Navigation Links
Anti-Clotting Drug May Cause Severe Bleeding With No Benefit
Date:7/25/2011

Eliquis is a so-called Xa inhibitor, which is a class of anticoagulants that work by blocking factor X, a protein involved in blood clotting.

Over an average follow-up of eight months, 7.5 percent of the patients receiving Eliquis had a heart attack, suffered a stroke, or died, as did 7.9 percent of the patients receiving placebo, the researchers found.

In addition, 1.3 percent of those taking Eliquis had major bleeding, compared with 0.5 percent of those receiving the placebo, they noted.

Moreover, more patients taking Eliquis had bleeding into the brain and died from uncontrollable bleeding than patients receiving placebo, Alexander said.

Would a lower dose of Eliquis work? Alexander is skeptical. While it could reduce the risk of bleeding, he said he doubts more heart attacks, strokes or deaths would be prevented.

The trial was funded by Pfizer/Bristol-Myers Squibb, the makers of Eliquis.

Commenting on the study, Dr. Gregg C. Fonarow, a professor of cardiology at the University of California, Los Angeles, said that "each year more than 1.4 million men and women are admitted to hospitals in the United States with acute coronary syndromes."

Despite conventional therapy, patients with acute coronary syndromes remain at risk for recurrent cardiovascular events, Fonarow said.

A number of medications that prevent blood clots (known as antithrombotic drugs) "are being evaluated in patients with acute coronary syndromes to determine if they can further reduce cardiovascular event risk without substantially increasing the bleeding risk when added to conventional therapies," he said.

Apixaban and two other drugs, rivaroxaban (Xarelto) and dabigatran (Pradaxa), have been shown to provide significant benefit in reducing stroke and clots in patients with atrial fibrillation, where the benefit outweighs the bleeding risk, Fonarow said.

"However, this new study suggests that the use of apixaban, at least at the dos
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Tests to Measure Safety of Anti-Clotting Drugs of Limited Value
2. Extended use of anti-clotting drug helps some bedridden patients
3. New Anti-Clotting Drug May Work Better After Hip Replacement
4. Anti-clotting agent does not improve outcomes of patients with severe pneumonia
5. Obstructive Sleep Apnea in Kids May Have Genetic Cause
6. UCLA study reveals how genes interact with their environment to cause disease
7. Virus Unlikely to Cause Chronic Fatigue Syndrome
8. RSA Innovator NetClarity Solves Networking Problems Caused by HP and Cisco Divorce
9. Popular nanoparticle causes toxicity in fish, study shows
10. Genetic cause discovered for rare bleeding disorder
11. Contact Dermatitis Can Be Irritating, Especially When the Cause is a Mystery
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Anti-Clotting Drug May Cause Severe Bleeding  With No Benefit
(Date:9/21/2014)... Dallas, Texas (PRWEB) September 22, 2014 ... over the past decade, as it has become ... short-acting beta-agonists (SABAs), inhaled corticosteroids (ICSs), inhaled corticosteroids ... has also been facing increasing generic competition. However, ... and once-daily ICS and ICS/LABA therapies delivered by ...
(Date:9/21/2014)... 21, 2014 "I want to help ... back but haven’t the money for chiropractors," said an ... have such a product for myself." , The Stretch ... stretch the thigh muscles and align the spine properly. ... relieves discomfort of pinched nerves. Compact and easy to ...
(Date:9/21/2014)... women starting college understand the benefits of a healthy ... they aren,t confident they can follow through on these ... The study involved 268 female college freshmen enrolled ... Eating Right program. The students answered food-related questions such ... were very busy with school work, were very hungry ...
(Date:9/21/2014)... (PRWEB) September 21, 2014 Originally ... in 1996, GSK’s Flovent (fluticasone propionate) is a ... is used for the maintenance treatment of asthma ... available in two formulations, Diskus and HFA, which ... respectively. Flovent’s active ingredient, fluticasone propionate, can bind ...
(Date:9/21/2014)... 21, 2014 High in the rugged ... disabled and able-bodied athletes rafted the Colorado River, rode ... course in pursuit of outdoor adventure. At the September ... World T.E.A.M. Sports, disabilities proved to be no more ... the three stage event. , Each participating team of ...
Breaking Medicine News(10 mins):Health News:Spiriva Asthma Market (Tiotropium Bromide) Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 2Health News:Spiriva Asthma Market (Tiotropium Bromide) Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 3Health News:Spiriva Asthma Market (Tiotropium Bromide) Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 4Health News: College Women Can Use Food Strategies, Study Finds 2Health News:Flovent Asthma Market Sales & SWOT Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 2Health News:Flovent Asthma Market Sales & SWOT Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 3Health News:Flovent Asthma Market Sales & SWOT Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 4Health News:Disabled Athletes Excel at World T.E.A.M. Sports’ Adventure Team Challenge 2Health News:Disabled Athletes Excel at World T.E.A.M. Sports’ Adventure Team Challenge 3
... in Federal Funds Awarded to Reconstruct Devastating,Injuries;, ... HEIGHTS, Ill., April 17 Members of,the American ... pivotal role,over the next five years developing groundbreaking ... Iraq and Afghanistan. The U.S.,Department of Defense (DoD) ...
... for cosmetic purposes might also improve wound healing and ... scarred during combat. Dr. Adam Katz, plastic surgeon and ... conduct research in this area under the Armed Forces ... announce the formation of AFIRM, which has received more ...
... CARLSBAD, Calif., April 17 The National Center ... resource for autism research, education and family support,services ... Families are,flocking to NCARE resulting from the announcement ... is that families desperately need centralized,autism resources., ...
... With Information and,Best Practices Related to Upcoming ... April 17 The new Centers for,Medicare ... eliminate or,reduce payments for three hospital-acquired infections ... conference for healthcare executives and professionals,sponsored by ...
... The National,Association of Specialty Health Organizations ... Innovation Award. The recipient of the award,will ... through,innovative programs and practices., (Logo: ... for the specialty health industry, we felt ...
... April 17 MSA (NYSE: MSA ), the,global ... that protect people,s health and safety, announced today that ... live via the,Internet on Thursday, May 1, 2008 at ... Investors and interested parties will have the opportunity ...
Cached Medicine News:Health News:Plastic Surgeons Play Pivotal Role in War Injury Research 2Health News:Plastic Surgeons Play Pivotal Role in War Injury Research 3Health News:UVA Health System part of Armed Forces multi-million dollar effort to help soldiers 2Health News:California's First Non-profit Center for Autism Research, Education and Family Services 2Health News:APIC Conference to Address New CMS Regulations 2Health News:The National Association of Specialty Health Organizations to Recognize Excellence in Technology Education With Industry Award 2Health News:MSA Schedules First Quarter Earnings Webcast 2
(Date:9/19/2014)... According to the new ... therapy, Hydrotherapy), Accessories (Posture Mirror, Exercise Ball), Applications (Pediatric, ... Global Forecast to 2019" published by MarketsandMarkets, the global ... Million by 2019 from $14,240.0 Million in 2014, ... 2019. Browse 74 market data tables ...
(Date:9/19/2014)... Research and Markets has announced the ... Cancer, Diarrhea, Mental Disorder) Market - Forecast to 2023" ... this report, the human microbiome market is segmented by application, ... is expected to be valued as $294 million in 2019 ... within the forecast period of 2019-2023. The market is driven ...
(Date:9/19/2014)... Mich. , Sept. 19, 2014  Diplomat, the ... of David Dreyer to the Board of ... independent director and will also serve as chair of ... almost 30 years of accounting, financial, compliance and operating ... Mr. Dreyer has served as chief financial officer, chief ...
Breaking Medicine Technology:Physiotherapy Equipment Market Worth $19,786.3 Million by 2019 2Physiotherapy Equipment Market Worth $19,786.3 Million by 2019 3Physiotherapy Equipment Market Worth $19,786.3 Million by 2019 4Global Human Microbiome (Diabetes, Obesity, Autoimmune, Cancer, Diarrhea, Mental Disorder) Market - Forecast to 2023 2Global Human Microbiome (Diabetes, Obesity, Autoimmune, Cancer, Diarrhea, Mental Disorder) Market - Forecast to 2023 3David Dreyer Appointed to Diplomat Board of Directors 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: