Navigation Links
Antibiotics Linked to Retinal Detachment Risk
Date:4/3/2012

By Steven Reinberg
HealthDay Reporter

TUESDAY, April 3 (HealthDay News) -- People taking antibiotics called fluoroquinolones may be at a small risk of an eye condition called retinal detachment, a new study suggests.

These commonly prescribed antibiotics, used to fight a variety of bacterial infections, have been linked to other eye problems, including corneal perforations, optic neuropathy and retinal hemorrhages. But this is the first study that has linked them to retinal detachment, a serious medical emergency that may lead to blindness, the Canadian researchers said.

"These are powerful antibiotics, so they should only be used in patients who really need them, as many studies show they are inappropriately prescribed," said lead researcher Dr. Mahyar Etminan, an assistant professor of medicine at the Child and Family Research Institute of British Columbia in Vancouver.

"Patients who experience floaters or flashes of light in their visual field while taking these drugs should see an ophthalmologist to prevent possible retinal detachment," he added.

"Since this condition is serious and may lead to severe loss of visual acuity or even blindness, patients taking these drugs should be familiar with these signs," he said.

The report was published in the April 4 issue of the Journal of the American Medical Association.

For the study, Etminan's team analyzed records of almost 1 million patients who saw an ophthalmologist between January 2000 and December 2007.

Among these patients, more than 4,300 had a retinal detachment. The researchers paired each of these patients with 10 individuals who did not have the condition.

The investigators found that those suffering a retinal detachment were more likely to be near-sighted, have diabetes or have had cataract surgery.

In addition, 3.3 percent of those with a retinal detachment were taking fluoroquinolones, compared with 0.6 percent of those without the condition, the study authors noted.

However, there was no risk of retinal detachment among people who had taken the antibiotics recently or those who had taken them in the past, the study found.

And while current users of fluoroquinolones had a nearly five times higher risk of retinal detachment, the absolute risk was very small -- only 1 in 2,500, for any use of fluoroquinolones, they noted.

"This magnitude of risk seems small, but given that there are about 40,000,000 prescriptions written for these drugs in the U.S., it translates to around 4,000 new cases per year," Etminan said.

The study does not establish a cause-and-effect relationship between antibiotics and retinal detachment, only a weak association.

Commenting on the study, Dr. William Smiddy, a professor of ophthalmology at the University of Miami Bascom Palmer Eye Institute, said, "I don't believe it."

If the risk were real, you would expect to find people who had taken the antibiotics to have had the condition, but the study didn't find that, he said.

"It's not something we can discount, but it's hard to believe," Smiddy added. "It's not something I've even heard described, before this paper."

In addition, Smiddy noted that the study only suggests there may be a connection.

"Even if there is a risk, it's a low risk, so if you need a fluoroquinolone you should be on a fluoroquinolone," Smiddy said. "We don't want to throw the baby out with the bathwater."

More information

For more information on detached retina, visit the U.S. National Library of Medicine.

SOURCES: Mahyar Etminan, Pharm.D., M.Sc., assistant professor of medicine, Child and Family Research Institute, British Columbia, Vancouver, Canada; William Smiddy, M.D., professor of ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine; April 4, 2012, Journal of the American Medical Association


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Giant Eagle Pharmacy Free Antibiotics Program Surpasses $3 Million in Free Prescriptions
2. Poll: Hypothetical anthrax attack and antibiotics
3. Chitosan as alternative to growth-promoting antibiotics for ruminants
4. Hard to Treat Diseases (HTDS) Awarded Two Antibiotics Certificates For Chile
5. ID physicians call for 10 new antibiotics by 2020
6. Misinformation About Antibiotics Can Travel to Large Audience Via Twitter: Study
7. Misinformation about antibiotics can travel to large audience via Twitter: study
8. Combination antibiotics effective against chlamydia-induced arthritis
9. Quick Use of Antibiotics Best for COPD Flare-Ups
10. FDA Urges Limiting Antibiotics in Meat
11. Drug coverage under Medicare leads to increased use of antibiotics
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antibiotics Linked to Retinal Detachment Risk
(Date:6/27/2016)... NY (PRWEB) , ... June 27, 2016 , ... ... using cutting edge technology to revolutionize the emergency ambulance transport experience for the ... are aware of how Uber has disrupted the taxi industry through the use ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements ... that was developed to enhance the health of felines. The formula is all-natural and ... main herbs in the PawPaws Cat Kidney Support Supplement Soft Chews are ...
(Date:6/25/2016)... Miami, FL (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton ... Plant City Observer , brings up a new, often overlooked aspect of head lice: ... The closing for fumigation is not a common occurrence, but a necessary one in the ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, ... Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments in ... the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Marcy was in a crisis. Her son James, ... out at his family verbally and physically. , “When something upset him, he couldn’t control ... use it. He would throw rocks at my other children and say he was going ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)...  Arkis BioSciences, a leading innovator in the ... cerebrospinal fluid treatments, today announced it has secured ... led by Innova Memphis, followed by Angel Capital ... Arkis, new financing will accelerate the commercialization of ... of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... , June 23, 2016 ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, ... Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast to ... The global pharmaceutical excipients market ... at a CAGR of 6.1% in the forecast period ...
(Date:6/23/2016)... 23, 2016 Capricor Therapeutics, ... a biotechnology company focused on the discovery, development ... patient enrollment in its ongoing randomized HOPE-Duchenne clinical ... 50% of its 24-patient target. Capricor expects the ... quarter of 2016, and to report top line ...
Breaking Medicine Technology: