Navigation Links
Annals of Internal Medicine tip sheet for Oct. 2

1. Organizations Issue Comprehensive Guidelines for Treating Low Back Pain -- Clinicians Shouldnt Routinely Order Imaging and Other Diagnostic Tests

(Clinical Guidelines, p. 487.) (NOTE: This article is the subject of a video news release. Call for coordinates. A separate news release will be issued.)

2. Trial of Two Drugs Finds One Better at Suppressing Hepatitis B Virus

A 52-week, randomized trial involving 135 people with chronic hepatitis B virus (HBV) compared an older drug adefovir dipivoxil and a newer drug, telbivudine. Researchers found that telbivudine was better at suppressing blood virus levels than adefovir. A group of patients who were switched at 24 weeks from adefovir to telbivudine also showed reduced levels of the virus at 52 weeks compared to the group who continued on adefovir for 52 weeks. Researchers say the study results support the concept that maximizing viral suppression early in the course of therapy is linked to improved efficacy responses and less resistance, suggesting that agents providing the greatest viral suppression may be preferable as initial therapy. (This study is being released early online and will be published in the Dec. 4, 2007, print edition of Annals of Internal Medicine.)

3. All Screening Models for Breast Cancer-Causing Gene Mutations Work, with Reservations

Researchers applied seven prediction models to 3,342 families to determine an individual family members probability of having a BRCA1/BRCA2 mutation and compared the results with actual genetic tests for the mutations (Article, p. 441). They found that the seven models were similarly good at discriminating between people with a BRCA1/BRCA2 mutation and people without such mutations, but the models did make mistakes. Researchers found that predictions varied widely when the seven models were applied to one person, so genetic counselors may want to consider using several predictive models before recommending genetic testing. The genetic mutation tests are expensive, so clinicians use screening tests to try to determine if a person is likely to have the mutation before proceeding with the testing. An editorial writer notes that all the prediction models require information from family medical history and urges families to keep track of family members medical history and clinicians to ask about it (Editorial, p. 515).


Contact: Steve Majewski
American College of Physicians

Related medicine news :

1. The connection between strokes and the internal clock
2. Model of Internal Clocks Reveals How Jet Lag Disrupts the System
3. Researchers Discover Internal Compass of Immune Cells
4. 30-year-old Woman Survives internal Decapitation
5. Thin People may Be Internally Fat
6. Plant Growth Regulated by Both Internal Clock and External Light: Study
7. Nobel Prize for Medicine shared by Three scientists
8. Prince Charles lends support to Alternative Medicine
9. Alternative medicine more popular among HIV positive patients
10. Complementary and Alternative medicine
11. Pharmacies in for a dose of bitter medicine
Post Your Comments:
(Date:10/13/2015)... Boulder, Colorado (PRWEB) , ... October 13, 2015 ... ... launched the first high-tech foam roller with 11 hours of vibrating power. Tested ... to reduce recovery time and increase athletic performance. , Mark's background in sporting ...
(Date:10/13/2015)... , ... October 13, 2015 , ... The American Institutes ... college campus health staff caring for students who have experienced sexual assault and other ... the White House during the Violence Against Women Act's 21st anniversary. ...
(Date:10/13/2015)... M.A. (PRWEB) , ... October 13, 2015 , ... Sir ... service to the local Boston chapter of Ronald McDonald House Charities® (RMHC®). This ... that has supported Sir Grout of Greater Boston since its inception. , “We believe ...
(Date:10/13/2015)... ... ... "My friend's son suffers from eczema, and he had a horrible habit ... Platteville, Colo. "I came up with this kit as a way to prevent children ... child from rubbing or scratching his or her face. This protects sensitive skin from ...
(Date:10/13/2015)... , ... October 13, 2015 , ... ... anesthesia and pain management services, today announced its partnership with WPC Healthcare ... data from disparate systems and organizes the data into an aggregated data repository ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)... Oct. 13, 2015 Attracting mid- to large-sized medical ... to growing Baltimore into a major ... by the Maryland Technology Enterprise Institute (Mtech) . ... pieces in place to support innovation hubs and a thriving ... Mtech Baltimore. "This study is important because we believe ...
(Date:10/13/2015)... , Oct. 13, 2015  Graduate students ... care and medical research, will soon have the ... patient care – the drug discovery and development ... ) has collaborated with 10 leaders from academic ... "Making Medicines: The Process of Drug Development."  Lilly ...
(Date:10/13/2015)... SAN FRANCISCO , October 13, 2015 ... expected to reach USD 26.8 billion by 2022, according ... Anesthesia and respiratory devices, owing to their capability to ... expected to witness a substantial growth. --> ... reach USD 26.8 billion by 2022, according to a ...
Breaking Medicine Technology: