Navigation Links
Anti-Clotting Drug as Good as Aspirin at Stopping Second Stroke

Cilostazol also resulted in fewer brain bleeds than aspirin, study finds

MONDAY, May 5 (HealthDay News) -- The anti-clotting drug cilostazol is as good as aspirin at preventing recurrent stroke and it causes less bleeding in the brain, a study by researchers at Peking University First Hospital in Beijing shows.

The trial included 360 patients stroke patients who took cilostazol for 12 to 18 months and 359 patients who took aspirin for the same length of time. Twelve patients in the cilostazol group and 20 patients in the aspirin group suffered recurrent stroke.

The researchers calculated that cilostazol reduced the risk of recurrent stroke by 38 percent, which is not statistically significant. But they also found that far fewer brain bleeding events occurred in the cilostazol group (one patient) than in the aspirin group (seven patients), which was statistically significant.

"The lower rates of ischemic and hemorrhagic stroke in the cilostazol group suggests that cilostazol might be a more effective and safer alternative to aspirin for Chinese patients with ischemic stroke; however, a larger phase III trial is required to confirm this," the researchers wrote.

Stroke is the second leading cause of death in China. While aspirin is effective for preventing recurrent stroke, Asian people are more likely than others to suffer brain bleeding when taking aspirin, and the incidence of such bleeds in China is higher than in high-income nations. Cilostazol works through a different mechanism than aspirin.

The study appears online Monday in The Lancet Neurology, and will be published in the June print edition of the journal.

"The implications of these results for clinicians are that they offer hope for a safer antiplatelet [anti-clotting] drug that is at least as effective as aspirin for use in patients with ischemic stroke," Dr. Graeme J. Hankey, department of neurology, Royal Perth Hospital in Australia, wrote in an accompanying editorial.

More information

The American Stroke Association outlines ways to prevent another stroke.

-- Robert Preidt

The Lancet Neurology, news release, May 5, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Anti-Clotting Drug Helps Infants With Heart Ills
2. Anti-Clotting Drug Trial Shortened by Bleeding Problems
3. Researchers identify molecules with interesting anti-clotting properties
4. New Anti-Clotting Drug Shows Promise in Heart Patients
5. Possible safer target for anti-clotting drugs found
6. Daily Aspirin May Reduce Breast Cancer Risk
7. Daily aspirin may reduce risk of common type of breast cancer
8. Aspirin-like compounds increase insulin secretion in otherwise healthy obese people
9. Will botox be the aspirin of the 21st century?
10. Aspirin Reduces Asthma Risk Among Older Women
11. Ibuprofen destroys aspirins positive effect on stroke risk
Post Your Comments:
Related Image:
Anti-Clotting Drug as Good as Aspirin at Stopping Second Stroke
(Date:12/1/2015)... ... December 01, 2015 , ... ... and hematology continuing medical education (CME), today announced that the first annual School ... New York. , “The prevention, detection and treatment of gastrointestinal cancers are undergoing ...
(Date:12/1/2015)... , ... December 01, 2015 , ... Growth in medical ... due to decreases in utilization of hospital and nonhospital care, according to a recent ... Medical Benchmarks for Louisiana, 16th Edition , found medical payments per claim with more ...
(Date:12/1/2015)... ... December 01, 2015 , ... ... images have been lifted as IMAGE Information Systems launches MED-TAB™ -- the world’s ... America Annual Meeting from November 29 to December 4, 2015. , MED-TAB ...
(Date:12/1/2015)... ... December 01, 2015 , ... ... Inc. (“Visage”), a wholly owned subsidiary of Pro Medicus Ltd. (ASX: PME), has ... the Radiological Society of North America (RSNA) 2015 annual meeting through December 3 ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... clinical solutions for the care management and population health arenas, is pleased to ... clinical and cost containment services, has successfully implemented the ACUITY Complete Care™ Management ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... , Dec. 2, 2015  A combination of detailed ... the first time in the surgical planning for separation of ... annual meeting of the Radiological Society of North ... --> Conjoined twins, or twins whose bodies are connected, ... rates are low and separating them through surgery is extremely ...
(Date:12/1/2015)... , Dec. 1, 2015  A large study ... drug tamoxifen while taking an antidepressant found no increased ... today in The Journal of the National Cancer Institute. ... Tamoxifen is a commonly prescribed generic drug taken by ... developing a recurrence. Tamoxifen is recommended for five years, ...
(Date:12/1/2015)... Wash. and VANCOUVER , ... Committee (DMC) meeting, OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI ... is continuing based on the pre-planned interim futility analysis ... review, no new safety issues were identified by the ... all analyses and final results are expected in the ...
Breaking Medicine Technology: