Navigation Links
Anti-Muellerian hormone predicts IVF success
Date:2/11/2013

Chevy Chase, MD Women with a high concentration of anti-Mllerian hormone stand a better chance of giving birth after in vitro fertilization, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

Anti-Mllerian hormone (AMH) is produced by the ovaries. The study found women with high AMH levels were 2.5 times more likely to have a successful IVF cycle than women of a similar age with low levels of the hormone. AMH levels were a predictor of pregnancy and live birth, even when the mother's age and egg production were taken into account.

Although a growing body of research has pinpointed AMH levels as an indicator of the number of eggs remaining in a woman's ovaries, this study is the first to demonstrate AMH levels are directly connected to birth and pregnancy rates, regardless of the number of eggs retrieved.

"For women who are struggling to get pregnant, a high AMH level should be very reassuring," said Thomas Brodin, MD, of Uppsala University in Sweden and lead author of the study. "High levels of this hormone mean there is a greater chance they have plenty of healthy eggs remaining to support a pregnancy."

Researchers concluded high AMH levels are associated with successful IVF treatment because the hormone levels reveal important information about the quality as well as the quantity of eggs left in a woman's ovaries. Women who have high AMH levels are likely to have a high proportion of eggs capable of developing into healthy embryos, Brodin said.

The prospective cohort study tracked 892 women who underwent IVF treatment at the Carl von Linn Clinic in Uppsala between 2008 and 2011. The participants underwent a total of 1,230 IVF cycles. AMH levels in the participants' blood were measured prior to treatment.

The study found that women were more likely to have a successful treatment outcome as their AMH levels increased. Women who had AMH levels above 2.94 ng/ml had the highest birth rates. The effect leveled out when AMH levels surpassed 5 ng/ml.

Although researchers did not find a cut-off point below which women could not get pregnant, IVF success rates dropped substantially as AMH levels declined. Among the study participants who had AMH levels below 0.2 ng/ml, 53 IVF cycles resulted in only 18 embryo transfers and the birth of three children.

The study found reason for optimism among women who have polycystic ovary syndrome, a condition normally associated with ovulation problems. Women who have this condition tend to have high AMH levels.

"Our data suggests women who have polycystic ovaries are likely to be good candidates for IVF," Brodin said. "Along with high AMH levels, this group tends to have a significant supply of eggs remaining in the ovaries."


'/>"/>

Contact: Jenni Glenn Gingery
jgingery@endo-society.org
301-941-0240
The Endocrine Society
Source:Eurekalert

Related medicine news :

1. Study finds hormones can change the breasts genetic material
2. Test for hormone-disrupting chemicals gets global seal of approval
3. Love Hormone May Aid Womens Recovery After Childbirth
4. New hormone therapy shows promise for menopausal symptoms in animal model
5. Hormone Replacement Clinic, Renew Health and Wellness Opens in Richmond, Virginia. New Center Specializes in Anti-Aging Therapies for both Women and Men.
6. Hormone Replacement Clinic, Renew Health and Wellness Opens in St. Louis, Missouri Area. New Center Specializes in Anti-Aging Therapies for both Women and Men.
7. Too Little Sleep Spurs Appetite-Boosting Hormones: Study
8. High hormone levels put young black males at risk for cardiovascular disease
9. Could Hormone Spray Help Men Stay, Not Stray?
10. Feel-good hormone helps to jog the memory
11. Pregnancy Hormone Shows Promise as Heart Failure Drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... , ... The Visiting Nurse Association (VNA) of Somerset Hills is proud to ... unique items from across the nation, this holiday-themed event will raise funds and awareness ... VNA. The boutique will be open Saturday, November 4 (10:00 a.m. – 5:00 ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in agile ... a contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise ... use of Agile methodologies in a consistent and high value manner across CMS ...
(Date:10/12/2017)... New Orleans, LA (PRWEB) , ... October 12, 2017 , ... ... fitness centers in the U.S., announced today its plans to open a flagship location ... club will occupy the former Rooms To Go store next to Office Depot in ...
(Date:10/12/2017)... Rockville, Maryland (PRWEB) , ... October 12, 2017 ... ... a magnetic drug delivery system that we intend to develop to enable prevention ... regimens can lead to severe hearing loss, especially in pediatric patients. For cisplatin, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned ... Michigan’s 2017 Best and Brightest in Wellness® by Best and Brightest. OnSite Wellness ... on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at the Henry ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... , Oct. 2, 2017 The Rebound mobile app ... struggle to reverse the tide of prescription drug addiction. The ... their medicine intake and stepping down their dosage in a ... launch in December 2017; the first 100,000 people to sign ... at http://www.rebound-solution.com/ ...
(Date:9/27/2017)... , Sept. 27, 2017  Commended for their devotion to ... awards. Ranked as number one in the South Florida Business ... in Inc. 5000 yearly list, the national specialty pharmacy has ... Armando Bardisa will soon be honored by SFBJ as ... Set to receive his award in October, ...
(Date:9/25/2017)... 25, 2017  EpiVax, Inc., a leader in ... immune-engineering today announced the launch of EpiVax Oncology ... personalized therapeutic cancer vaccines. EpiVax has provided $500,000 ... to enabling technologies to the new precision immunotherapy ... EpiVax Oncology as Chief Executive Officer. Gad brings ...
Breaking Medicine Technology: