Navigation Links
Anti-Convulsant Aids Knee-Replacement Patients
Date:10/15/2007

Pregabalin reduced pain, increased range of motion, study found

MONDAY, Oct. 15 (HealthDay News) -- The anti-convulsant drug pregabalin, given before and after surgery, helped reduce pain and promote mobility in patients having total knee replacement.

That study finding was presented Sunday at the annual meeting of the American Society of Anesthesiologists, in San Francisco.

The study, funded by drug maker Pfizer Inc., included 60 total knee replacement patients who were divided into two groups. One group received 300 milligrams of pregabalin two hours before surgery and 150 mg twice a day for 14 days after surgery. Patients in the other group received a placebo.

All the patients received pain medication through an epidural catheter during surgery and through a patient-controlled device after surgery.

In the 32 hours after surgery, patients who received pregabalin reported lower levels of pain and used less pain medication. Patients in the pregabalin group also had a higher range of knee motion when they were discharged from the hospital -- 84 degrees versus 76 degrees for patients in the placebo group. A knee-motion range of at least 83 degrees is required to climb stairs.

"When you can walk up and down stairs, it makes a huge difference in patient quality of life," and improved range of motion also promotes quicker completion of post-surgery rehabilitation, said study author Dr. Asokumar Buvanendran, director of orthopedic anesthesia and associate professor of anesthesiology at Rush University Medical Center in Chicago.

More information

The American Academy of Orthopaedic Surgeons has more about total knee replacement.



-- Robert Preidt



SOURCE: American Society of Anesthesiologists, news release, Oct. 14, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Mode Of Action Of The Anti-Convulsant Valproate
2. One in Three Heart Attack Patients Have No Chest Pains
3. Amphetamines Help Recovery of Stroke Patients
4. Painkillers Do Not Shorten Dying Patients Lives
5. Patients With Filariasis More Prone To HIV Infection
6. Glivec - New Hope For CMC Patients
7. HIV infected patients can travel safely abroad
8. New vaccine helps allergy and asthma patients
9. Doctors operate upon patients in candlelight- latest from the quake scene
10. New vaccine helps allergy and asthma patients
11. Are cancer patients being taken for a ride?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/16/2017)... Houston, TX (PRWEB) , ... August 16, 2017 , ... ... named as a Castle Connolly 2017 Top Doctor. The annual list identifies the nation’s ... row that Dr. Vitenas has made it to the top of Castle Connolly’s coveted ...
(Date:8/16/2017)... ... August 16, 2017 , ... SGNA Standards of Infection ... reprocessing cycle, both between patient procedures and before storage, is a requisite practice ... important to the prevention of disease transmission and nosocomial infection as cleaning and ...
(Date:8/16/2017)... ... August 16, 2017 , ... Richard Strawn’s new book ... the time of a cancer diagnosis, surgery and recovery, the Psalms provided encouragement ... many ways God shows love to those who are sick., Surgical Psalms contains ...
(Date:8/16/2017)... NJ (PRWEB) , ... August 16, 2017 , ... ... is offering an opportunity for men and women to train as hospice ... families dealing with life-limiting illness. For over 30 years, the agency has trained ...
(Date:8/16/2017)... ... 16, 2017 , ... Rollon Skin Care Ltd., ... recently announced the launch of two new skincare products, Prache Antiaging Cream and ... expensive plastic surgery or in-patient cosmetic dermatological procedures. , “Prache Antiaging Cream and ...
Breaking Medicine News(10 mins):
(Date:8/8/2017)... Second-quarter 2017 revenues of $876 million and ... operations Second-quarter 2017 Branded ... Second-quarter 2017 Sterile Injectables ... Second-quarter 2017 adjusted diluted earnings per ... $0.93 Second-quarter 2017 reported ...
(Date:8/7/2017)... Pharmacy, Inc. (NYSE: DPLO), the nation,s largest independent specialty pharmacy, ...  All comparisons, unless otherwise noted, are to the quarter ended ... Second Quarter 2017 Highlights include: Revenue ... 3.5% Total prescriptions dispensed of 220,000, compared ... 7.6% Gross profit per prescription dispensed ...
(Date:8/3/2017)... Aug. 3, 2017  Opioid addiction and other drugs ... healthcare costs and threatening outcomes, were problems taken on ... IVD industry that support them, met this week. This ... said that drugs of abuse, procalcitonin and acute kidney ... the organization,s 69th meeting in San Diego, ...
Breaking Medicine Technology: