Navigation Links
Anthrax Vaccine Shows Promise in Monkeys
Date:1/20/2012

FRIDAY, Jan. 20 (HealthDay News) -- Monkeys vaccinated with an anthrax capsule vaccine were protected against lethal anthrax infection, a new study has found.

The anthrax capsule is a naturally occurring component of Bacillus anthracis, the bacterium that causes anthrax.

This is the first successful use of a non-toxin vaccine to protect monkeys from anthrax, which is regarded as one of the most serious bioterrorism threats, according to the U.S. Army scientists who conducted the study.

Bacillus anthracis produces three main components that enable it to cause harm -- lethal toxin, edema toxin and the capsule. During anthrax infection, the capsule surrounds the bacterium and protects it from destruction by the body's white blood cells.

In this study, the researchers found that the anthrax capsule vaccine induced anti-capsule antibody responses in both rabbits and monkeys. Vaccinated rabbits were not protected against anthrax spores, but many of the vaccinated monkeys did survive.

The study appears in the Jan. 20 print issue of the journal Vaccine.

Current human vaccines for anthrax are based on the protective antigen component of the anthrax toxins, but there are concerns about relying on a single antigen and about anthrax strains that may be vaccine resistant, said senior author Arthur Friedlander of the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).

"This is the first non-toxin anthrax vaccine shown to be protective in monkeys. In addition, this new capsule vaccine is expected to work against possible vaccine-resistant strains of anthrax, as well as in recipients whose immune systems may not respond to protective antigen alone," Friedlander said in a USAMRIID news release.

While the findings of the new study are promising, scientists note that research involving animals often fails to produce similar results in humans.

More information

The U.S. Centers for Disease Control and Prevention has more about anthrax.

-- Robert Preidt

SOURCE: U.S. Army Medical Research Institute of Infectious Diseases, news release, Jan. 12, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Poll: Hypothetical anthrax attack and antibiotics
2. Bacillus anthracis and Anthrax
3. Community storage of anthrax-preventing antibiotics should be determined by state
4. Natural killer cells could be key to anthrax defense
5. Anthrax capsule vaccine protects monkeys from lethal infection
6. Vaccine May Prevent TB in People With HIV
7. Vaccine Not Fail-Safe in Ongoing Mumps Outbreak
8. New strategy produces promising advance in cancer vaccines
9. Screens, Vaccine for HPV Less Beneficial in Older Women
10. New Technology Could Widen Reach of Vaccines
11. Texas-based consortium announces groundbreaking vaccine research program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2017)... ... 26, 2017 , ... The Centers for Advanced Orthopaedics (The ... Richard Robinson as chief operating officer (COO). In this role, Robinson brings more ... record of simplifying business processes and developing growth strategies to increase market share. ...
(Date:6/26/2017)... ... June 26, 2017 , ... A new ... the way women look and feel about themselves and their sexual encounters. A ... dysfunction and urinary leakage head on with a ground breaking medical technique aimed ...
(Date:6/26/2017)... ... June 26, 2017 , ... If ... are seeing lots of red these days. According to recent estimates, 75 – ... from medical coding errors(1). Some studies point to Electronic Health Records (EHR) with ...
(Date:6/26/2017)... ... June 26, 2017 , ... New patients with missing ... Cotey, with or without a referral. Dr. Cotey is a trusted dentist who has ... tooth replacement option. , Patients with missing teeth in Fitchburg, WI, are encouraged to ...
(Date:6/25/2017)... ... June 24, 2017 , ... Create a feel-good lyric music video in Final Cut Pro ... in the timeline and write in the lyrics to any song. ProLyric flies in the ... line of the text can be added modularly for optimal control. ProLyric makes editing any ...
Breaking Medicine News(10 mins):
(Date:6/8/2017)... Responding to Heath Ledger,s father,s recent call for ... Chris Cornell in May, the mental health watchdog group, ... psychiatric drug side effects search engine ... risks. The father of the late actor ... has called for tighter rules on prescription drugs. Speaking at ...
(Date:6/5/2017)... Cincinnati location of Diplomat Specialty Infusion ... been awarded a Top Workplaces 2017 honor by ... on an employee survey administered by WorkplaceDynamics, LLC, a research ... measures several aspects of workplace culture, including alignment, execution, and ... ...
(Date:5/30/2017)... Israel , May 30, 2017 DarioHealth Corp. (NASDAQ: ... big data solutions, today announced that it will be presenting at ... at 8:00 AM PT. Erez Raphael , CEO, of DarioHealth ... The conference will be held on June 6th & 7th, 2017 ... companies in the small / micro-cap space. ...
Breaking Medicine Technology: