Navigation Links
Antibiotics Largest Cause of Drug-Induced Liver Damage
Date:12/1/2008

Prescription meds, supplements can also trigger acute organ failure, study says

MONDAY, Dec. 1 (HealthDay News) -- Antibiotics are the single largest class of drugs that cause idiosyncratic drug-induced liver injury (DILI), researchers say.

The condition accounts for about 13 percent of cases of acute liver failure in the United States and is the most common cause of death from acute liver failure.

DILI is caused by a wide range of prescription and nonprescription medications, nutritional supplements and herbal products. In a new study, Indiana University School of Medicine researchers looked at patients with suspected DILI and found that 73 percent of cases were caused by a single prescription medication, 9 percent by dietary supplements, and 18 percent by multiple agents. Patients with acetaminophen-related liver damage weren't included in the study.

Lead author Dr. Naga P. Chalasani and colleagues found that more than 100 different agents were associated with DILI and that antibiotics (45.5 percent) and nervous system agents (15 percent) were the most common. Among dietary supplements associated with DILI, those that claim to promote weight loss and muscle building accounted for almost 60 percent of cases. At least 20 percent of DILI patients ingested more than one potentially liver-damaging agent.

There was no association between patient gender and severity of DILI, but patients with diabetes had more severe DILI.

The study was published in the journal Gastroenterology.

"DILI is a serious health problem that impacts patients, physicians, government regulators and the pharmaceutical industry. Further efforts are needed in defining its pathogenesis and developing means for the early detection, accurate diagnosis, prevention and treatment," Chalasani said in an American Gastroenterological Association news release.

The researchers noted that DILI remains a diagnosis o
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Long-term antibiotics reduce COPD exacerbations, raise questions
2. Antibiotics can cause pervasive, persistant changes to microbiota in human gut
3. Researchers find new chemical key that could unlock hundreds of new antibiotics
4. Scientists Hot on Trail of New Antibiotics
5. Antibiotics May Not Cause Diarrheal Bacteria
6. Wheezing after early-life antibiotics
7. Physicians ask EPA, Antibiotics to cure sick apples, or sick children?
8. Averting postsurgical infections in kids: Give antibiotics within hour before first incision
9. LegalView Reveals Details of the FDA Mandated Black Box Warning For Fluoroquinolone Antibiotics Such as Cipro and Levaquin
10. FDA Mandates Black Box Warning for Some Antibiotics
11. Federal Action Needed to Fill Antibiotic Pipeline, Says the Alliance for the Prudent Use of Antibiotics
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antibiotics Largest Cause of Drug-Induced Liver Damage
(Date:2/26/2015)... 2015 The COR HEALTH division of ... Rhinebeck, NY, to offer customers a full line of ... that safely and effectively address muscle, joint, and nerve ... Vets Access LLC, Montrose, MI, that is dedicated to ... Topical BioMedics is a research and development leader in ...
(Date:2/26/2015)... Plains, NJ (PRWEB) February 26, 2015 ... the reopening of their newly renovated office in Lawrenceville, ... the Reproductive Science Center of New Jersey’s physicians, and ... work and patient care in the areas of infertility ... commended for having excellent success rates and providing current, ...
(Date:2/26/2015)... Beckman Coulter is sponsoring a new ... cargo in cell-to-cell communication,” which will focus on the ... communication. The webinar is free to attend and will ... , Every cell in the body can release several ... “exosomes” or “microvesicles.” These vesicles carry a wide array ...
(Date:2/26/2015)... Fort Lauderdale, FL (PRWEB) February 26, 2015 ... services is celebrating ten years of delivering high quality ... DC Metro, Florida and other regions across the United States. ... 2015 to be a pivotal year as it sets its ... massage and corporate office chair massage services. , “We’ve come ...
(Date:2/26/2015)... (PRWEB) February 26, 2015 Growth ... as evidenced by a EuroMonitor International Report that ... in 2018. In response to the robust ... campus is launching a barbering program in partnership ... Diego’s “The Factory” salon. The proprietary curriculum features ...
Breaking Medicine News(10 mins):Health News:COR HEALTH Division of Vets Access Partners with Topical BioMedics to Provide Natural Pain Relief Products 2Health News:COR HEALTH Division of Vets Access Partners with Topical BioMedics to Provide Natural Pain Relief Products 3Health News:RSCNJ Is Celebrating the Reopening of Their Newly Renovated Office 2Health News:RSCNJ Is Celebrating the Reopening of Their Newly Renovated Office 3Health News:Beckman Coulter Webinar Series Presents Diversity of Extracellular Vesicles and Their Cargo in Cell-to-cell Communication 2Health News:Beckman Coulter Webinar Series Presents Diversity of Extracellular Vesicles and Their Cargo in Cell-to-cell Communication 3Health News:Body Well Therapy Celebrates 10 Years of Quality Mobile Massage Services 2Health News:Body Well Therapy Celebrates 10 Years of Quality Mobile Massage Services 3Health News:Bellus Academy Partners with Renowned Hairstylist D.J. Muldoon to Launch Signature Barbering Program 2
... of Shamir, KIBBUTZ SHAMIR, Israel, July 1 ... leading provider of innovative,products and technology to the lens ... June 30, 2008, pursuant to which it has,purchased 49% ... to this transaction, Shamir held 51% of the share,capital ...
... Brooks forms alliance with Home Care Advantage, ... Home Care Advantage, a Jacksonville-based home,health care agency ... market and,more than $10 million in revenue. Home ... health agency in Jacksonville. Brooks, the largest,rehabilitation provider ...
... Corporation,(Nasdaq: RGEN ) announced today that Dr. Alfred ... Directors. Dr. Goldberg is currently a Professor of,Cell Biology ... noted in,particular for elucidating the structure and function of ... are destroyed in,cells. In addition, he has made major ...
... as a college course project to design therapeutic toys ... designed as therapy for children with cerebral palsy (CP). ... development of the brain and the motor system, often ... have been shown to be effective treatments in improving ...
... survey finds , , TUESDAY, July 1 (HealthDay News) -- ... of tobacco and alcohol use and the highest percentage of ... in their lives, a new survey shows. , Researchers from ... use in 17 countries in the Americas, Europe, Asia, the ...
... Teacher, Student Programs Focus on Sustainability, Diversity, ... diversity/workforce development in STEM (science, technology,engineering and mathematics) ... teachers and students that the Bayer USA Foundation ... United States., The two programs -- Green ...
Cached Medicine News:Health News:Shamir Optical Industry Purchases Remaining 49% of Altra Trading GmbH 2Health News:Shamir Optical Industry Purchases Remaining 49% of Altra Trading GmbH 3Health News:Jacksonville's Largest Rehab Provider Acquires Largest Home Health Agency 2Health News:Repligen Elects Alfred L. Goldberg, Ph.D. to the Board of Directors 2Health News:Repligen Elects Alfred L. Goldberg, Ph.D. to the Board of Directors 3Health News:Toys and technology for rehabilitation in cerebral palsy patients 2Health News:Toys and technology for rehabilitation in cerebral palsy patients 3Health News:Drug Use Increasingly Common in All Countries 2Health News:Bayer USA Foundation Supports Summer Science Education Programs in Pittsburgh, Raleigh, Houston and Tyler, Texas 2Health News:Bayer USA Foundation Supports Summer Science Education Programs in Pittsburgh, Raleigh, Houston and Tyler, Texas 3Health News:Bayer USA Foundation Supports Summer Science Education Programs in Pittsburgh, Raleigh, Houston and Tyler, Texas 4Health News:Bayer USA Foundation Supports Summer Science Education Programs in Pittsburgh, Raleigh, Houston and Tyler, Texas 5
(Date:2/26/2015)... 2015 The report, "Bottled ... Filler, Capper, Blow molder, Shrink wrapper), Technology (RO, ... Sparkling) & Region - Trends & Forecasts to ... bottled water processing market with analyses and projection ... value. It also identifies the driving and restraining ...
(Date:2/26/2015)... NEW YORK , Feb. 26, 2015 /PRNewswire/ ... Latin America is estimated at ... publisher said that population growth, government insurance, newly ... growth in the region and will continue to ... finding on torresearch into the market and interviews ...
(Date:2/26/2015)... , Feb. 26, 2015  CSSi, ( ... for the clinical research industry, is pleased to ... as a Project Manager, adding significant value ... Photo - http://photos.prnewswire.com/prnh/20150225/177750 ... a demonstrated ability to successfully lead the navigation ...
Breaking Medicine Technology:Bottled Water Processing Market Worth $2,106.5 Million by 2019 2Bottled Water Processing Market Worth $2,106.5 Million by 2019 3Bottled Water Processing Market Worth $2,106.5 Million by 2019 4Kalorama: Led by Brazil, IVD Test Market in Latin America Exceeds 2 Billion 2Kalorama: Led by Brazil, IVD Test Market in Latin America Exceeds 2 Billion 3Kalorama: Led by Brazil, IVD Test Market in Latin America Exceeds 2 Billion 4CSSi's Continued Growth Brings Talented New Hire - Karen Welch Welcomed as Project Manager 2
... NANJING, China, Jan. 13, 2011 /PRNewswire-Asia/ -- Simcere ... SCR ), a leading pharmaceutical company specializing ... and proprietary pharmaceuticals in China, today announced the ... for personal reasons, effective January 15, 2011. Simcere,s ...
... the third largest medical transcription service, speech recognition technology and ... has received the Best in KLAS Award for Transcription ... KLAS Awards: Software & Professional Services report. In addition ... was also rated No. 1 in their category for professional ...
Cached Medicine Technology:Simcere Pharmaceutical Group Announces Resignation of CFO Frank Zhao 2Webmedx Named Best in KLAS and Ranked #1 Transcription Services Vendor for Second Year in a Row 2Webmedx Named Best in KLAS and Ranked #1 Transcription Services Vendor for Second Year in a Row 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: