Navigation Links
Anti-spasticity medications need further research
Date:1/27/2010

Only a few anti-spasticity medications used for children with cerebral palsy are backed by sufficient research to justify their use, according to a new review of scientific literature headed by a UT Southwestern Medical Center neurologist and conducted by a national panel of interdisciplinary experts nationwide.

The findings prompted the American Academy of Neurology to release a new practice guideline on effective treatments. Dr. Mauricio Delgado-Ayala, professor of neurology at UT Southwestern is lead author of the guideline, which appears in the Jan. 26 issue of the academy's journal, Neurology.

Botulinum toxin type A, sold under the brand names Botox and Dysport, is effective and generally safe to relieve spasticity, the researchers found. The drugs diazepam (Valium) and tizanidine (Zanaflex, Sirdalud) can also be used, although they carry more risks.

The researchers found insufficient evidence on whether other commonly used drugs are effective or safe.

A statement by the academy said that practice guidelines are intended to keep neurologists up to date on clinical research and improve medical treatment; they are not intended as hard-and-fast rules.

"The guideline identified a need for more research on most drugs used to treat generalized spasticity," said Dr. Delgado-Ayala. "These drugs might work and be safe, but that needs to be proved.

The lack of evidence does not mean that existing treatment methods are not effective and safe, but it should make us pause and realize that more research needs to be conducted."Most of the medications we use in children were originally studied in adults," Dr. Delgado-Ayala said. "We need to know more about how these medications work in the body, and the doses for best results and least side effects, not only to reduce spasticity but also to improve quality of life."

About 10,000 babies a year in the U.S. are born with cerebral palsy. Cerebral palsy comp
'/>"/>

Contact: Aline McKenzie
aline.mckenzie@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. A novel computational model -- how Parkinsons medications affect learning and attention
2. First Oral Medications For MS Show Promise
3. Monitoring of high-risk medications unchanged despite FDA warnings
4. Urinary Incontinence Rates Increase Worldwide As Awareness Grows About Treatment Options: Urethral Slings Are Popular Alternatives When Medications Fail
5. Pathological Gambling May Be Successfully Treated With Medications for Substance Addiction
6. Study highlights lack of patient knowledge regarding hospital medications
7. TheBody.com Launches My Health Tracker, Enabling HIV-Positive Patients to Track Lab Results, Medications and Supplements
8. Sinusitis Treatment Using Nebulized Medications to Treat Sinusitis Rather than Sinus Surgery
9. Greater certainty in monitoring 3 therapeutic medications is facilitated by new CRMs
10. Pelosi Applauds Provisions in Health Bill to Improve Access to Care, Medications for People Living With HIV/AIDS
11. Antipsychotic Medications Cause Substantial Weight Gain in Children and Adolescents, According to Scientists at the Feinstein Institute for Medical Research and Zucker Hillside Hospital
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... At the end of February 2015, Choices ... to the Oscars” in the Stardust Penthouse on the ... impressive Los Angeles skyline. These events honoring the 2015 ... leading producer of sustainable product placement in TV and ... providers of eco-friendly and socially conscious products and services, ...
(Date:4/17/2015)... 17, 2015 Testosterone treatment lawsuits ... of prescription medications increases the likelihood that a ... other life-threatening cardiovascular event continue to mount in ... Northern District of Illinois. According to an updated ... on Multidistrict Litigation (JPML) on April 15th, 1,382 ...
(Date:4/17/2015)... Organic Valley, the nation’s largest cooperative of ... Year of Soils by “Cycling for Sustainability” through California ... will travel 215 miles from Auburn, California, to the ... the impact of agriculture on water and soil in ... Wisconsin, Oregon, and Washington state, the cyclists have diverse ...
(Date:4/17/2015)... The American College of Traditional Chinese Medicine (ACTCM) is ... April 29. The event will be held from 11 a.m. to ... St. in San Francisco, CA. , The agenda for the day ... DeHaro campus (room F), 11:10 a.m. – Introduction and welcome ... lunch with current students, faculty and staff, 1 p.m. – Observe ...
(Date:4/17/2015)... NY (PRWEB) April 17, 2015 Calvary Hospital ... Fund, Inc. as Executive Vice President on May 11. The ... unique and historic mission. Barr succeeds Vincent J. Spinelli, who ... has agreed to take on and supervise the important work ... president and CEO. “As Calvary continues to expand and bring ...
Breaking Medicine News(10 mins):Health News:Choices Recovery Speaks with Dakota Hood of “The Hunger Games” about Addiction in Hollywood 2Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 2Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 3Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 4Health News:Organic Valley Farmers and Employees "Cycling for Sustainability" Through 215 Miles of California Watershed April 19-25 2Health News:Organic Valley Farmers and Employees "Cycling for Sustainability" Through 215 Miles of California Watershed April 19-25 3Health News:American College of Traditional Chinese Medicine Hosts Open House 2Health News:Timothy P. Barr Appointed Executive Vice President of Calvary Fund 2Health News:Timothy P. Barr Appointed Executive Vice President of Calvary Fund 3
... been homeless for any period of time after leaving ... accessing health care than those with stable housing situations, ... Archives of Pediatrics & Adolescent Medicine, one of the ... period of time after leaving the foster care system ...
... 1 More than 125 leaders,from throughout the ... joined,together to support a multi-year, statewide campaign to ... campaign, launched by Nemours Health,and Prevention Services (NHPS), ... health professionals, parents, and other leaders to,improve the ...
... the,Supreme Court,s refusal to hear a case defending a ... coverage, Judie Brown,president of American Life League, issued the ... fiat has reached new levels,today as the Supreme Court ... do not want to provide contraceptives as part,of the ...
... Oct. 1 Mylan Laboratories Inc.,(NYSE: MYL ) ... Vice,President and Treasurer, effective October 22, 2007. Mr. Byala ... with responsibility for,treasury planning in both New York and ... in various treasury positions of increasing responsibility.,Prior to Pfizer, ...
... LAWRENCE, Mass., Oct. 1 NxStage Medical, Inc.,(Nasdaq: ... System One(TM) portable,kidney dialysis machine, today announced that ... and certain affiliated entities,("Medisystems") for 6.5 million shares ... we now have the components in place to ...
... 1 A visionary leader, Dr.,Maria Cristina ... her outstanding contributions to the prevention and ... the 27th Pan American Sanitary Conference,proceedings today. ... Health is bestowed upon creative leaders whose ...
Cached Medicine News:Health News:Poor health care access common among youth leaving foster system 2Health News:Poor health care access common among youth leaving foster system 3Health News:More than 125 State Leaders - Including Governor, Lt. Governor, and Congressional Delegation - Endorse Campaign to Make Delaware's Kids the Healthiest in the Nation 2Health News:More than 125 State Leaders - Including Governor, Lt. Governor, and Congressional Delegation - Endorse Campaign to Make Delaware's Kids the Healthiest in the Nation 3Health News:Mylan Announces Appointment of Brian Byala as Senior Vice President and Treasurer 2Health News:NxStage Medical Completes Acquisition of Medisystems 2Health News:NxStage Medical Completes Acquisition of Medisystems 3Health News:Inter-American Leadership Award Bestowed Upon Chilean Chronic Disease Expert 2
(Date:4/17/2015)... April 17, 2015   IBA Molecular, a ... announced today that it has signed a definitive agreement ... Inc. (IBAM NA), to Illinois Health and Science (IHS). Under ... an independent company headquartered in Dulles, Virginia ... advantage of new product and footprint synergies. IBA Molecular ...
(Date:4/17/2015)... DUBLIN , Apr. 16, 2015 Research and ... addition of the "Corporate Reputation of Pharma in ... - 1st Edition" report to their offering. ... has compared opinions on the corporate reputation of the ... in mental health with the views of patient organisations ...
(Date:4/17/2015)... , April 17, 2015 Bionomics Limited ... and development of innovative therapeutics for the treatment of ... announced the presentation of data from three of its ... for Cancer Research (AACR) 106 th Annual Meeting ... Philadelphia, PA USA. The ...
Breaking Medicine Technology:Health Care System to Acquire IBA Molecular North America 2Health Care System to Acquire IBA Molecular North America 3Corporate Reputation of Pharma in 2014 - The Perspective of Mental Health Patient Groups - 1st Edition 2Corporate Reputation of Pharma in 2014 - The Perspective of Mental Health Patient Groups - 1st Edition 3Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 2Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 3Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 4Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 5
... , ST. LOUIS, Oct. 30 Stereotaxis received notice ... CE Mark for distribution in the European market. ... from the on-going co-development agreement between Stereotaxis and Biosense ... use in the Niobe Magnetic Navigation System (MNS). ...
... Inc. (NYSE: MTD ) today announced third quarter results for ... in local currency declined by 12% in the quarter. Reported ... , Net earnings per diluted share as reported (EPS) ... Adjusted EPS was $1.36, a 6% decline from the prior-year ...
Cached Medicine Technology:Stereotaxis Receives Notice of European Approval of an Additional Magnetic Irrigated Catheter 2Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 2Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 3Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 4Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 5Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 6Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 7Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 8Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 9Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 10Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 11Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 12Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 13
Solid 14 mm free-swinging blades, suture posts, and stabilizing disk. Dull finish....
Designed for use with foster enucleation snare (E3670). Package of 12 stainless steel wires. Overall length 5.3 inches....
Open ring design for globe fixation during various ocular procedures. Blunt fixation points. Swivel handle provides increased flexibility. Manufactured in titanium....
Adult size. Loops retract lids. Polished finish....
Medicine Products: