Navigation Links
Antibodies for new rotavirus vaccines
Date:7/17/2012

CSIRO has been contracted by PATH (Program for Appropriate Technology in Health) to produce antibodies on a large scale that will aid the development of new, safe, affordable and effective vaccines against rotavirus, a major cause of severe and fatal diarrhoea in young children worldwide.

Rotavirus kills nearly half a million children every year, 85 per cent of whom live in developing countries. The virus is one of the most common causes of hospital and emergency admissions for children under five in Australia.

Since the introduction of two rotavirus vaccines, Rotarix and RotaTeq, to Australia's National Immunisation Program in 2007, hospitalisations of children under five years of age due to rotavirus gastroenteritis have been reduced by over 70 per cent.

PATH, an international not-for-profit organisation, is working to increase access to and effectiveness of existing commercial rotavirus vaccines worldwide, while also working with emerging-country vaccine manufacturers to speed up the development of safe, effective, and more affordable new rotavirus vaccines.

"CSIRO will produce a large quantity of antibodies specific to the strains of rotavirus that are in the vaccines our partners are developing, which will serve as important material for our project," said Dr Georges Thiry, director of PATH's rotavirus vaccine development project.

"New vaccines and suppliers will increase the availability of rotavirus vaccines and increase competition, which in turn will help make all of the rotavirus vaccines on the market more affordable and accessible to the world's most vulnerable children."

Dr George Lovrecz, group leader for CSIRO's protein production and fermentation group, is confident that CSIRO's expertise from the tissue culture and purification teams will deliver excellent results.

"We are proud to be assisting this groundbreaking project that is working to help save the lives of children in the world's poorest countries," he said.

CSIRO will use their recombinant protein production facility in Clayton, Victoria, for the large-scale production of the antibodies.

"This unique, state-of-the-art facility will allow us to produce enough antibodies to supply PATH's partners for the next five years," said Dr Lovrecz.

"We will be producing six antibodies that will be used to test the quality of the rotavirus vaccines being developed."

The antibodies, originally prepared by Dr Carl Kirkwood from the Murdoch Childrens Research Institute, will be used by PATH's manufacturing partners in China, Brazil, and India and by the United States' National Institutes of Health.


'/>"/>

Contact: Merrin Fabre
Merrin.Fabre@csiro.au
61-395-458-362
CSIRO Australia
Source:Eurekalert

Related medicine news :

1. Antibodies from rabbits reduce risks associated with unrelated donor stem cell transplantation
2. Antibodies from rabbits reduce risks associated with
3. Antibodies reverse type 1 diabetes in new immunotherapy study
4. ACP Immunization Advisor app makes it easier for doctors to identify vaccines for patients
5. Control gene for conveyor belt cells could help improve oral vaccines, treat intestinal disease
6. OHSU Oregon National Primate Research Center develops new, safer method for making vaccines
7. World Health Assembly endorses new plan to increase global access to vaccines
8. Study: More Pre-Teens Get Vaccines When Middle Schools Require Them
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... ... February 08, 2016 , ... ... states in the U.S. require dental technicians to be certified or obtain continuing ... industry, NADL created the “What’s In Your Mouth?” campaign to inform dentists and ...
(Date:2/7/2016)... ... February 07, 2016 , ... Women's Excellence staff, in all four locations, wore ... Wear Red Day is the first Friday each February and a day to bring ... in 3 deaths among women each year – more than all cancers combined. Go ...
(Date:2/7/2016)... ... 2016 , ... Dr. Todd Hobgood , certificated in ... surgical expertise. Technically known as deoxycholic acid or previously as ATX-101, Kybella® ... for reduction of fat below the chin (aka the “double chin”). Medication side ...
(Date:2/6/2016)... ... ... US Sports Camps is proud to sponsor the Bay Area Disc Association's ... leaders, ultimate organizations, and coaches from around the US. The theme for this year’s ... of Youth and Education, describes this year YUCC as “an important conversation we must ...
(Date:2/6/2016)... , ... February 06, 2016 , ... Shark Finds ... announce the launch of a new DRTV campaign with Belly Bands. , Having a ... everything from sprays to puppy pads and find nothing works, get Belly Bands, ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... Feb. 8, 2016   GS1 US will ... guide them through GS1 Standards implementation to address the ... Unique Device Identification (UDI) rule. Scott ... Beth Gibson , senior director industry development, medical devices, ... director, GS1 US --> Scott ...
(Date:2/8/2016)... Feb. 8, 2016 Nueterra, the ... specialized in the development of equity partnerships ... it has divided its interests between two ... Capital will continue the founding company,s private ... operate a national system of integrated provider ...
(Date:2/8/2016)... Pa. , Feb. 8, 2016   ... November Research Group (NRG),s pharmacovigilance technology services ... system-related consulting services and an Oracle Argus Specialized ... services to Life Sciences companies. ... and expands HighPoint,s life sciences capabilities and provides ...
Breaking Medicine Technology: