Navigation Links
Anti-Rejection Drug May Boost Diabetes in Kidney Transplant Patients
Date:5/29/2008

Those treated with sirolimus faced up to 66% increased risk of disease after operation

THURSDAY, May 29 (HealthDay News) -- Treatment with the anti-rejection drug sirolimus may lead to increased risk of diabetes in kidney transplant patients, say researchers who analyzed data on about 20,000 Medicare patients who had kidney transplants between 1995 and 2003.

None of the patients had diabetes before their kidney transplant. Compared to other anti-rejection drugs, sirolimus was associated with a 36 percent to 66 percent increased risk of diabetes after transplant.

"We demonstrated a robust association between sirolimus and diabetes after transplantation in a large group of kidney transplant recipients in the United States. The risk of diabetes was independent of other factors that are known to increase the risk of diabetes," Dr. John S. Gill, of the University of British Columbia in Vancouver, Canada, said in a prepared statement.

The study was expected to be published in the July issue of the Journal of the American Society of Nephrology.

"Sirolimus is a newer type of anti-rejection drug that has not been associated with diabetes in transplant recipients. However, a number of animal studies and small clinical studies have suggested that sirolimus may increase the risk of diabetes," Gill noted.

This is the first large clinical study to suggest this association and indicates that more research is needed "to further clarify that risk of diabetes in sirolimus-treated patients."

Diabetes is a serious and increasingly common complication following kidney transplantation. Risk factors include age, race/ethnicity and obesity.

"Patients who develop diabetes after transplantation have roughly the same risk of transplant failure as patients who develop acute transplant rejection," Gill said.

More information

The National Kidney Foundation has more about kidney transplantation.



-- Robert Preidt



SOURCE: American Society of Nephrology, news release, May 22, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Anti-rejection drug may increase risk of diabetes after kidney transplant
2. Study provides hope that some transplant patients could live free of anti-rejection drugs
3. Gamma Labs to Boost Testosterone At World Series of Poker In Las Vegas
4. Gum Disease Might Boost Cancer Risk
5. New Friendship Cottage Cheese Boosts Digestive & Bone Health
6. Combo Kidney-Pancreas Transplant Boosts Survival in Diabetics
7. Dynatronics Acquisitions Boost Sales 80 Percent in Third Quarter
8. Excess Drinking Boosts Cardiovascular Disease Risk
9. UT Southwestern researcher: Supplemental breast ultrasound boosts cancer detection
10. Gene Variant Boosts Risk of Severe Diabetic Eye, Kidney Diseases
11. Obesity-Related Inflammation Boosts Heart Risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA ... the Road To Recovery® program to drive cancer patients to and from their cancer ... ensure the highest quality of life and ongoing independence. Getting to and from ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... People across ... in Genome magazine’s Code Talker Award, an essay contest in which patients and their ... award to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty ... Barry M. Weintraub as a prominent plastic surgeon and the network’s newest partner. ... and the most handsome men, look naturally attractive. Plastic surgery should be invisible.” ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital ... area economy by obtaining investment capital for emerging technology companies. SCP has ... have already resulted in more than a million dollars of capital investment for ...
(Date:6/24/2016)... ... 24, 2016 , ... Venture Construction Group (VCG) sponsors Luke’s Wings ... 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. ... service members that have been wounded in battle and their families. Venture Construction Group ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, ... less invasive and more durable cerebrospinal fluid treatments, ... funding.  The Series-A funding is led by Innova ... Fund, and other private investors.  Arkis, new financing ... instrumentation and the market release of its in-licensed ...
(Date:6/23/2016)... startling report released today, National Safety Council research shows ... plan to eliminate prescription opioid overdoses. Prescription Nation ... the worst drug crisis in recorded U.S. history, assigned a "Making ... , New Mexico , Tennessee ... states, three – Michigan , Missouri ...
(Date:6/23/2016)... WAYNE, Pa. , June 23, 2016 ... provider, will launch its next generation clinical outcomes platform, Bracket ... DIA Meeting held on June 26 – 30, 2016 in ... 6.0, the first electronic Clinical Outcome Assessment product of its ... DIA Booth #715. Bracket eCOA 6.0 is a ...
Breaking Medicine Technology: