Navigation Links
Anti-Convulsant Aids Knee-Replacement Patients
Date:10/15/2007

Pregabalin reduced pain, increased range of motion, study found

MONDAY, Oct. 15 (HealthDay News) -- The anti-convulsant drug pregabalin, given before and after surgery, helped reduce pain and promote mobility in patients having total knee replacement.

That study finding was presented Sunday at the annual meeting of the American Society of Anesthesiologists, in San Francisco.

The study, funded by drug maker Pfizer Inc., included 60 total knee replacement patients who were divided into two groups. One group received 300 milligrams of pregabalin two hours before surgery and 150 mg twice a day for 14 days after surgery. Patients in the other group received a placebo.

All the patients received pain medication through an epidural catheter during surgery and through a patient-controlled device after surgery.

In the 32 hours after surgery, patients who received pregabalin reported lower levels of pain and used less pain medication. Patients in the pregabalin group also had a higher range of knee motion when they were discharged from the hospital -- 84 degrees versus 76 degrees for patients in the placebo group. A knee-motion range of at least 83 degrees is required to climb stairs.

"When you can walk up and down stairs, it makes a huge difference in patient quality of life," and improved range of motion also promotes quicker completion of post-surgery rehabilitation, said study author Dr. Asokumar Buvanendran, director of orthopedic anesthesia and associate professor of anesthesiology at Rush University Medical Center in Chicago.

More information

The American Academy of Orthopaedic Surgeons has more about total knee replacement.



-- Robert Preidt



SOURCE: American Society of Anesthesiologists, news release, Oct. 14, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Mode Of Action Of The Anti-Convulsant Valproate
2. One in Three Heart Attack Patients Have No Chest Pains
3. Amphetamines Help Recovery of Stroke Patients
4. Painkillers Do Not Shorten Dying Patients Lives
5. Patients With Filariasis More Prone To HIV Infection
6. Glivec - New Hope For CMC Patients
7. HIV infected patients can travel safely abroad
8. New vaccine helps allergy and asthma patients
9. Doctors operate upon patients in candlelight- latest from the quake scene
10. New vaccine helps allergy and asthma patients
11. Are cancer patients being taken for a ride?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2016)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has written a new article ... Bible about helping to stop cancer. Yisrayl says there are too many suffering and dying ... and science industries will pay close attention and take action. The Pastor says that the ...
(Date:5/6/2016)... ... 06, 2016 , ... This Mother’s Day kicks off the start of an ... National Women’s Health Week takes place May 8-May 14. , Throughout the celebration, ... empower women to make their health a top priority. Women everywhere are being encouraged ...
(Date:5/6/2016)... ... May 06, 2016 , ... RowdMap, ... Blue Cross BlueShield and Former Principal Deputy Administrator at Centers for Medicare and ... Company; Steve Ondra, MD, Chief Medical Officer at Health Care Service Corporation (Blue ...
(Date:5/5/2016)... ... May 05, 2016 , ... ... select performance in the industry’s gold standard KLAS Performance Report, Epic ... Consulting report assessed organizations that specialize in consulting services for electronic health record ...
(Date:5/5/2016)... Illinois (PRWEB) , ... May 05, 2016 , ... ... its “deeming regulations” for electronic cigarettes, requiring e-cigarette manufacturers to submit their ... a “tobacco product,” apply to all vaping products that entered the market since ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... 3, 2016 BioNovus Innovations LLC and ... Advancing Medical Innovation (IAMI) today announced a new ... and medical devices. An agreement between ... to license, develop and commercialize medical innovations advanced ... "This partnership represents a significant advance in our ...
(Date:5/3/2016)...  As a teenager, an active and athletic ... his heart. He continued enjoying sports and recreation throughout ... heart was giving out and he was a few ... the Mesa, Arizona resident received ... heart transplant, the SynCardia TAH-t is the only approved ...
(Date:5/3/2016)... ORANGE COUNTY, Calif. , May 3, 2016  While you may be familiar with watching ... 4K resolution , also known as ultra-high-definition or 8MP in the Medical Industry.  Ampronix  is ... class manufacturer of innovative technology. Photo - http://photos.prnewswire.com/prnh/20160502/362730 ... ... ...
Breaking Medicine Technology: