Navigation Links
Angioplasty Proves Reasonable Alternative to Bypass Surgery

But patients who received stents required more procedures to reopen arteries, study found

MONDAY, March 31 (HealthDay News) -- For patients with blockages in the left main coronary artery, percutaneous coronary intervention -- PCI, often referred to as angioplasty -- may be a viable alternative to bypass surgery.

"We focused on all-cause mortality and found no difference between PCI and surgery," Dr. Seung-Jung Park, senior author of the study and director of interventional cardiology at Asan Medical Center in Seoul, South Korea, said at a news conference.

However, the study also found that PCI patients who received stents -- tiny wire-mesh tubes used to prop open an artery -- had much higher rates of revascularization, a procedure needed to reopen arteries that had become clogged again. Bare metal stents had the highest rate of revascularization, the study found.

The findings were presented Monday in Chicago at a meeting of the Society for Cardiovascular Angiography and Interventions, in partnership with the American College of Cardiology, and published simultaneously March 31 in the New England Journal of Medicine.

The left main coronary artery provides most of the blood to the heart's left ventricle. Current guidelines recommend coronary artery bypass grafting (CABG) over percutaneous coronary intervention unless a previous graft has been performed.

And until more studies are conducted, CABG should remain the treatment of choice in these patients, the study authors stressed.

Percutaneous coronary intervention, which refers to a number of procedures used to treat arteries, is usually reserved for patients who aren't good candidates for surgery or who are protected by a previous bypass graft. A typical form of PCI -- angioplasty -- involves inserting a catheter into the artery to widen the vessel, and then hold it open with a stent.

But the development of coronary-artery stenting, especially with drug-eluting stents, has led researchers to reassess the role of PCI. Drug-eluting stents slowly release drugs that help keep the artery open.

Currently, there is limited long-term data comparing CABG and percutaneous coronary intervention with stents in patients with left main coronary artery disease.

For the new study, Park and his team compared 1,102 patients with unprotected left main coronary artery disease who underwent stent implantation (318 with bare metal stents and 784 with newer drug-eluting stents) with 1,138 patients who underwent CABG as 12 centers in Korea.

Overall, there were no major differences between the two groups in the risk of death or the risk of an outcome that included heart attack and stroke.

The next step, Park said, is a randomized trial comparing the two procedures.

More information

The American Heart Association has more on percutaneous coronary intervention.

SOURCES: March 31, 2008, teleconference with Seung-Jung Park, M.D., Ph.D., director of interventional cardiology, Asan Medical Center, Seoul, Korea; March 31, 2008, New England Journal of Medicine

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. 2 drugs equally effective for heart patients undergoing angioplasty, Mayo study finds
2. On 30th Anniversary, Angioplasty Celebrated as Modern Medical Breakthrough in Stopping Heart Attack
3. Angioplasty Equals Bypass Surgery for Heart Patients: Study
4. Are women at greater risk from angioplasty?
5. Delayed angioplasty -- big bucks, no bang
6. Doing Angioplasty Long After Heart Attack Still Worth It, Analysis Shows
7. The Elderly Can Be Candidates for Angioplasty, Stenting
8. Comparison of anticoagulants for angioplasty show similar outcomes
9. Anticoagulant Drugs Had Similar Outcomes After Angioplasty
10. FDA Approves First Anti-Psychotic for Kids
11. Nasal Anthrax Vaccine Proves Effective in Animal Study
Post Your Comments:
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture ... said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package ... Final Cut Pro X . Simply select a ProHand generator and drag it ...
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/24/2016)... Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... surgery procedures that most people are unfamiliar with. The article goes on to state ... procedures, but also many of these less common operations such as calf and cheek ...
(Date:6/24/2016)... ... 2016 , ... Marcy was in a crisis. Her son James, eight, was out of control. ... and physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. ... rocks at my other children and say he was going to kill them. If ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 VolitionRx ... of Dr. Edward Futcher to the ... effective June 23, 2016.Dr. Futcher was also appointed ... Governance Committees.  As a non-executive member of the ... and strategic counsel to VolitionRx in connection with ...
(Date:6/23/2016)... 23, 2016  MedSource announced today that it ... software solution of choice.  This latest decision demonstrates ... to their clients by offering a state-of-the-art electronic ... establishes nowEDC as the EDC platform of choice ... clients.  "nowEDC has long been a preferred EDC ...
(Date:6/23/2016)... 2016 Any dentist who has made an implant ... process. Many of them do not even offer this as ... high laboratory costs involved. And those who ARE able to ... a high cost that the majority of today,s patients would ... Parsa Zadeh , founder of Dental Evolutions Inc. and inventor ...
Breaking Medicine Technology: