Navigation Links
Anthrax Vaccine Shows Promise in Monkeys
Date:1/20/2012

FRIDAY, Jan. 20 (HealthDay News) -- Monkeys vaccinated with an anthrax capsule vaccine were protected against lethal anthrax infection, a new study has found.

The anthrax capsule is a naturally occurring component of Bacillus anthracis, the bacterium that causes anthrax.

This is the first successful use of a non-toxin vaccine to protect monkeys from anthrax, which is regarded as one of the most serious bioterrorism threats, according to the U.S. Army scientists who conducted the study.

Bacillus anthracis produces three main components that enable it to cause harm -- lethal toxin, edema toxin and the capsule. During anthrax infection, the capsule surrounds the bacterium and protects it from destruction by the body's white blood cells.

In this study, the researchers found that the anthrax capsule vaccine induced anti-capsule antibody responses in both rabbits and monkeys. Vaccinated rabbits were not protected against anthrax spores, but many of the vaccinated monkeys did survive.

The study appears in the Jan. 20 print issue of the journal Vaccine.

Current human vaccines for anthrax are based on the protective antigen component of the anthrax toxins, but there are concerns about relying on a single antigen and about anthrax strains that may be vaccine resistant, said senior author Arthur Friedlander of the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).

"This is the first non-toxin anthrax vaccine shown to be protective in monkeys. In addition, this new capsule vaccine is expected to work against possible vaccine-resistant strains of anthrax, as well as in recipients whose immune systems may not respond to protective antigen alone," Friedlander said in a USAMRIID news release.

While the findings of the new study are promising, scientists note that research involving animals often fails to produce similar results in humans.

More information

The U.S. Centers for Disease Control and Prevention has more about anthrax.

-- Robert Preidt

SOURCE: U.S. Army Medical Research Institute of Infectious Diseases, news release, Jan. 12, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Poll: Hypothetical anthrax attack and antibiotics
2. Bacillus anthracis and Anthrax
3. Community storage of anthrax-preventing antibiotics should be determined by state
4. Natural killer cells could be key to anthrax defense
5. Anthrax capsule vaccine protects monkeys from lethal infection
6. Vaccine May Prevent TB in People With HIV
7. Vaccine Not Fail-Safe in Ongoing Mumps Outbreak
8. New strategy produces promising advance in cancer vaccines
9. Screens, Vaccine for HPV Less Beneficial in Older Women
10. New Technology Could Widen Reach of Vaccines
11. Texas-based consortium announces groundbreaking vaccine research program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... , ... December 09, 2016 , ... ... at The Pierre Hotel in New York, NY, on December 3rd, to benefit ... and physicians attended the annual event, which raised over $1 million - the ...
(Date:12/8/2016)... ... December 08, 2016 , ... The Florida Hospital Tampa Wound ... Medical Society (UHMS), the leading authority in hyperbaric medicine. This accreditation identifies the ... hospitals and facilities have earned this distinction. This is the second time the ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... Management (MTM), adherence, and other pharmacist-delivered patient care services, has announced the promotions ... Eric Hoessel to vice president of sales. , Litsinger joined Mirixa in ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... access for customers and employees that are both engaging and easy to use. ... Smart Technology, the software company revealed today its plans to roll out new ...
(Date:12/8/2016)... ... December 08, 2016 , ... California Senate Bill (SB) 863, signed into law ... in 2013 and 2014, according to CompScope™ Medical Benchmarks for California, 17th Edition ... to the study, medical payments per claim in California decreased 4 percent in 2013 ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... Research and Markets has announced the addition of the ... ... vaccines market to grow at a CAGR of 6.83% during the ... the growth prospects of the global travel vaccines market for 2016-2020. ... from the sales of various vaccines administered to actively immunize meningococcal ...
(Date:12/8/2016)... IRIDEX Corporation (NASDAQ: IRIX ) today ... common stock, $0.01 par value (the "Offering" with such shares ... final terms of the Offering will depend on market and ... be no assurance as to whether or when the Offering ... net proceeds it will receive from this offering for working ...
(Date:12/8/2016)... , Dec. 8, 2016  The global biosurgery ... 8.8% during the forecast period of 2016 to 2021. ... by 2021 from USD 18.21 billion in 2016. The ... rising incidences of sports related injuries and spinal problems, ... rising need of effective blood loss management. ...
Breaking Medicine Technology: