Health Month, Exams Must Check for Pediatric Dry Eye 2Health News:August is Children’s Eye Health Month, Exams Must Check for Pediatric Dry Eye 3Health News:Hope For The Warriors Announces Got Heart, Give Hope Celebration in Washington, DC 2Health News:Jvion Achieves Benchmark Accuracy in Pressure Ulcer Prediction 2Health News:RevitaDERM® Psoriasis Treatment Now Available At Over 7,600 CVS/pharmacies 2Health News:Sodium Chloride IV 0.9% by Baxter Recalled: AttorneyOne Monitors and Keeps Consumers Informed 2
... permission with European medicine regulators to begin selling its new ... in the US last month, and comes slightly earlier than ... be one of GSK's most promising pipeline drugs as well ... the sales of the drug could cross 2 bln used ...
... world who get uncomfortable after a heavy meal here is ... have proven that eating 6-8 walnuts (approx.40g) after a rich ... triggered of in the walls of arteries after a highly ... the Oct. 17 issue of the Journal of the American ...
... given to bowel cancer patients before the surgical removal ... risk of recurrence to 1 %. The usual ... of recurrence is there and once reappeared, treatment is ... conducted an international study, to compare the effect of ...
... after irrigation water samples tested positive for E. coli ... relaxed its advisory against eating fresh spinach. ... detected after a secondary water source temporarily used to ... the water got contaminated is still not clear. ...
... challenges parenting stereotypes; Today’s parents boast about the numerous classes ... and the many talents they possess. Competitive parents in their ... ‘super-kids’ , often smother their children with an over-dose of ... gizmos , play stations, and game boys… and Oh boy, ...
... Around 45 Iraqi children have arrived in Bahrain to receive ... to arrive in the coming days as part of an ... move Sunday came in response to a call to help ... composer Naseer Shamma, who is the head of the newly ...
Cached Medicine News:Health News:Walnuts May Help Fight Fat and Keep Arteries Supple 2
(Date:8/19/2014)... Ohio , Aug. 19, 2014 Minimally ... medical device company, announced today that Mitsubishi ... laparoscopic and robotic visualization system in Japan ... for sale in Japan in ... is also the exclusive distributor for Karl Storz GMBH ...
(Date:8/19/2014)... YORK , Aug. 19, 2014  As ... around the country, Bernstein Liebhard LLP notes that ... can choose between a number of options that ... dangerous surgical instrument. According to a report published ... th , these options include a mini-laparotomy and ...
(Date:8/19/2014)... Aug. 19, 2014 Research and Markets ... Type of Material, by Technology, by Application & by Region- ... offering. The demand for membranes is estimated ... the market to $29.31 billion Membrane technology was ... such as water filtration and kidney dialysis. In modern times, ...
Breaking Medicine Technology:Minimally Invasive Devices and Mitsubishi Medical Japan Forge Exclusive Distribution Agreement 2As Morcellator Lawsuits Mount, Bernstein Liebhard LLP Notes Report Detailing Alternatives to Uterine Morcellation 2As Morcellator Lawsuits Mount, Bernstein Liebhard LLP Notes Report Detailing Alternatives to Uterine Morcellation 3Global Membranes (MF, RO, UF, Gas Separation, Dialysis, NF) Market - Forecasts to 2019 2
... YORK, July 13, 2011 Reportlinker.com announces ... available in its catalogue: ... 2011-2021 http://www.reportlinker.com/p0572968/Pharmaceutical-Wholesale-and-Distribution-Industry-World-Outlook-2011-2021.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Wholesali ... decade affect those activities? ...
... NATICK, Mass., July 12, 2011 RegenoCELL Therapeutics, Inc. ... F. Mongiardo, Chief Executive Officer, reported that plans are ... the United States and Europe for its stem cell ... Regenocell, Ltd., reported that it expects to begin marketing ...
Cached Medicine Technology:Pharmaceutical Wholesale and Distribution Industry: World Outlook 2011-2021 2Pharmaceutical Wholesale and Distribution Industry: World Outlook 2011-2021 3Pharmaceutical Wholesale and Distribution Industry: World Outlook 2011-2021 4Pharmaceutical Wholesale and Distribution Industry: World Outlook 2011-2021 5Pharmaceutical Wholesale and Distribution Industry: World Outlook 2011-2021 6Pharmaceutical Wholesale and Distribution Industry: World Outlook 2011-2021 7Pharmaceutical Wholesale and Distribution Industry: World Outlook 2011-2021 8Pharmaceutical Wholesale and Distribution Industry: World Outlook 2011-2021 9Pharmaceutical Wholesale and Distribution Industry: World Outlook 2011-2021 10Pharmaceutical Wholesale and Distribution Industry: World Outlook 2011-2021 11Pharmaceutical Wholesale and Distribution Industry: World Outlook 2011-2021 12Pharmaceutical Wholesale and Distribution Industry: World Outlook 2011-2021 13RegenoCELL Gives Second Half Update 2RegenoCELL Gives Second Half Update 3RegenoCELL Gives Second Half Update 4RegenoCELL Gives Second Half Update 5RegenoCELL Gives Second Half Update 6
... if it is not the Flu? Streptococcus ... bacterial "flu-like" infections. The easy-to-use, rapid, urine-based ... within the new 4 hour guidelines. Rapid ... improved patient outcomes and lower overall health ...
Single Use Loading Units with Titanium Staplers for use with MULTIFIRE ENDO TA™ 30 12 mm (Single Use Staplers with Titanium Staplers)....
Single Use Loading Units (SULU's) Knifeless for use with MULTIFIRE ENDO GIA™ 30 12 mm (Single Use Staplers with Titanium Staples)....
Single Use Loading Units (SULU's) with Titanium Staples for use with MULTIFIRE ENDO GIA™ 30 12 mm (Single Use Staplers with Titanium Staples)....
Medicine Products: