Navigation Links
Anti-epilepsy drug risk on cognitive function for unborn children
Date:7/21/2009

LIVERPOOL, UK 21 July 2009: Interim results of a study being conducted by scientists at the University of Liverpool suggest that children aged three years and younger, who are born to women taking the anti-epileptic drug sodium valproate whilst pregnant, are likely to have an IQ of six to nine points lower than average.

The research, in collaboration with Emory University in the US and the Central Manchester University Hospitals NHS Foundation Trust, tested more than 300 three-year-olds in the UK and US, whose mothers took one of four anti-epilepsy drugs (AEDs) whilst pregnant. The preliminary findings suggest that children exposed to the drug sodium valproate had lower IQ results than children exposed to other AEDs, regardless of the mother's IQ. The results also took dosage, duration of pregnancy and mother's consumption of folic acid whilst pregnant, into account.

Professor of Clinical Neuropsychology at the University, Gus Baker, said "Our research looked at how exposure to sodium valproate and other AEDs in the womb affected children's everyday life in particular their IQ, memory and language abilities from one to six years of age."

Around 5,000 women with epilepsy become pregnant every year in the UK and the majority of these, including those on AEDs, will experience uncomplicated pregnancies and births. Previous research conducted by the team has already shown that children exposed to AEDs such as sodium valproate in the womb are more likely to suffer birth defects characterised by heart malformations, dysmorphic features and minor limb deformities.

Professor Baker added: "The answer is not as simple as to take women off AEDs altogether as the effects of suffering a seizure can also pose a risk for both mother and unborn child. It is vital that the research is now used to educate women with epilepsy before they start to plan for a family. Women need to be aware of the risks so that they can make informed choices w
'/>"/>

Contact: Kate Spark
kate.spark@liv.ac.uk
44-151-794-2247
University of Liverpool
Source:Eurekalert

Page: 1 2

Related medicine news :

1. UCB Announces Positive Results From Phase II Clinical Trial of Investigational Anti-Epilepsy Drug Brivaracetam
2. Lack of sleep among new school-goers leads to behavioral, cognitive problems
3. Low level of neuronal receptor linked to mild cognitive impairment and Alzheimers disease
4. Cognitive Activities Protect Against Alzheimers -- Social and Physical Activities Not Enough
5. Potential new approach to treat cognitive impairments in schizophrenia
6. Cognitive deficits lead to loss of self among cancer patients
7. Research links diet to cognitive decline and dementia
8. First Cognitive Training to Demonstrate Immediate Generalizability Through Standardized Assessments of Memory
9. New research on aging and cognitive training presented at GSAs Annual Meeting
10. Hypertension Linked to Risk of Mild Cognitive Impairment
11. Rhode Island Hospital to study driving ability of cognitively impaired elders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... OR (PRWEB) November 26, 2014 The ... fresh water shortages, is moving forward with a plan ... drinking water.* Radio host Sharon Kleyne supports the San ... “Total Water Management” (TWM). According to Kleyne, by recycling ... constantly import new water could be greatly reduced. (Spagat, ...
(Date:11/26/2014)... Loffler Companies has been selected as ... an online information and news publication for resellers of ... consecutive year Loffler has earned this prestigious award and ... Dealer Awards honor the best and the brightest in ... honorees were chosen for their innovative marketing and sales ...
(Date:11/26/2014)... WOODLAND HILLS, CA (PRWEB) November 26, 2014 ... implants costing thousands of dollars, the prosthodontists at the Anacapa ... that paying for dental procedures can be daunting for some. ... to pay for the procedures they offer. , “No dentist ... functioning and beautiful set of teeth,” said Dr. Mamaly Reshad, ...
(Date:11/26/2014)... Senior Planning Services, providing “expert guidance for ... providing the adult demographic education and access to ... the rough seas of applying for Medicaid. Part of ... topic of Medicaid eligibility and proper planning, while also ... for this coverage. , Senior Planning Services has ...
(Date:11/26/2014)... ISI Telemanagement Solutions, Inc., a ... award the 2014 Lync Pioneer Award ... as a great honor to ISI, who continues ... Specifically, ISI offers an integrated collaboration reporting and ... including voice, video, Lync IM, and conferencing. ...
Breaking Medicine News(10 mins):Health News:Global fresh water advocate supports San Diego wastewater recycling plan 2Health News:Global fresh water advocate supports San Diego wastewater recycling plan 3Health News:Loffler Companies Recognized as an Elite Dealer for Sixth Consecutive Year 2Health News:Anacapa Dental Art Institute Doctors Offers 6 Tips on How to Pay for Cosmetic, Restorative and Implant Dentistry 2Health News:Anacapa Dental Art Institute Doctors Offers 6 Tips on How to Pay for Cosmetic, Restorative and Implant Dentistry 3Health News:Anacapa Dental Art Institute Doctors Offers 6 Tips on How to Pay for Cosmetic, Restorative and Implant Dentistry 4Health News:Anacapa Dental Art Institute Doctors Offers 6 Tips on How to Pay for Cosmetic, Restorative and Implant Dentistry 5Health News:Senior Planning Services Teams Up with SeniorNet To Educate Seniors On Medicaid Planning 2Health News:ISI Telemanagement Solutions, Inc. has been Awarded the 2014 Microsoft Lync Pioneer Award 2
... French and Spanish . , Researchers from ... belonging to the Laboratorio de Ciencias de la Visin y Aplicaciones, ... the tool required to implement it, which has been named "halometer". ... and a computer where the mouse is used as a response ...
... the old journalistic adage goes. Not necessarily, say researchers from ... of the Jewish General Hospital. In a first-of-its kind study ... versus 20 years ago, positivity and hope seem to be ... potential impact on patient perspectives," said Dr. Melissa Henry, the ...
... Epidemiology Unit, Southampton, UK, and Dr. Michal Hiligsmann ... with the ESCEO Young Investigator Awards, supported by a ... European Congress on Osteoporosis & Osteoarthritis (ECCEO11-IOF) now taking ... 2,500, recognize young investigators for their excellence in bone ...
... March 23, 2011 Although acupuncture is commonly used ... remain. Investigators from the Universities of Exeter & Plymouth ... (Daejeon, South Korea) critically evaluated systematic reviews of acupuncture ... this question. Reporting in the April 2011 issue of ...
... with Sichuan University in Chengdu, China, investigated eye movements in ... mechanisms that control them and how they compare between different ... movement, that is rare in British people, is much more ... differences in brain function between different populations. ...
... By Amanda Gardner HealthDay Reporter , ... developed a new way of predicting when breast cancer ... "epigenetic signatures" seem to distinguish more aggressive cancers from ... Epigenetic alterations do not involve changes to the ...
Cached Medicine News:Health News:Researchers develop a halometer that tests alterations in night vision 2Health News:Researchers develop a halometer that tests alterations in night vision 3Health News:Good news! Hope makes headlines 2Health News:Acupuncture for pain no better than placebo and not without harm 2Health News:Eye movement differs in British and Chinese populations 2Health News:Genes' 'On/Off' Switches Yield Clues to Breast Cancer 2Health News:Genes' 'On/Off' Switches Yield Clues to Breast Cancer 3
(Date:11/24/2014)...  Arena Pharmaceuticals, Inc. (NASDAQ: ARNA ) announced today ... and update at the Piper Jaffray 26 th Annual ... Eastern Time (5:30 a.m. Pacific Time), at The New York ... A live audio webcast of the presentation will be ... www.arenapharm.com . A replay of the presentation will be ...
(Date:11/24/2014)... , Nov. 24, 2014 /PRNewswire/ - Milestone Pharmaceuticals, ... trial conducted in Melbourne, Australia ... for the potential treatment of paroxysmal supraventricular tachycardia ... of MSP-2017 was well tolerated at single doses ... excellent safety profile, desirable PK properties including rapid ...
(Date:11/24/2014)... , Nov. 24, 2014  Marta Rendon, MD, founder ... Boca Raton , FL and international key opinion leader ... from the United States to attend ... Istanbul, Turkey . Here, at this gathering of ... as world renowned facial plastic surgery experts from ...
Breaking Medicine Technology:Arena Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 2Arena Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 3Milestone Announces Positive Phase 1 Data for MSP-2017; Supports Advancement into Phase 2 in PSVT Patients 2Milestone Announces Positive Phase 1 Data for MSP-2017; Supports Advancement into Phase 2 in PSVT Patients 3Marta Rendon, MD Selected To Attend Prestigious, Global Aesthetic Experts Summit! 2Marta Rendon, MD Selected To Attend Prestigious, Global Aesthetic Experts Summit! 3
... DIEGO, Nov. 18 Rules-Based Medicine, Inc. (RBM) today announced ... with Covance Inc. (NYSE: CVD ) that will ... biomarker technologies and services for use in drug development. Under ... exclusive third-party provider of multiplexed protein biomarker testing services, and ...
... , , TEMECULA, Calif., Nov. 17 ... announced third quarter 2009 results. , "We are continuing ... increases in our gross margins," stated Steven H. Kane, ... third quarter revenues from sales of safety sponges were ...
Cached Medicine Technology:Rules-Based Medicine Forms Biomarker Alliance With Covance Inc. 2Rules-Based Medicine Forms Biomarker Alliance With Covance Inc. 3Patient Safety Technologies Reports Third Quarter Results 2Patient Safety Technologies Reports Third Quarter Results 3Patient Safety Technologies Reports Third Quarter Results 4Patient Safety Technologies Reports Third Quarter Results 5Patient Safety Technologies Reports Third Quarter Results 6
... Our variable volume Finnpipette ... in a high performance pipette. ... colour-coded volume range, ensures quality, ... identification of the volume range ...
... Reference Series 2000 Pipette is a synonym ... compact and robust design, and superior operating ... to operate the measuring stroke and blow-out ... Product features: Eppendorf "pipette/tip" system ensures ...
Pipetman P is a fully adjustable, air-displacement pipette with the selected volume shown on a digital indicator (volumeter). Eight models cover the full range of volumes from 0.2 L to 10 mL....
... Intersurgical Incorporated manufactures high ... and moisture exchangers, ventilator ... hand-held nebulizers and an ... and connectors for anesthesia ...
Medicine Products: