Navigation Links
Annals of Internal Medicine tip sheet for Oct. 2
Date:10/1/2007

1. Organizations Issue Comprehensive Guidelines for Treating Low Back Pain -- Clinicians Shouldnt Routinely Order Imaging and Other Diagnostic Tests

(Clinical Guidelines, p. 487.) (NOTE: This article is the subject of a video news release. Call for coordinates. A separate news release will be issued.)


2. Trial of Two Drugs Finds One Better at Suppressing Hepatitis B Virus

A 52-week, randomized trial involving 135 people with chronic hepatitis B virus (HBV) compared an older drug adefovir dipivoxil and a newer drug, telbivudine. Researchers found that telbivudine was better at suppressing blood virus levels than adefovir. A group of patients who were switched at 24 weeks from adefovir to telbivudine also showed reduced levels of the virus at 52 weeks compared to the group who continued on adefovir for 52 weeks. Researchers say the study results support the concept that maximizing viral suppression early in the course of therapy is linked to improved efficacy responses and less resistance, suggesting that agents providing the greatest viral suppression may be preferable as initial therapy. (This study is being released early online and will be published in the Dec. 4, 2007, print edition of Annals of Internal Medicine.)


3. All Screening Models for Breast Cancer-Causing Gene Mutations Work, with Reservations

Researchers applied seven prediction models to 3,342 families to determine an individual family members probability of having a BRCA1/BRCA2 mutation and compared the results with actual genetic tests for the mutations (Article, p. 441). They found that the seven models were similarly good at discriminating between people with a BRCA1/BRCA2 mutation and people without such mutations, but the models did make mistakes. Researchers found that predictions varied widely when the seven models were applied to one person, so genetic counselors may want to consider using several predictive models before recommending genetic testing. The genetic mutation tests are expensive, so clinicians use screening tests to try to determine if a person is likely to have the mutation before proceeding with the testing. An editorial writer notes that all the prediction models require information from family medical history and urges families to keep track of family members medical history and clinicians to ask about it (Editorial, p. 515).


'/>"/>

Contact: Steve Majewski
smajewski@acponline.org
215-351-2514
American College of Physicians
Source:Eurekalert

Related medicine news :

1. The connection between strokes and the internal clock
2. Model of Internal Clocks Reveals How Jet Lag Disrupts the System
3. Researchers Discover Internal Compass of Immune Cells
4. 30-year-old Woman Survives internal Decapitation
5. Thin People may Be Internally Fat
6. Plant Growth Regulated by Both Internal Clock and External Light: Study
7. Nobel Prize for Medicine shared by Three scientists
8. Prince Charles lends support to Alternative Medicine
9. Alternative medicine more popular among HIV positive patients
10. Complementary and Alternative medicine
11. Pharmacies in for a dose of bitter medicine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2017)... ... ... past six years, Lightning Labels has sent out a call for users of its custom ... creativity of their designs. Submissions this year were open from May 18 to July 1 ... winners of the sixth annual Photo Contest, along with the prizes they've received:, ...
(Date:8/22/2017)... ... August 22, 2017 , ... “Wilderness Voices”: a collection ... travel. “Wilderness Voices” is the creation of published author, Martha McKown, an ordained ... was inspired as a very young child when her older sisters studied High School ...
(Date:8/22/2017)... ... , ... TopConsumerReviews.com recently gave a best-in-class 5-star rating to Energy NADH, a ... of modern life continually makes more demands on time and energy, people are finding ... people in vicious high/low cycles and can also cause long term health issues. More ...
(Date:8/21/2017)... ... August 22, 2017 , ... ... I. Stevens as a 2017-2018 inductee into its VIP Woman of the ... NAPW is the nation’s leading networking organization exclusively for professional women, boasting more ...
(Date:8/21/2017)... ... 2017 , ... Marathon running has surged in popularity in ... running increases exposure to ultraviolet radiation, a carcinogen that promotes skin cancer. Studies ... half may be adequately protecting themselves with proper clothing and sunscreen. , ...
Breaking Medicine News(10 mins):
(Date:7/27/2017)... Holdings, Inc. (NYSE and SIX: ZBH) today reported financial results ... reported second quarter net sales of $1.954 billion, an ... an increase of 2.1% on a constant currency basis.  ... LDR Holding Corporation acquisition, second quarter 2017 revenues decreased ... on a constant currency basis. ...
(Date:7/26/2017)... Colo. , July 26, 2017 E.I. ... Guttridge and the Bimini SharkLab to custom design the worlds ... images of sharks in their native habitat. In preparation ... Discovery Channel,s Shark Week, Dr. Guttridge approached EIMI ... take pregnancy diagnosis directly to hammerhead sharks underwater. ...
(Date:7/26/2017)... Sancilio Pharmaceuticals Company, Inc. (SPCI) today announced ... Altemia TM , an oral therapy for pediatric patients ... (SCD). The SCOT Trial, is a double-blind, placebo-controlled, dose-finding, ... Altemia TM in pediatric patients aged 5-17 years ... "The completion of ...
Breaking Medicine Technology: