Navigation Links
Antibiotic regimen effective for reactive arthritis
Date:4/28/2010

lead to the demise of the infected cell. Dr. Carter explains why this is important. "Combining this effect with antibiotics that block chlamydial protein synthesis (e.g., doxycycline or azithromycin) may allow for successful eradication of the cell harboring persistently infecting intracellular organisms. A recent pilot study conducted by our group suggested that prolonged treatment with a combination of doxycycline and rifampin significantly improves symptoms of chronic undifferentiated spondylarthritis (SpA) (with a special focus on Chlamydia) compared with doxycycline alone. The goal of the present study was to further investigate whether a 6-month course of combination antibiotics, one of which is rifampin, is effective in the treatment of patients with chronic Chlamydia-induced ReA."

The 9-month, prospective, double-blind, triple-placebo trial screened a total of 80 subjects, and 42 were enrolled and randomized to treatment. Twelve subjects were randomized to doxycycline and rifampin, 15 were randomized to azithromycin and rifampin, and 15 were randomized to matching oral placebos. The primary end pointan improvement of 20% or morewas achieved in 17 of 27 patients (63%) receiving combination antibiotics and in 3 of 15 patients (20%) receiving placebo. Secondary efficacy end points showed similar results, demonstrating that compared with placebo, a 6-month course of combination antibiotics resulted in a significantly higher response rate in patients with chronic Chlamydia-induced ReA, although which combination of antibiotics was most effective remained undetermined as the trial wasn't powered to compare the 2 regimens.

Dr. Carter concludes, "The results of this study are encouraging for the management of chronic post-Chlamydia ReA. These data suggest that there is potential for eradication of this persistent infection and that improvement in the clinical sequelae that are the result of these infections can be achieved in a substantial number o
'/>"/>

Contact: Dawn Peters
medicalnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Reportlinker Adds Antibiotic Resistance and Antibiotic Technologies: Global Markets
2. Soil studies reveal rise in antibiotic resistance
3. Disinfectant Misuse Might Help Germs Resist Antibiotics
4. Giant Eagle Pharmacy Free Antibiotics Program Surpasses $3 Million in Free Prescriptions
5. Poll: Hypothetical anthrax attack and antibiotics
6. Chitosan as alternative to growth-promoting antibiotics for ruminants
7. Penicillin Allergy Might Not Include Related Antibiotic
8. Hard to Treat Diseases (HTDS) Awarded Two Antibiotics Certificates For Chile
9. ID physicians call for 10 new antibiotics by 2020
10. Misinformation About Antibiotics Can Travel to Large Audience Via Twitter: Study
11. Misinformation about antibiotics can travel to large audience via Twitter: study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... 22, 2015 Steven Winter Associates (SWA) ... has been selected by Consulting-Specifying Engineer (CSE) magazine as ... are featured in the May/June issue of the publication. ... professionals age 40 and younger who have, and continue ... well as in other areas of their professional and ...
(Date:5/22/2015)... Anaheim, Calif. (PRWEB) May 22, 2015 ... newly opened Anaheim Fit Body Boot Camp, recently accepted ... milestone so quickly after the launch of his location ... upon the Anaheim community. , Fit Body Boot Camp ... fitness boot camp franchise with hundreds of locations across ...
(Date:5/22/2015)... WI (PRWEB) May 22, 2015 ... honor to be recognized for providing the highest quality ... foundation of health care decision-making,” said Javon R. Bea, ... demonstrates the commitment of our employee/partners to care for ... patients.” , Hospitals do not apply for this award, ...
(Date:5/21/2015)... 21, 2015 Her popular Love Seminar will ... Hotel in San Gabriel on Saturday, May 23rd. , ... from men and women who are unhappy in their relationships ... , "Many singles think that their biggest problem is not ... go from one relationship to another trying to find the ...
(Date:5/21/2015)... Nashville, TN (PRWEB) May 21, 2015 Ticket Down ... soccer match featuring USA vs. Guatemala on Friday, July ... time is now to become a fan of international soccer. The ... the world play on American soil is growing at a large ... worldwide teams have come to the USA to play in front ...
Breaking Medicine News(10 mins):Health News:Steven Winter Associates’ Marc Zuluaga Earns Innovative Engineering Award 2Health News:Healthy Living Brought to Anaheim— New Fitness Boot Camp Acquires 100 Clients 2Health News:Mercy Hospital and Trauma Center Receives Women’s Choice Award for Emergency Care - Mercy Health System Javon Bea 2Health News:Bestselling Author Sheds Light on Why Modern Dating is Hurting People's Chances of Finding a Lasting Relationship 2Health News:USA vs. Guatemala Tickets: Ticket Down Slashes United States Men's Soccer Team (USMNT) vs. Guatemala Tickets at LP Field in Nashville on 7/3/15 2
... not prevent future aggressive gastric lymphoma since resting B ... led by Dr. Anne Mueller at Stanford University // ... al., "The role of antigenic drive and tumor-infiltrating accessory ... in the September issue of The American Journal of ...
... research report, by researchers from National Institute of Child Health ... suggest that a drug used for reducing the risk of ... an alternative to conducting surgery after a miscarriage., ,The ... of Medicine. , ,The drug, misoprostol, has been used ...
... A recent study has focused on the communication processes between ... of damaged cells, leading to blindness. , ,Normally cells ... cell to the other, enabling communication. For cells that don't ... which enables movement of molecules to and fro in the ...
... Researchers from HHS’ Agency for Healthcare Research and Quality ... may have been overrated, as the reported health benefits ... of soy protein found in tofu // and other ... low-density lipoprotein (LDL, known as bad cholesterol) and triglyceride ...
... adults. TB is a lung disease, caused by a ... with TB somewhere in the world every second. //, ... available which, however, fails to protect against the most ... multi-drug-resistant tuberculosis strains are on the rise, which cannot ...
... attuned to the care of his patients that he loses ... himself while doing so. A recent study has reported poor ... UK, supporting the above-mentioned statement. , ,Over 800 consultants ... was found among the respondents who belonged to gastroenterology, radiology, ...
Cached Medicine News:Health News:Helicobacter pylori Antibiotic Treatment of Peptic Ulcer May not Prevent Gastric lymphomas 2Health News:Drugs As Alternative To Surgery After Miscarriage 2Health News:Soy Benefits May Not Be As Much As Thought Before 2
(Date:5/21/2015)... CHICAGO , May 21, 2015 /PRNewswire-USNewswire/ ... lump along the side of his neck, ... and took a couple weeks off from ... didn,t go away.                               ... Rendino, 26, was referred to Michel ...
(Date:5/21/2015)... May 21, 2015 ... announced the addition of the "Arthroscopy ... offering. ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ,The purpose ... size the world market for Arthroscopy Devices. ... trends impacting the market for these products. ...
(Date:5/21/2015)... ANDOVER, Mass. , May 21, 2015 /PRNewswire/ ... into the Electronic Health Record (EHR) is invaluable ... ICU. Though EHRs are now a requirement and ... to and continuously into the EHR is gaining ... Software Exchange), William Holmes, RN, Site Project Manager ...
Breaking Medicine Technology:Northwestern Medicine Surgeons Develop New Approach to Removing Nerve Tumors 2Northwestern Medicine Surgeons Develop New Approach to Removing Nerve Tumors 3Northwestern Medicine Surgeons Develop New Approach to Removing Nerve Tumors 4Analysing Arthroscopy Devices Markets Worldwide 2014-2020 2Analysing Arthroscopy Devices Markets Worldwide 2014-2020 3Hospital Streamlines ICU Efficiency with Timely Data Integration 2Hospital Streamlines ICU Efficiency with Timely Data Integration 3
... Raptor Pharmaceutical Corp. (Nasdaq: RPTP ), today announced ... Company,s orally administered non-opioid, AMPA/kainate antagonist, will be presented ... Treatment of Neuropathic Pain, to be held November 20-21, ... ) , Mark Wallace, M.D., Professor of ...
... Varian, Inc. (NasdaqGS: VARI) today reported fourth quarter fiscal ... from the fourth quarter of fiscal year 2008. Orders ... of fiscal year 2009. , Non-GAAP (adjusted) diluted earnings per ... decrease of 48.7% from the $0.78 in the fourth quarter ...
Cached Medicine Technology:Raptor Pharmaceutical Corporation Announces Presentation of Data for NGX426, a Novel, Non-Opioid Oral Analgesic, at Neuropathic Pain Conference 2Raptor Pharmaceutical Corporation Announces Presentation of Data for NGX426, a Novel, Non-Opioid Oral Analgesic, at Neuropathic Pain Conference 3Raptor Pharmaceutical Corporation Announces Presentation of Data for NGX426, a Novel, Non-Opioid Oral Analgesic, at Neuropathic Pain Conference 4Raptor Pharmaceutical Corporation Announces Presentation of Data for NGX426, a Novel, Non-Opioid Oral Analgesic, at Neuropathic Pain Conference 5Varian, Inc. Reports Fourth Quarter 2009 Results 2Varian, Inc. Reports Fourth Quarter 2009 Results 3Varian, Inc. Reports Fourth Quarter 2009 Results 4Varian, Inc. Reports Fourth Quarter 2009 Results 5Varian, Inc. Reports Fourth Quarter 2009 Results 6Varian, Inc. Reports Fourth Quarter 2009 Results 7Varian, Inc. Reports Fourth Quarter 2009 Results 8Varian, Inc. Reports Fourth Quarter 2009 Results 9Varian, Inc. Reports Fourth Quarter 2009 Results 10Varian, Inc. Reports Fourth Quarter 2009 Results 11Varian, Inc. Reports Fourth Quarter 2009 Results 12Varian, Inc. Reports Fourth Quarter 2009 Results 13Varian, Inc. Reports Fourth Quarter 2009 Results 14Varian, Inc. Reports Fourth Quarter 2009 Results 15Varian, Inc. Reports Fourth Quarter 2009 Results 16Varian, Inc. Reports Fourth Quarter 2009 Results 17Varian, Inc. Reports Fourth Quarter 2009 Results 18Varian, Inc. Reports Fourth Quarter 2009 Results 19Varian, Inc. Reports Fourth Quarter 2009 Results 20Varian, Inc. Reports Fourth Quarter 2009 Results 21Varian, Inc. Reports Fourth Quarter 2009 Results 22
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: