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Angioplasty with stents may be safe in long-term for low-risk heart patients
Date:6/22/2011

including high surgical risk due to health issues like chronic obstructive pulmonary disease or a severely calcified artery, older age, or a preference for the more minimally invasive procedure.

"The study provided a window into "real-world" experience and is reflective of what is seen in everyday clinical practice," Lee said.

In examining 30-day outcomes for patients in the study group, the team found no reports of cardiac death, stroke, re-clogging of the artery or blood clots forming related to the stent. Seven patients (3 percent) experienced a mild heart attack that can occur during the procedure. According to Lee, these are mild events with little long-term clinical impact.

Follow-up angiographs or heart images were available for 136 (62 percent) of the patients, which helped further track their heart health status.

At one year, the cumulative event-free survival rate for cardiac death was 97.7 percent, and the event-free rate for artery re-clogging was 92.9 percent.

Over the course of the study, 22 patients needed to be retreated due to the artery re-clogging, and this occurred mostly in the first year. Of those patients, 14 underwent a repeat angioplasty and eight had bypass surgery.

One of the most common side effects of angioplasty with stenting in the past has been the re-closing of the artery after treatment. Lee says that with drug-eluting stents, this is occurring less frequently.

"Our analysis found that the short-term outcomes were excellent," he said. "Patients who survived after the first year had very good long-term survival and a low incidence of retreatment."

At nearly four years, the event-free survival rate for cardiac death was 95.5 percent, and the event-free rate for re-clogging of the artery was 88.9 percent. Twenty of the 221 patients had died and nine deaths were cardiac-related.

"We found that this procedure had a low overall risk pro
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Contact: Rachel Champeau
rchampeau@mednet.ucla.edu
310-794-2270
University of California - Los Angeles Health Sciences
Source:Eurekalert

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