Navigation Links
Antibiotic Linked to Heart Problems in COPD Patients
Date:3/22/2013

FRIDAY, March 22 (HealthDay News) -- A widely used antibiotic may increase the risk of heart problems in patients with lung conditions, according to a new study.

The antibiotic clarithromycin is commonly used to treat lower respiratory infections such as pneumonia and sudden worsening of chronic obstructive pulmonary disease (COPD). Previous research has suggested that the use of clarithromycin may increase the risk of heart problems such as heart failure, heart rhythm disorders and sudden cardiac death.

In this study, British researchers looked at data from about 1,300 patients with sudden worsening of COPD and about 1,600 patients with pneumonia. They found that 26 percent of the COPD patients who received clarithromycin experienced at least one heart problem over the next year, compared with 18 percent of those who were not given the antibiotic.

Twelve percent of pneumonia patients who received clarithromycin experienced at least one heart problem during the next year, compared with 7 percent of those who were not given the antibiotic, according to the study by James Chalmers of the University of Dundee, in Scotland, and colleagues.

The findings were published online March 21 in the journal BMJ.

In COPD patients, there was a significant association between the use of clarithromycin and death from heart-related problems. This association was not seen in pneumonia patients, according to a journal news release.

The longer patients with COPD or pneumonia used clarithromycin, the greater their risk of more heart problems. This was not the case with other antibiotics, which suggests an effect specific to clarithromycin, according to the study authors.

Overall, their findings suggest that there would be one additional heart problem for every eight COPD patients and every 11 pneumonia patients who receive clarithromycin, compared to patients who are not given the antibiotic.

The results also suggest that the increased risk of heart problems may last after patients stop taking clarithromycin, possibly due to the effect that the antibiotic has on the inflammation process in patients with chronic lung conditions, the researchers said.

They said their findings need to be confirmed before any changes in the treatment of COPD and pneumonia patients are made. Although the study showed a link between the use of clarithromycin and possible heart problems, it did not establish a cause-and-effect relationship.

More information

The American Academy of Family Physicians has more about antibiotics.

-- Robert Preidt

SOURCE: BMJ, news release, March 21, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Black Children Less Likely to Get Antibiotics: Study
2. FDA Renews Heart-Risk Warning for Antibiotic
3. Nearly a third of antibiotic prescriptions for dialysis patients inappropriate
4. Antibiotic-resistant strain of E. coli increasing among older adults and residents of nursing homes
5. Antibiotic resistance has the potential to undermine modern health systems
6. Strains of antibiotic-resistant Staph bacteria show seasonal preference; Children at higher risk in summer
7. Resurrection of 3-billion-year-old antibiotic-resistance proteins
8. Scientists unveil secrets of important natural antibiotic
9. New Antibiotic May Treat Skin Infections in Shorter Time
10. Chinas Overuse of Antibiotics in Livestock May Threaten Human Health
11. Antibiotic Resistance Strikes $15 Billion Ornamental Fish Industry
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antibiotic Linked to Heart Problems in COPD Patients
(Date:8/23/2017)... ... August 23, 2017 , ... A new ... Orthopaedic Surgeons , points out that therapeutic modalities (physical therapy) is an important ... to the report, a wider scope of physical therapy options is showing promising ...
(Date:8/22/2017)... ... August 22, 2017 , ... The old adage ... as simple as eating healthy foods. But this well-known piece of nutrition advice ... or breaking apart carbohydrates—depends not only on properties of the food but also ...
(Date:8/22/2017)... ... August 22, 2017 , ... ... solutions, announced recently the availability of a new professional fee E/M leveling calculator ... their service to the healthcare industry. E/M coding is complex which supports the ...
(Date:8/22/2017)... ... August 22, 2017 , ... “Wilderness Voices”: a collection ... travel. “Wilderness Voices” is the creation of published author, Martha McKown, an ordained ... was inspired as a very young child when her older sisters studied High School ...
(Date:8/22/2017)... ... August 22, 2017 , ... ... the Founder and Managing Member for t4 Leadership Development & Consulting. He has ... his definition of “success”: physician leadership development, servant leadership, data driven process improvement, ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... Mostyn Law and Gulf Coast Regional Blood Center to host ... Mostyn Law family has had 3 members that needed ... Mostyn Law is partnering with Gulf Coast Regional Blood Center ... Blood supplies are running low. Gulf Coast Regional Blood Center,s ... August. That is why the blood center reached out to ...
(Date:8/15/2017)... Calif. , Aug. 15, 2017  AOTI Inc. announced today ... Oxygen Therapy Inc., has recently opened a New York City Office ... ever-increasing usage of its unique Topical Wound Oxygen (TWO 2 ) ... by the Accreditation Commission for Health Care (ACHC) under the company,s ... ...
(Date:8/8/2017)... Israel, Aug. 8, 2017  BioLineRx Ltd. (NASDAQ/TASE: BLRX), ... today reports its financial results for the second quarter ... during the second quarter 2017 and to date: ... clinical development programs for the Company,s lead project, BL-8040: ... pivotal study with BL-8040 as novel stem cell mobilization ...
Breaking Medicine Technology: