Navigation Links
Antibiotic Linked to Heart Problems in COPD Patients
Date:3/22/2013

FRIDAY, March 22 (HealthDay News) -- A widely used antibiotic may increase the risk of heart problems in patients with lung conditions, according to a new study.

The antibiotic clarithromycin is commonly used to treat lower respiratory infections such as pneumonia and sudden worsening of chronic obstructive pulmonary disease (COPD). Previous research has suggested that the use of clarithromycin may increase the risk of heart problems such as heart failure, heart rhythm disorders and sudden cardiac death.

In this study, British researchers looked at data from about 1,300 patients with sudden worsening of COPD and about 1,600 patients with pneumonia. They found that 26 percent of the COPD patients who received clarithromycin experienced at least one heart problem over the next year, compared with 18 percent of those who were not given the antibiotic.

Twelve percent of pneumonia patients who received clarithromycin experienced at least one heart problem during the next year, compared with 7 percent of those who were not given the antibiotic, according to the study by James Chalmers of the University of Dundee, in Scotland, and colleagues.

The findings were published online March 21 in the journal BMJ.

In COPD patients, there was a significant association between the use of clarithromycin and death from heart-related problems. This association was not seen in pneumonia patients, according to a journal news release.

The longer patients with COPD or pneumonia used clarithromycin, the greater their risk of more heart problems. This was not the case with other antibiotics, which suggests an effect specific to clarithromycin, according to the study authors.

Overall, their findings suggest that there would be one additional heart problem for every eight COPD patients and every 11 pneumonia patients who receive clarithromycin, compared to patients who are not given the antibiotic.

The results also suggest that the increased risk of heart problems may last after patients stop taking clarithromycin, possibly due to the effect that the antibiotic has on the inflammation process in patients with chronic lung conditions, the researchers said.

They said their findings need to be confirmed before any changes in the treatment of COPD and pneumonia patients are made. Although the study showed a link between the use of clarithromycin and possible heart problems, it did not establish a cause-and-effect relationship.

More information

The American Academy of Family Physicians has more about antibiotics.

-- Robert Preidt

SOURCE: BMJ, news release, March 21, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Black Children Less Likely to Get Antibiotics: Study
2. FDA Renews Heart-Risk Warning for Antibiotic
3. Nearly a third of antibiotic prescriptions for dialysis patients inappropriate
4. Antibiotic-resistant strain of E. coli increasing among older adults and residents of nursing homes
5. Antibiotic resistance has the potential to undermine modern health systems
6. Strains of antibiotic-resistant Staph bacteria show seasonal preference; Children at higher risk in summer
7. Resurrection of 3-billion-year-old antibiotic-resistance proteins
8. Scientists unveil secrets of important natural antibiotic
9. New Antibiotic May Treat Skin Infections in Shorter Time
10. Chinas Overuse of Antibiotics in Livestock May Threaten Human Health
11. Antibiotic Resistance Strikes $15 Billion Ornamental Fish Industry
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antibiotic Linked to Heart Problems in COPD Patients
(Date:6/25/2016)... , ... June 25, 2016 , ... ... policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at ... on several important health care topics including advance care planning, healthcare costs and ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room ... Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. ... of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of ...
(Date:6/25/2016)... ... 2016 , ... Conventional wisdom preaches the benefits of moderation, whether it’s a ... the bar too high can result in disappointment, perhaps even self-loathing. However, those who ... , Research from PsychTests.com reveals that behind the tendency to set ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA ... the Road To Recovery® program to drive cancer patients to and from their cancer ... ensure the highest quality of life and ongoing independence. Getting to and from ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Ill. , June 23, 2016  In a startling report ... are failing their residents by lacking a comprehensive, proven plan to ... a definitive ranking of how states are tackling the worst ... to only four states – Kentucky , ... Vermont . Of the 28 failing states, three ...
(Date:6/23/2016)... Research and Markets has announced the addition of ... Forecast to 2022" report to their offering. ... date financial data derived from varied research sources to present ... impact on the market during the next five years, including ... sub markets, regional and country level analysis. The report provides ...
(Date:6/23/2016)... 2016 Research and Markets has announced ... report to their offering. ... a favourable commercial environment for MedImmune to enter. The US ... will serve to drive considerable growth for effective anti-influenza medications. ... cap sales considerably, but development is still in its infancy. ...
Breaking Medicine Technology: