Navigation Links
Anti-Rejection Drug May Boost Diabetes in Kidney Transplant Patients
Date:5/29/2008

Those treated with sirolimus faced up to 66% increased risk of disease after operation

THURSDAY, May 29 (HealthDay News) -- Treatment with the anti-rejection drug sirolimus may lead to increased risk of diabetes in kidney transplant patients, say researchers who analyzed data on about 20,000 Medicare patients who had kidney transplants between 1995 and 2003.

None of the patients had diabetes before their kidney transplant. Compared to other anti-rejection drugs, sirolimus was associated with a 36 percent to 66 percent increased risk of diabetes after transplant.

"We demonstrated a robust association between sirolimus and diabetes after transplantation in a large group of kidney transplant recipients in the United States. The risk of diabetes was independent of other factors that are known to increase the risk of diabetes," Dr. John S. Gill, of the University of British Columbia in Vancouver, Canada, said in a prepared statement.

The study was expected to be published in the July issue of the Journal of the American Society of Nephrology.

"Sirolimus is a newer type of anti-rejection drug that has not been associated with diabetes in transplant recipients. However, a number of animal studies and small clinical studies have suggested that sirolimus may increase the risk of diabetes," Gill noted.

This is the first large clinical study to suggest this association and indicates that more research is needed "to further clarify that risk of diabetes in sirolimus-treated patients."

Diabetes is a serious and increasingly common complication following kidney transplantation. Risk factors include age, race/ethnicity and obesity.

"Patients who develop diabetes after transplantation have roughly the same risk of transplant failure as patients who develop acute transplant rejection," Gill said.

More information

The National Kidney Foundation has more about kidney transplantation.



-- Robert Preidt



SOURCE: American Society of Nephrology, news release, May 22, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Anti-rejection drug may increase risk of diabetes after kidney transplant
2. Study provides hope that some transplant patients could live free of anti-rejection drugs
3. Gamma Labs to Boost Testosterone At World Series of Poker In Las Vegas
4. Gum Disease Might Boost Cancer Risk
5. New Friendship Cottage Cheese Boosts Digestive & Bone Health
6. Combo Kidney-Pancreas Transplant Boosts Survival in Diabetics
7. Dynatronics Acquisitions Boost Sales 80 Percent in Third Quarter
8. Excess Drinking Boosts Cardiovascular Disease Risk
9. UT Southwestern researcher: Supplemental breast ultrasound boosts cancer detection
10. Gene Variant Boosts Risk of Severe Diabetic Eye, Kidney Diseases
11. Obesity-Related Inflammation Boosts Heart Risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... 2016 , ... Conventional wisdom preaches the benefits of moderation, whether it’s a ... the bar too high can result in disappointment, perhaps even self-loathing. However, those who ... , Research from PsychTests.com reveals that behind the tendency to set ...
(Date:6/24/2016)... ... 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. In ... benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued ... Sickle Cell Disease (SCD) is a disorder of the red blood cells, which can ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are recognized ... this recognition are considered among the top 2 percent of lawyers practicing within the ... this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, Burt ...
(Date:6/24/2016)... ... 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join ... wage raise to $12 an hour by 2020 and then adjusting it yearly to increase ... of the minimum wage, assure the wage floor does not erode again, and make future ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... is proud to recognize Dr. Barry M. Weintraub as a prominent plastic surgeon ... beautiful women in the world, and the most handsome men, look naturally attractive. ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 27, 2016 Jazz Pharmaceuticals ... waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of ... acquisition of Celator Pharmaceuticals, Inc. ("Celator"; Nasdaq: ... p.m. (Eastern Daylight Time). As previously announced ... into a definitive merger agreement under which Jazz Pharmaceuticals ...
(Date:6/24/2016)... SOUTH SAN FRANCISCO, Calif. , June 24, ... GBT ), a biopharmaceutical company developing novel ... with significant unmet needs, today announced the closing ... 6,400,000 shares of common stock, at the public ... the shares in the offering were offered by ...
(Date:6/24/2016)... June 24, 2016 Dehaier Medical Systems Ltd. ... which develops, markets and sells medical devices and wearable ... signed a strategic cooperation agreement with Hongyuan Supply Chain ... Chain") on June 20, 2016, to develop Dehaier,s new ... cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s sales ...
Breaking Medicine Technology: