Navigation Links
Animal thyroid extract as effective as T4 in treating hypothyroidism
Date:6/17/2013

San Francisco, CA Desiccated thyroid extract (DTE), derived from crushed preparations of animal thyroid glands, is a safe and effective alternative to standard T4 therapy in hypothyroid patients, a new study finds. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

In adults, untreated hypothyroidism leads to poor mental and physical performance. It also can cause high blood cholesterol levels that can lead to heart disease. The condition is treated with Levothyroxine, a synthetic (laboratory-made) form of T4 that is identical to the T4 the thyroid naturally makes. Before the advent of synthetic thyroxine, patients with hypothyroidism were treated with DTE, which contains both T4 and the active thyroid hormone T3. Many patients claim they do not feel as well on T4 alone without the additional T3 hormone.

"While thyroid experts recommend T4 alone for treatment of hypothyroidism, until now there have not been any randomized double-blind studies to compare the clinical effectiveness of synthetic T4 with DTE," said Thanh Hoang, of the Naval Medical Center in Portsmouth, Virginia. "We found that DTE is a safe and effective alternative to the standard T4 therapy. Furthermore, DTE caused modest weight loss compared to T4 alone."

In this study, researchers investigated the effectiveness of DTE compared to Levothyroxine (L-T4) in 70 hypothyroid patients. Patients were randomized to either DTE or L-T4 for 16 weeks and then crossed-over for the same duration. Study subjects underwent biochemical and neurocognitive tests along with measurements of symptoms and mental health at baseline and at the end of each treatment period.

DTE therapy did not result in a significant improvement in quality of life, but did cause modest weight loss and nearly half of the study patients expressed preference for DTE over L-T4.

"Providers may now have an additional option for the treatment of hypothyroidism in patients who are not satisfied with standard T4 therapy," said Hoang. "DTE could be considered for hypothyroid patients who still have symptoms despite normal thyroid blood tests while on T4 therapy."


'/>"/>

Contact: Aaron Lohr
alohr@endocrine.org
240-482-1380
The Endocrine Society
Source:Eurekalert

Related medicine news :

1. American Farmer to Feature Lallemand Animal Nutrition in Upcoming Episode on RFD-TV, Produced by DMG Productions
2. Dallas’ Park Cities Pet Sitter, Inc. will Participate in the NAPPS “Presents 4 Pets” Campaign in Honor of the Humane Society of the United States’ Animal Shelter Appreciation Week
3. China Animal Vaccine Industry 2012-2015 - Market Research Report Available at MarketResearchReports.Biz
4. First Vegetarian School in Nation Visits Catskill Animal Sanctuary
5. China Animal Vaccine Market Analysis to 2017 in New Research Report at ReportsnReports.com
6. Genomic assay as an alternative to animal testing
7. Protein protects against breast cancer recurrence in animal model
8. Animal Emergency & Referral Center of Minnesota Helps Cat
9. Candidate drug provides benefit in SMA animal models
10. Health Professionals Ask President Obama and FDA to End Non-Therapeutic Use of Antibiotics in Animal Agriculture in a Letter Co-Sponsored by Health Care Without Harm
11. Discount Diva Duds Is Excited To Announce Their Partnership with 100 Plus Animal Rescue, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... , ... February 08, 2016 , ... If you are ... to handle, you are not alone. According to the Center for Disease Control and ... stroke, type 2 diabetes and certain types of cancer, some of the leading causes ...
(Date:2/8/2016)... ... February 08, 2016 , ... Steve Helwig & Associates Insurance ... new community enrichment program, has teamed up with Citizens Opposed to Domestic Abuse in ... intimate abuse. To support all those victimized by the fear of violence in their ...
(Date:2/8/2016)... ... February 08, 2016 , ... Local insurance agency ... Venice, FL area, has initiated a fundraiser for a two year old little ... days after Christmas. To support this beautiful child who is facing life’s journey ...
(Date:2/8/2016)... (PRWEB) , ... February 08, ... ... and security executive networking and relationship-marketing firm, announced today that nominations will ... Information Security Executive® (ISE®) West Awards. , Awards include the Information ...
(Date:2/8/2016)... ... 2016 , ... Eating disorders and post-traumatic stress disorder (PTSD) ... men with eating disorders report a history of trauma, research suggests that it ... eating disorder. , At the 2016 iaedp Symposium, the workshop, “What Eating ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... , Feb. 5, 2016 ... of the "Global Obstetrics Partnering 2010-2016: ... profile to their offering. --> ... the "Global Obstetrics Partnering 2010-2016: Deal ... to their offering. --> Research ...
(Date:2/4/2016)... Feb. 4, 2016  Edwards Lifesciences Corporation (NYSE: ... structural heart disease and critical care monitoring, announced today ... (ASR) agreement with Morgan Stanley & Co. LLC to ... is part of the Company,s previously authorized program to ... stock.  --> --> ...
(Date:2/4/2016)... -- Worldwide Radiology Oncology surgical robot markets are ... systems provide a way to improve traditional open ... systems pinpoint the delivery of radiation precisely, eliminating ... problem previously, limiting the quantity of radiation that ... far beyond what has been available, promising a ...
Breaking Medicine Technology: