Navigation Links
Antibacterial chemical disrupts hormone activities
Date:12/7/2007

A new UC Davis study shows that a common antibacterial chemical added to bath soaps can alter hormonal activity in rats and in human cells in the laboratoryand does so by a previously unreported mechanism.

The findings come as an increasing number of studies of both lab animals and humans are revealing that some synthetic chemicals in household products can cause health problems by interfering with normal hormone action.

Called endocrine disruptors, or endocrine disrupting substances (EDS), such chemicals have been linked in animal studies to a variety of problems, including cancer, reproductive failure and developmental anomalies.

This is the first endocrine study to investigate the hormone effects of the antibacterial compound triclocarban (also known as TCC or 3,4,4'-trichlorocarbanilide), which is widely used in household and personal care products including bar soaps, body washes, cleansing lotions, wipes and detergents. Triclocarban-containing products have been marketed broadly in the United States and Europe for more than 45 years; an estimated 1 million pounds of triclocarban are imported annually for the U.S. market.

The researchers found two key effects: In human cells in the laboratory, triclocarban increased gene expression that is normally regulated by testosterone. And when male rats were fed triclocarban, testosterone-dependent organs such as the prostate gland grew abnormally large.

Also, the authors said their discovery that triclocarban increased hormone effects was new. All previous studies of endocrine disruptors had found that they generally act by blocking or decreasing hormone effects.

This finding may eventually lead to an explanation for some rises in some previously described reproductive problems that have been difficult to understand, said one author, Bill Lasley, a UC Davis expert on reproductive toxicology and professor emeritus of veterinary medicine. More analyses of antibacterials and endocrine effects are planned, he said.

Consumers should not take this study as guidance on whether to use triclocarban-containing products, Lasley said. Our mothers taught us to wash our hands well before the advent of antimicrobial soaps, and that practice alone prevents the spread of disease.


'/>"/>

Contact: Bill Lasley
bllasley@ucdavis.edu
415-669-7927
University of California - Davis
Source:Eurekalert

Related medicine news :

1. Antibacterial Soap Claims Just Dont Wash
2. Chemical culprit in popcorn workers lung identified
3. American Chemical Societys Weekly Presspac -- Sept. 5, 2007
4. Rohm and Haas to Webcast Presentation at Credit Suisse Chemicals Conference
5. Chemical Diversity Initiates International Prostrate Cancer Discovery Partnership
6. Low Doses of Red Wine Chemical May Fight Diabetes
7. National Academies advisory: genes and toxic chemicals
8. Genomic technologies to identify toxic chemicals should be developed
9. Malaria No More and Sumitomo Chemical Help Protect 1.4 Million Kids from Malaria
10. American Chemical Societys Weekly Presspac -- Oct. 17, 2007
11. Researchers study potential health benefits of natural chemicals in muscadine grape seeds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2016)... ... February 09, 2016 , ... IsoComforter, Inc., one of ... the newly designed, innovative shoulder wrap. The newly designed shoulder wrap has ... injured arm and shoulder to promote faster healing. It is highly recommended for ...
(Date:2/9/2016)... (PRWEB) , ... February 09, 2016 , ... ... grout cleaning and sealing company , is proud to announce that many of ... superior levels of customer service. The hard surface restoration franchises received customer recognition ...
(Date:2/9/2016)... Ashburn, VA (PRWEB) , ... February 09, 2016 ... ... ) Small Mammal Prize has officially been won. A team from 21st Century ... has discovered a way to preserve the delicate neural circuits of an intact ...
(Date:2/8/2016)... ... February 08, 2016 , ... ... Nutrition into the Food & Beverage and Dietary Supplement ... partner throughout Canada and USA geographies east of the Rocky Mountains since 2012. ...
(Date:2/8/2016)... ... 2016 , ... The Valentine’s Season is famous for gift giving with flowers, chocolates and other ... loved. This year, for more than 5.6 million Americans suffering with Alzheimer’s, those store ... to remind them of the lives they’ve led and the people they’ve touched. ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... Alzheimer Diagnostic Tests - Medical Devices Pipeline Assessment, ... report , "Alzheimer Diagnostic Tests - Medical Devices ... Diagnostic Tests currently in pipeline stage. The ... with comparative analysis of the products at various ... involved in the pipeline product development. It also ...
(Date:2/8/2016)... 2016 CBG Technologies, a U.S. company, ... Recycling Systems, specifically designed for precision parts cleaning. ... and existing vapor degreasers, parts washers and ultrasonic ... continuous recycling and recovers 100% of the solvent ... --> Precision parts manufacturers benefit from this ...
(Date:2/8/2016)... 2016 --> ... "Ablation Technologies Market by Product (Radiofrequency, Ultrasound, Irreversible Electroporation, ... Surgery, Ophthalmology, Gynecology) - Global Forecasts to 2020", published ... the forecast period of 2015 to 2020. The market ... CAGR of 10.5% from 2015 to 2020. ...
Breaking Medicine Technology: