Anti-Aging Drug Closer to Reality ( Scientists extend lifespan of female ...)

Anti-Aging Drug Closer to Reality

Date:10/1/2009

Scientists extend lifespan of female mice and thwart diseases of old age in both sexes

THURSDAY, Oct. 1 (HealthDay News) -- In a possible advance toward a treatment for aging in people, researchers report that by genetically modifying mice, they reduced their susceptibility to age-related disease and expanded the lifespan of female mice by 19 percent.

Scientists have known for decades that taking in fewer calories can extend lifespan in some animals, but they have yet to figure out why that is so. In this new study, published in the Oct. 2 issue of Science, researchers manipulated mouse genes so they wouldn't produce a protein known as S6K1, thereby mimicking the effects of a strict diet.

No one knows if trying something similar in humans would slow their aging, and male mice didn't gain a longer lifespan. But researchers are hopeful, especially since the mice seemed to suffer no ill effects.

The mice were "in general, happier and healthier. We added life to their years as well as years to their lives," said study co-author Dr. Dominic J. Withers, a professor at University College London in England.

In essence, he explained, researchers have found a "mechanism" connected to the benefits of eating little that could be manipulated by existing medications. "We are therefore closer to treatments for aging and age-related diseases," he said.

At issue is finding a way to replicate the benefits of a severely restricted diet. But, keeping extremely tight control on eating can be "arduous" on a long-term basis, Withers acknowledged.

Female mice lived for an average of 950 days, 19 percent longer than usual, were skinnier and had stronger bones. They appeared to be better protected against type 2 diabetes and also appeared to be smarter: They were more "inquisitive and exploratory," Withers noted.

"Even their T cells, an important part of the immune system, appeared more '
'/>"/>

1

GOOD

Page: 1 2
Related medicine news :

1. Proactive Wellness Centers, PLC and Dr. Lynese Lawson Launch an All New "Anti-Aging" Blog
2. Leading Anti-Aging Prescription RENOVA(R) Continues To Deliver Maximum Results
3. Reportlinker Adds Anti-aging Products and Services: The Global Market Report
4. Resvera Health Rx Launches All-Natural Resveratrol-Based Supplement with Anti-Aging and Disease-Fighting Properties
5. Denver-Based Acupuncturist, Dr. Martha Lucas, Releases New Book: Vanity Calamity: Your Guide to Cosmetic Acupuncture for Anti-aging
6. Key protein may explain the anti-aging and anti-cancer benefits of dietary restriction
7. World Anti-Aging Congress 2009 Defies Global Economic Downturn, Demonstrating Strength of Anti-Aging Medical Movement
8. Anti-aging cosmetic reduced wrinkles in clinical trial
9. Expose on Crimes Against Humanity as Perpetrated by the Gerontological Elite Asks Is Consensus in Anti-Aging Medical Intervention An Elusive Expectation or A Realistic Goal?
10. Perlabella Introduces a Highly Concentrated and Affordable Anti-Aging Skin Care Line
11. Glissandra Skincare Inc. Launches Website Showcasing New and Novel Anti-Aging Skincare Products

Post Your Comments:

(Date:12/16/2009)... to disease , , WEDNESDAY, Dec. 16 (HealthDay News) ... leprosy have been identified by scientists in Singapore ... than 10,000 DNA samples from leprosy patients and ... the important role that the innate immune response ... leprosy is not common, the discoveries have significant ...

(Date:12/16/2009)... could help ease health and environmental concerns about the ... for changing the behavior of nanoparticles in municipal sewage ... Their study was published in ACS, journal Environmental ... UK Centre for Ecology and Hydrology and colleagues note ... nanoparticles particles less than 1/1000th the width of ...

(Date:12/16/2009)... Planet-Friendly Organics, Solar-Powered Manufacturing and Sustainable Packaging at an Affordable ... ... Angeles, CA (PRWEB) December 16, 2009 -- Actively healthy families ... all natural skin care for their children as Episencial ... featuring the beloved artwork of The Very Hungry Caterpillar from ...

(Date:12/16/2009)... caution, though, that no direct link has been found, ... bacteria in food -- commonly linked to food poisoning ... might also be the cause of some urinary tract ... the bacteria in chicken from stores and restaurants and ... evidence that the germs were transmitted directly to the ...

(Date:12/16/2009)... and MassBio promote Massachusetts companies through annual marketing campaign ... ... 2009 -- BioSpace unveiled the 2010 Genetown™ Hotbed Campaign ... , , , ,Genetown is sponsored by MassBio ... device industries. The campaign places each entity’s brand on an ...

Breaking Medicine News(10 mins):Health News:Leprosy Genes Identified 2 Health News:Behavior modification could ease concerns about nanoparticles 2 Health News:New from Episencial: All Natural, Actively Healthy Skin Care for Babies, Kids and Planet Features Eric Carle's "The Very Hungry Caterpillar" 2 Health News:New from Episencial: All Natural, Actively Healthy Skin Care for Babies, Kids and Planet Features Eric Carle's "The Very Hungry Caterpillar" 3 Health News:New from Episencial: All Natural, Actively Healthy Skin Care for Babies, Kids and Planet Features Eric Carle's "The Very Hungry Caterpillar" 4 Health News:New from Episencial: All Natural, Actively Healthy Skin Care for Babies, Kids and Planet Features Eric Carle's "The Very Hungry Caterpillar" 5 Health News:Foodborne E. Coli Suspected in Urinary Tract Infections 2 Health News:Foodborne E. Coli Suspected in Urinary Tract Infections 3 Health News:Thriving Bioscience Region Leaves Its Mark 2

[0] Leprosy Genes Identified [0] Behavior modification could ease concerns about nanoparticles [1] New from Episencial: All Natural, Actively Healthy Skin Care for Babies, Kids and Planet Features Eric Carle's "The Very Hungry Caterpillar" [0] Foodborne E. Coli Suspected in Urinary Tract Infections [0] Thriving Bioscience Region Leaves Its Mark

... CHAPEL HILL, N.C., Sept. 13 "Profit, customers and,people ... the conference,Human Capital Management: Facing the Challenges of the ... taking care of your people, your people,will take care ... of your,business." At the recent HR-focused conference of ...

... now under development could enhance the design of sports ... sporting potential. , The models, more sophisticated and more ... produce unprecedentedly realistic simulations of how potential ball designs, ... , This data can then be harnessed by sports ...

... N.J., Sept. 12 The following is,a statement issued by ... CASSIDY, ON BEHALF OF ROSA ACUNA, RE: ... V. TURKISH, Today,s opinion is a stunning and surprising, ... Jersey. The opinion represents a,significant departure, in our judgment, from ...

... /PRNewswire-FirstCall/ - Transition Therapeutics Inc.,("Transition" or the ... developing therapeutics for disease indications,with large markets, ... year,ended June 30, 2007. Selected Highlights ... up to the date of this press ...

... EPI-Q, a leading healthcare,management consulting firm, announces today ... key appointment. EPI-Q, Inc. specializes in assisting life,sciences ... outcomes,and cost-effectiveness of patient care. Andrew Baker ... NY. Mr. Baker will have responsibility for global ...

... BEDFORD, Mass., Sept. 12 Hologic, ... of state-of-the-art diagnostic and,digital imaging systems directed ... statement, including a joint proxy,statement/prospectus, for a ... ), has become effective. The Company will ...

Broker a Suite of Research & Advisory Services to Enhance Human Resources Computer models help raise the bar for sporting achievement Historic Abortion Case; Acuna V. Turkish Transition Therapeutics Announces Fiscal 2007 Year End Financial Results EPI-Q Opens East Coast Office and Appoints Vice President-Business Development Hologic Sets Special Meeting of Stockholders to Vote on Proposed Merger with Cytyc Corporation

(Date:12/16/2009)... NASHVILLE, Tenn. , Dec. 16 ... medical cost management services, today commended two new ... from CT scans and other diagnostic imaging tests. ... essential to proper diagnosis and treatment," said Gregg ... these new studies offer more compelling evidence that ...

(Date:12/16/2009)... -- Wound Management Technologies, Inc. (OTC Bulletin ... specialty medical products, announced today that its ... productization of its patented orthopedic bone void ... to be introduced in Q3 2010, to ... multi-billion dollar international market. ,, "Resorbable Orthopedics ...

(Date:12/16/2009)... A new application developed ... clinical review of specialty pharmaceuticals has increased health ... reviewed while reducing costs. ,, AIM, a leading ... health plan clients representing over 35 million consumers ... WLP ), adapted the successful clinical ...

Breaking Medicine Technology:MedSolutions Applauds Renewed Focus on the Dangers of Radiation Exposure 2 MedSolutions Applauds Renewed Focus on the Dangers of Radiation Exposure 3 Wound Management Technologies, Inc. Targets Multi-Billion Dollar Biomaterials Market; Releases Update on Resorbable Orthopedics 2 Wound Management Technologies, Inc. Targets Multi-Billion Dollar Biomaterials Market; Releases Update on Resorbable Orthopedics 3 American Imaging Management's New Specialty Drug Program Delivers Immediate Results 2 American Imaging Management's New Specialty Drug Program Delivers Immediate Results 3 American Imaging Management's New Specialty Drug Program Delivers Immediate Results 4 NCR Embeds DigitalPersona U are U 28R 29 4500HD Fingerprint Sensor in New NCR RealPOS 28TM 29 70XRT Point of Sale Workstations 10017 1 NCR Embeds DigitalPersona U are U 28R 29 4500HD Fingerprint Sensor in New NCR RealPOS 28TM 29 70XRT Point of Sale Workstations 10017 2 45 000 excess deaths annually linked to lack of health insurance 3A Harvard study 57890 1 45 000 excess deaths annually linked to lack of health insurance 3A Harvard study 57890 2 Boston Scientific PROMUS 28R 29 and First Generation TAXUS 28R 29 Express 28R 29 Stents Continue Excellent Performance in SPIRIT III Trial 57889 1 Boston Scientific PROMUS 28R 29 and First Generation TAXUS 28R 29 Express 28R 29 Stents Continue Excellent Performance in SPIRIT III Trial 57889 2 Boston Scientific PROMUS 28R 29 and First Generation TAXUS 28R 29 Express 28R 29 Stents Continue Excellent Performance in SPIRIT III Trial 57889 3 Boston Scientific PROMUS 28R 29 and First Generation TAXUS 28R 29 Express 28R 29 Stents Continue Excellent Performance in SPIRIT III Trial 57889 4

[0] MedSolutions Applauds Renewed Focus on the Dangers of Radiation Exposure [0] Wound Management Technologies, Inc. Targets Multi-Billion Dollar Biomaterials Market; Releases Update on Resorbable Orthopedics [0] American Imaging Management's New Specialty Drug Program Delivers Immediate Results

... Diabetes Therapy Also Improved Glucose ... Day, SAN FRANCISCO, June 9 Amylin Pharmaceuticals,Inc. ... LLY ), and Alkermes, Inc.,(Nasdaq: ALKS ) ... showed the durable efficacy of exenatide once weekly, a,long-acting ...

... long-term, large-scale and,independent studies evaluating cardiovascular (CV) outcomes ... 9,300 patients taking AVANDIA(R),(rosiglitazone maleate) and provide more ... The Veterans Affairs Diabetes Trial,(VADT), through two separate ... is no evidence to suggest that use of ...

After One Year, Type 2 Diabetes Patients Taking Exenatide Once Weekly Sustained Improvements in Glycemic Control and Weight; DURATION-1 Presented at ADA 2008 Two Large, Independent Outcomes Trials Offer New Important Safety Information on Cardiovascular Effects of AVANDIA(R)

The TBR-360-1-GD is a large capacity upright style operating temperature +4C. It is specially designed refrigerators for the storage of blood in standard 500ml bags, complying with Australian Standar...

... precise requirements of blood banking and ... Equipment meets American Association of Blood ... (ANRC) and U.S. Food & Drug ... and platelet incubators feature alarm systems ...

Refrigerator specially designed for the storage of blood in standard 500ml bags, complying with Australian Standard AS3864 1997....

TBR-120-1-GD is large capacity upright style refrigerator with an operating temperature of +4C. It is a specially designed refrigerator for the storage of blood in standard 500ml bags, complying with...

Medicine Products:

Blood Storage Refrigerator TBR-360-1-GD Blood Bank Refrigerator 3626 Blood Storage Refrigerator TBR-160-1-GD Blood Storage Refrigerator TBR-120-1-GD

Anti-Aging Drug Closer to Reality( Scientists extend lifespan of female ...),Health