Navigation Links
Antibiotic Linked to Heart Problems in COPD Patients
Date:3/22/2013

FRIDAY, March 22 (HealthDay News) -- A widely used antibiotic may increase the risk of heart problems in patients with lung conditions, according to a new study.

The antibiotic clarithromycin is commonly used to treat lower respiratory infections such as pneumonia and sudden worsening of chronic obstructive pulmonary disease (COPD). Previous research has suggested that the use of clarithromycin may increase the risk of heart problems such as heart failure, heart rhythm disorders and sudden cardiac death.

In this study, British researchers looked at data from about 1,300 patients with sudden worsening of COPD and about 1,600 patients with pneumonia. They found that 26 percent of the COPD patients who received clarithromycin experienced at least one heart problem over the next year, compared with 18 percent of those who were not given the antibiotic.

Twelve percent of pneumonia patients who received clarithromycin experienced at least one heart problem during the next year, compared with 7 percent of those who were not given the antibiotic, according to the study by James Chalmers of the University of Dundee, in Scotland, and colleagues.

The findings were published online March 21 in the journal BMJ.

In COPD patients, there was a significant association between the use of clarithromycin and death from heart-related problems. This association was not seen in pneumonia patients, according to a journal news release.

The longer patients with COPD or pneumonia used clarithromycin, the greater their risk of more heart problems. This was not the case with other antibiotics, which suggests an effect specific to clarithromycin, according to the study authors.

Overall, their findings suggest that there would be one additional heart problem for every eight COPD patients and every 11 pneumonia patients who receive clarithromycin, compared to patients who are not given the antibiotic.

The results also suggest that the increased risk of heart problems may last after patients stop taking clarithromycin, possibly due to the effect that the antibiotic has on the inflammation process in patients with chronic lung conditions, the researchers said.

They said their findings need to be confirmed before any changes in the treatment of COPD and pneumonia patients are made. Although the study showed a link between the use of clarithromycin and possible heart problems, it did not establish a cause-and-effect relationship.

More information

The American Academy of Family Physicians has more about antibiotics.

-- Robert Preidt

SOURCE: BMJ, news release, March 21, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Black Children Less Likely to Get Antibiotics: Study
2. FDA Renews Heart-Risk Warning for Antibiotic
3. Nearly a third of antibiotic prescriptions for dialysis patients inappropriate
4. Antibiotic-resistant strain of E. coli increasing among older adults and residents of nursing homes
5. Antibiotic resistance has the potential to undermine modern health systems
6. Strains of antibiotic-resistant Staph bacteria show seasonal preference; Children at higher risk in summer
7. Resurrection of 3-billion-year-old antibiotic-resistance proteins
8. Scientists unveil secrets of important natural antibiotic
9. New Antibiotic May Treat Skin Infections in Shorter Time
10. Chinas Overuse of Antibiotics in Livestock May Threaten Human Health
11. Antibiotic Resistance Strikes $15 Billion Ornamental Fish Industry
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antibiotic Linked to Heart Problems in COPD Patients
(Date:10/12/2017)... LA (PRWEB) , ... October 12, 2017 , ... Planet ... in the U.S., announced today its plans to open a flagship location in Covington, ... occupy the former Rooms To Go store next to Office Depot in the Holiday ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... The American ... Excellence to Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium ... 8. , In honor of Morris F. Collen, a pioneer in the field of ...
(Date:10/12/2017)... ... 2017 , ... Dr. Parsa Mohebi, the Los Angeles based ... the newly revamped Cosmetic Town journal section, featuring articles written by ... as Follicular Unit Extraction (FUE). , Dr. Mohebi says “I enjoy ...
(Date:10/12/2017)... ... October 12, 2017 , ... On Saturday, October 21, ... relay – Miles by Moonlight to raise money for the American Heart Association Heart ... , Teams will work together to keep their treadmills moving for 5 hours. ...
(Date:10/12/2017)... ... October 12, 2017 , ... In the United States, single-family ... some states—like New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and California—the average ... extremely low property-tax rates, which contributes to the relatively lower cost of living ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... 2017 West Pharmaceutical Services, Inc. ... injectable drug administration, today announced that it will release ... Thursday, October 26, 2017, and will follow with a ... at 9:00 a.m. Eastern Time. To participate on the ... conference ID is 94093362. ...
(Date:10/11/2017)... , Oct. 11, 2017  Caris Life Sciences ... on fulfilling the promise of precision medicine, today announced ... joined Caris, Precision Oncology Alliance™ (POA) as its 17 ... centers, the St. Jude Crosson Cancer Institute will help ... the use of tumor profiling, making cancer treatment more ...
(Date:10/11/2017)... 11, 2017  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), ... in Las Piedras, Puerto Rico , ... Following a ... sustained minor structural damage, temporary loss of power and ... been completed, manufacturing operations have resumed, and the company ...
Breaking Medicine Technology: