Navigation Links
Another reason to avoid high-fat diet -- it can disrupt our biological clock
Date:12/29/2008

Jerusalem, December 28, 2008 Indulgence in a high-fat diet can not only lead to overweight because of excessive calorie intake, but also can affect the balance of circadian rhythms everyone's 24-hour biological clock, Hebrew University of Jerusalem researchers have shown.

The biological clock regulates the expression and/or activity of enzymes and hormones involved in metabolism, and disturbance of the clock can lead to such phenomena as hormone imbalance, obesity, psychological and sleep disorders and cancer.

While light is the strongest factor affecting the circadian clock, Dr. Oren Froy and his colleagues of the Institute of Biochemistry, Food Science and Nutrition at the Hebrew University's Robert H. Smith Faculty of Agriculture, Food and Environment in Rehovot, have demonstrated in their experiments with laboratory mice that there is a cause-and-effect relation between diet and biological clock imbalance.

To examine this thesis, Froy and his colleagues, Ph.D. student Maayan Barnea and Zecharia Madar, the Karl Bach Professor of Agricultural Biochemistry, tested whether the clock controls the adiponectin signaling pathway in the liver and, if so, how fasting and a high-fat diet affect this control. Adiponectin is secreted from differentiated adipocytes (fat tissue) and is involved in glucose and lipid metabolism. It increases fatty acid oxidation and promotes insulin sensitivity, two highly important factors in maintaining proper metabolism.

The researchers fed mice either a low-fat or a high-fat diet, followed by a fasting day, then measured components of the adiponectin metabolic pathway at various levels of activity. In mice on the low-fat diet, the adiponectin signaling pathway components exhibited normal circadian rhythmicity. Fasting resulted in a phase advance. The high-fat diet resulted in a phase delay. Fasting raised and the high-fat diet reduced adenosine monophosphate-activated protein kinase (AMPK) level
'/>"/>

Contact: Jerry Barach
jerryb@savion.huji.ac.il
972-258-82904
The Hebrew University of Jerusalem
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Another Study Warns of Risk From Cardiac Surgery Drug
2. Employees Have Yet Another Reason To Lose Their Office Chairs In Favor Of A Treadmill Desk: Their Brain
3. Rowenta, Iron Manufacturer, Pits Marines, Quilters, Mothers and Daughters Against One Another to Help Iron Out Breast Cancer
4. Argentyn 23(R) Homeopathic First Aid Gel - Another Worlds First by Natural-Immunogenics Corp. for Healthcare Professionals
5. Philip Morris International Forced to Drop Another Concert Sponsorship; Philippines Health Department Applauded for Taking Action
6. Philip Morris International Caught in Philippines in Another Concert Sponsorship
7. Scientists identify another piece of the weight-control puzzle
8. Another new wrinkle in treating skin aging
9. Announcing Another Great Reason to Eat Chocolate
10. U.S. Patent Office Allows Another Significant VNUS Patent
11. Drugs, Doctors and Death: Heath Ledger Becomes Another Victim
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... Biostimulants are widely applied in turf ... ornamentals. These also help turf and ornamentals in absorption ... Turf, ornamentals, and flowers appear healthy and strong as ... increased from the last few years. The most dominating ... Europe, with around 40% share in 2013, and is ...
(Date:7/11/2014)... Researchers from The Miriam Hospital have found that ... significantly higher rates of smoking than those without ... less likely to attempt quitting than those without ... be sufficient for this population. The study and ... print in the American Journal of Public ...
(Date:7/11/2014)... 2014 The Corn Farming ... 2014 on the heels of fresh biofuel demand. The ... dedicate a larger share of their farmland to cultivating ... regulations required the mixing of 5.0% renewable content in ... the United States created a key export market for ...
(Date:7/11/2014)... FRIDAY, July 11, 2014 (HealthDay News) -- Prostate cancer ... disease, receive less effective treatment and die sooner if ... Researchers analyzed data from more than 41,200 American men ... and 2007. They followed them through 2009. Nearly 1,900 ... the two years before their prostate cancer was discovered. ...
(Date:7/11/2014)... 11, 2014 Riverside Health System became the ... in Virginia in late 2012 and now, in partnership with ... residents throughout the Williamsburg and Newport News region. , Also ... and benefits to independent older adults who wish to remain ... safety net of continuing care services as well as control ...
Breaking Medicine News(10 mins):Health News:Biostimulants Market in Turf and Ornamentals is Expected to Reach $ 3.8 Billion by 2018 - New Report by MicroMarket Monitor 2Health News:Biostimulants Market in Turf and Ornamentals is Expected to Reach $ 3.8 Billion by 2018 - New Report by MicroMarket Monitor 3Health News:Miriam Hospital study examines smoking prevalence 2Health News:Corn Farming in Canada Industry Market Research Report Now Available From IBISWorld 2Health News:Corn Farming in Canada Industry Market Research Report Now Available From IBISWorld 3Health News:Depression May Make It Harder to Beat Prostate Cancer 2Health News:Riverside and Williamsburg Landing Partner to Offer First of Its Kind Service to Virginians Who Want to Age in Place 2Health News:Riverside and Williamsburg Landing Partner to Offer First of Its Kind Service to Virginians Who Want to Age in Place 3Health News:Riverside and Williamsburg Landing Partner to Offer First of Its Kind Service to Virginians Who Want to Age in Place 4
... in Care, The experience of Ontario, Canada ... inequities but not education-related disparities in health care ... data on more than 25,558 residents of Ontario, ... covered by government, researchers find patient income levels ...
... related to heart disease, study shows , MONDAY, Sept. 21 ... at higher risk for having a heart attack, especially those ... both seasonal and the pandemic H1N1 swine flu are circulating ... are urged to get a seasonal flu shot and an ...
... of a specific gene variant shows a strong ... (UC) have demonstrated. In addition, the research indicates ... individuals harboring the gene variant can be further ... Stambrook, PhD, a professor in the department of ...
... , , SACRAMENTO, Calif., ... the Twin Rivers Unified School District will be able to ... created jointly by the California Dental Association Foundation, University of ... California HealthCare Foundation with start-up funding from Verizon. , ...
... 21 HTH Worldwide, a global health and safety ... are now available with sickness, accident and medical evacuation ... that include direct payment to participating doctors and hospitals ... the market today limit medical benefits to $25,000 or ...
... MARINA DEL REY, Calif., Sept. 21 Electronic medical records have ... Dr. Richard Merkin, CEO for Heritage Provider Network. HPN and its ... York have been eliminating waste and cutting costs while providing quality ... on the importance of integrating electronic medical records. , , ...
Cached Medicine News:Health News:September/October 2009 Annals of Family Medicine tip sheet 2Health News:September/October 2009 Annals of Family Medicine tip sheet 3Health News:September/October 2009 Annals of Family Medicine tip sheet 4Health News:September/October 2009 Annals of Family Medicine tip sheet 5Health News:September/October 2009 Annals of Family Medicine tip sheet 6Health News:Flu Can Raise Chances of Heart Attack 2Health News:Flu Can Raise Chances of Heart Attack 3Health News:Cancer predisposition from genetic variation shows strong gender bias 2Health News:New Tele-Health Care Project to Provide Dental Care to Underserved Communities in California 2Health News:New Tele-Health Care Project to Provide Dental Care to Underserved Communities in California 3Health News:New Tele-Health Care Project to Provide Dental Care to Underserved Communities in California 4Health News:HTH Worldwide Introduces Trip Protection Insurance With Major Medical Benefits 2Health News:Heritage Provider Network and Dr. Richard Merkin Highlight Cutting Health Care Costs Using Electronic Medical Records 2
(Date:7/10/2014)... , July 10, 2014  BC Technical, the largest ... MiE America , Inc., a leading provider of Siemens ... a long-term agreement naming BC Technical as the authorized ... MiE and BC Technical announced today that ... establish BC Technical as the service and systems provider ...
(Date:7/10/2014)... CVS Caremark Corporation (NYSE: CVS ) today announced ... of $0.275 (27.5 cents) per share on the corporation,s common ... holders of record on July 21, 2014. About ... helping people on their path to better health as the ... . Through the company,s more than 7,600 CVS/pharmacy stores; ...
(Date:1/15/2014)... , Jan. 15, 2014  Research and Markets ( http://www.researchandmarkets.com/research/6k27gw/dental ... Consumables Market - Global Industry Analysis, Size, Share, Growth, ... their offering. (Logo: http://photos.prnewswire.com/prnh/20130307/600769 ... are used on patients in order to treat dental ...
Breaking Medicine Technology:BC Technical Partners With MiE America To Be Authorized Provider Of Systems & Service 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3
... COTTAGE, N.Y., June 30 XTL,Biopharmaceuticals Ltd. (Nasdaq: ... patient randomization into its Phase 2b study of Bicifadine,-- ... the,treatment of diabetic neuropathic pain. 350 patients were randomized ... Company expects to,have the last patient complete the study ...
... new understanding of,the role played by the protein ... novel therapies to rebuild muscle tissue,damaged by disease, ... Institute for Cancer Research and Molecular Medicine at ... The researchers reported their findings, "Cdk9-55: A ...
Cached Medicine Technology:XTL Biopharmaceuticals Announces Completion of Patient Randomization Into the Bicifadine Phase 2b Clinical Trial for the Treatment of Diabetic Neuropathic Pain 2XTL Biopharmaceuticals Announces Completion of Patient Randomization Into the Bicifadine Phase 2b Clinical Trial for the Treatment of Diabetic Neuropathic Pain 3International Team Locates Key Player in Muscle Regeneration 2
Li Brand™ Surgical Hemostat. ("dissecting clamp") For NSV and other procedures....
... for applications such as vasectomy that ... ,The autoclavable handpiece with six-foot cord ... cautery electrodes, allowing the physician to ... wide variety of procedures., ,The 2201 ...
No Scalpel Vasectomy Hemostat 5 1/2" (14cm), smooth sharp point, curved, gold finger rings...
Li Brand™ Ringed Forceps. ("fixation clamp") For NSV and other procedures. Ring diameter approximately 3.5 mm. Manufactured exclusively for AMI to exacting specifications by a German company....
Medicine Products: