Navigation Links
Antibiotics Don't Help Most Sinus Infections, Study Finds
Date:2/14/2012

By Serena Gordon
HealthDay Reporter

TUESDAY, Feb. 14 (HealthDay News) -- Treating a sinus infection with antibiotics doesn't speed recovery, new research shows.

"We did a randomized clinical trial among adults with a clinical diagnosis of acute sinusitis, and found no benefit from the antibiotic compared to the placebo for the treatment of acute sinusitis," said study author Dr. Jane Garbutt, a research associate professor of medicine and pediatrics at Washington University School of Medicine in St. Louis.

Still, one in five antibiotic prescriptions for adults in the United States are written for sinus infections, according to the study.

"Acute sinusitis is a miserable disease. People want something to make them feel better, and there are not very many treatment options, so patients ask their doctors for antibiotics. But, we think most of the time, acute sinusitis is a viral infection, so antibiotics won't help," said Garbutt.

Results of the study are published in the Feb. 15 issue of the Journal of the American Medical Association.

Sinusitis is an inflammation of the sinus cavities. Pain in the forehead is a common symptom, according to the National Institute of Allergy and Infectious Diseases (NIAID). Another common symptom of sinusitis is nasal secretions, which may drip down the back of the throat, according to NIAID. Colds and allergies are common causes of sinusitis, though sometimes bacteria are at fault.

Current guidelines from the U.S. Centers for Disease Control and Prevention recommend antibiotics only for those with moderately severe or severe symptoms.

Given the increase of bacteria resistance to antibiotics, the researchers wanted to test their effectiveness, so they looked at 166 adults diagnosed with acute sinusitis. Thirty-six percent of the study volunteers were male and 78 percent were white, according to the study. People with chronic sinusitis (lasting more than 28 days) weren't included, as they may need a different treatment, the authors noted.

Study participants were randomly assigned to receive 10 days' treatment with either 1,500 milligrams of amoxicillin (an antibiotic) spread out over three doses daily or a placebo. All of the volunteers were also given treatments for pain, fever, cough and nasal congestion, and told to use them as needed.

Symptoms and other measures of quality of life were measured in phone interviews at three, seven, 10 and 28 days after starting treatment.

At day three, there was no difference in the symptoms between groups. At day seven, there was a small improvement in the antibiotic group, but Garbutt said the change was likely too small for a patient to even notice a difference in symptoms. At 10 days, there was again no difference in symptoms between the two groups.

By day 10, about 80 percent of those in both groups reported that their symptoms were much improved or cured. At day 28, there was no difference in relapse rates, the researchers said.

Garbutt said there were no statistically significant differences between the groups for other measures, such as the need for medications to relieve symptoms or days of missed work.

"Most people will get better from acute sinusitis on their own, but many people feel if they're not getting an antibiotic, nothing is being done," said Dr. Richard Lebowitz, an otolaryngologist at New York University Langone Medical Center in New York City.

He said there are things people can do on their own that may help them feel better faster. Saline irrigation of the sinuses can help, he said, as can decongestant or mucous-thinning medications that are sold over-the-counter.

"The average viral upper respiratory infection lasts one to two weeks, and treatment of symptoms is probably the appropriate treatment up to that point," he said. But, if your infection lasts longer than a week or two, or your symptoms suddenly get significantly worse, you should see your doctor.

"Some people do have bacterial infections, and they can be hard to identify," said Garbutt, who also recommended following up with your doctor if your symptoms don't improve or they suddenly get worse.

More information

Learn more about sinusitis from the U.S. National Institute of Allergy and Infectious Diseases.

SOURCES: Jane Garbutt, M.B., Ch.B., research associate professor, department of internal medicine, Washington University School of Medicine, St. Louis; Richard Lebowitz, M.D., otolaryngologist, New York University Langone Medical Center, and associate professor, NYU School of Medicine, New York City; Feb. 15, 2012 Journal of the American Medical Association


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. FDA Curbs Use of Certain Antibiotics in Livestock, Poultry
2. Antibiotics in Pregnancy May Shield Newborns From Strep B
3. More Sore Throats Seen in Acne Patients Taking Antibiotics
4. Preserving lifesaving antibiotics today and for the future
5. Southeast U.S. Still Using High Levels of Antibiotics, Study Shows
6. New method to diagnose sinusitis could reduce use of antibiotics
7. Community storage of anthrax-preventing antibiotics should be determined by state
8. Eye Antibiotics Can Cause Drug-Resistant Bacteria: Study
9. Antibiotics Beat Cranberries at Fighting Urinary Tract Infections in Study
10. Gonorrheas Growing Resistance to Antibiotics Concerns CDC
11. Van Andel Research Institute finding could lead to reduced side effects in anti-cancer antibiotics
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antibiotics Don't Help Most Sinus Infections, Study Finds
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of Family Medicine's (ABFM) Board ... Chief Executive Officer, succeeding Dr. James C. Puffer upon his retirement. Dr. Newton will ... Dr. Puffer’s retirement at the end of 2018. Upon assuming the role of President ...
(Date:10/13/2017)... ... 2017 , ... PurhealthRX , a leading Health and Nutrition Company, is ... to full spectrum CBD oil will revolutionize the rapidly growing CBD market by reducing ... easily incorporated into liquid products, while reducing costs to end users. , The team ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Lori R. Somekh, ... member of ElderCounsel, a national organization of elder law and special needs planning attorneys. ... and rules. It also provides a forum to network with elder law attorneys nationwide,” ...
(Date:10/13/2017)... ... 13, 2017 , ... Many families have long-term insurance that covers care for ... a waiver for care if the client has a cognitive impairment diagnosis. , ... care, is often waived, so the benefits from their insurance start immediately,” said Mechell ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading ... to advocate for action towards gender equality at their inaugural Summit in New York ... globe, and reached a social audience of over 3 million. To watch the Mobilize ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... Oct. 12, 2017   Divoti USA will ... to the standard of the latest FDA requirements, which stipulates new ... Anyone in need of Medical ID jewelry such as Medical ... are engraved in terms of the new FDA requirements ... Divoti offers this dark ...
(Date:10/11/2017)... Oct. 11, 2017  Caris Life Sciences ® , ... the promise of precision medicine, today announced that St. ... Precision Oncology Alliance™ (POA) as its 17 th ... St. Jude Crosson Cancer Institute will help develop standards ... of tumor profiling, making cancer treatment more precise and ...
(Date:10/10/2017)... , Oct. 10, 2017  NDS received FDA 510(k) clearance in ... medical-grade battery-powered display stand specifically designed for endoscopy environments. An innovative ... into a clinical solution to support the improvement of patient outcomes, ... Design ... Solution ...
Breaking Medicine Technology: