Navigation Links
Anthrax Vaccine Shows Promise in Monkeys
Date:1/20/2012

FRIDAY, Jan. 20 (HealthDay News) -- Monkeys vaccinated with an anthrax capsule vaccine were protected against lethal anthrax infection, a new study has found.

The anthrax capsule is a naturally occurring component of Bacillus anthracis, the bacterium that causes anthrax.

This is the first successful use of a non-toxin vaccine to protect monkeys from anthrax, which is regarded as one of the most serious bioterrorism threats, according to the U.S. Army scientists who conducted the study.

Bacillus anthracis produces three main components that enable it to cause harm -- lethal toxin, edema toxin and the capsule. During anthrax infection, the capsule surrounds the bacterium and protects it from destruction by the body's white blood cells.

In this study, the researchers found that the anthrax capsule vaccine induced anti-capsule antibody responses in both rabbits and monkeys. Vaccinated rabbits were not protected against anthrax spores, but many of the vaccinated monkeys did survive.

The study appears in the Jan. 20 print issue of the journal Vaccine.

Current human vaccines for anthrax are based on the protective antigen component of the anthrax toxins, but there are concerns about relying on a single antigen and about anthrax strains that may be vaccine resistant, said senior author Arthur Friedlander of the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).

"This is the first non-toxin anthrax vaccine shown to be protective in monkeys. In addition, this new capsule vaccine is expected to work against possible vaccine-resistant strains of anthrax, as well as in recipients whose immune systems may not respond to protective antigen alone," Friedlander said in a USAMRIID news release.

While the findings of the new study are promising, scientists note that research involving animals often fails to produce similar results in humans.

More information

The U.S. Centers for Disease Control and Prevention has more about anthrax.

-- Robert Preidt

SOURCE: U.S. Army Medical Research Institute of Infectious Diseases, news release, Jan. 12, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Poll: Hypothetical anthrax attack and antibiotics
2. Bacillus anthracis and Anthrax
3. Community storage of anthrax-preventing antibiotics should be determined by state
4. Natural killer cells could be key to anthrax defense
5. Anthrax capsule vaccine protects monkeys from lethal infection
6. Vaccine May Prevent TB in People With HIV
7. Vaccine Not Fail-Safe in Ongoing Mumps Outbreak
8. New strategy produces promising advance in cancer vaccines
9. Screens, Vaccine for HPV Less Beneficial in Older Women
10. New Technology Could Widen Reach of Vaccines
11. Texas-based consortium announces groundbreaking vaccine research program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/13/2016)... ... February 13, 2016 , ... DDi , a Makro ... list for its expertise in eClinical Solutions. DDi has built its solution competency ... needs of global clients. DDi provides smarter technology for Clinical Development, Regulatory and ...
(Date:2/12/2016)... ... February 12, 2016 , ... ... a new initiative—the Siemens Foundation-PATH Ingenuity Fellowships—to develop the advanced skills needed ... top students from U.S. universities who will draw from Siemens’ deep knowledge ...
(Date:2/12/2016)... ... , ... Each year, the American Physical Therapy Association (APTA) offers a Combined ... Convention Center. Almost 10,000 physical therapists across the country are expected to attend this ... their chosen field and network with their colleagues. As in years past, HydroWorx ...
(Date:2/12/2016)... ... February 12, 2016 , ... The ThedaCare ... San Francisco General Hospital on April 5-7. The series is a multi-day, multi-workshop ... habits. The workshops cover a broad range of topics, including coaching skills, the ...
(Date:2/12/2016)... ... February 12, 2016 , ... AssureVest Insurance Group, a locally owned ... charity drive that will raise funds earmarked to purchase computers and software for Mrs. ... , “My school is in a low-income area and has more than 60 2nd ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... , Feb. 11, 2016 The primary ... and future adoption patterns on the usage of liquid ... the following: - Timeframe of liquid biopsy ... ctDNA, cfDNA and Evs—by organization type - Sample inflow ... types: blood, saliva, stool, serum, and so on. - ...
(Date:2/11/2016)... 11, 2016  Walgreens has committed to provide drug ... Washington, D.C. as part of a ... commended by shareholder advocacy organization As You Sow. ... "Many people hold on to unneeded drugs because they lack ... consequences." --> Conrad MacKerron , Senior Vice ...
(Date:2/11/2016)... Feb. 11, 2016  MiMedx Group, Inc. (NASDAQ: ... amniotic membrane and other birth tissues, human skin and ... and market advanced products and therapies, announced today that ... Global Healthcare Conference in New York ... Michael J. Senken , Chief Financial Officer and ...
Breaking Medicine Technology: