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Animal, human health benefits anticipated from university's premier biomedical instrument
Date:11/12/2013

MANHATTAN, Kan. -- A Kansas State University team recently received a nearly $1.3 million grant from the National Science Foundation's Major Research Institute for a biomedical instrument that is anticipated to help with breakthroughs in animal and human health as well as cancer treatment.

The instrument is a modified wide-bore 600-megahertz magnetic resonance imaging spectrometer that will be equipped with a custom imaging probe. It can heat specific cells in the body using a process called thermal cell therapy that mimics how the body uses fever to fight infections while simultaneously producing real-time, high-resolution images of the heat's effects on tumors and inflamed cells.

"There is not a single instrument in the U.S. with which you can heat specific living cells and then image those cells to see immediately what effects that heat has," said Stefan Bossmann, professor of chemistry. "With this, we can see heat therapy with cell therapy in action."

The instrument will be used to treat small animal patients with cancers, infections and other diseases. Heat therapy of large animals and humans is anticipated to follow. Patients are not harmed by the instrument, Bossmann said.

The technology may eventually enable personalized hyperthermia treatment for infectious diseases and cancers in both humans and animals.

"We're excited because now we can use the instrument's very high-resolution images to track the cells and see the effects that heat and cell mediated therapy have on the tumor," said Deryl Troyer, professor of anatomy and physiology. "The key is that as we get feedback from the instrument, we can fine-tune it and refine this treatment method to a greater extent."

The project includes Bossmann; Troyer; Leila Maurmann, nuclear magnetic resonance/instrumentation manager of the chemistry department; Punit Prakash, assistant professor of electrical and computer engineering; and Sanjeev Narayanan, associ
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Contact: Stefan Bossmann
sbossman@k-state.edu
785-532-6817
Kansas State University
Source:Eurekalert  

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