Navigation Links
Anemia Drugs Hold Dangers for Kidney Patients
Date:5/5/2010

Study finds increased risks for potential deadly complications

WEDNESDAY, May 5 (HealthDay News) -- The powerful drugs used to fight anemia caused by kidney failure increase the risk for cardiovascular problems such as heart attack, a major study has found.

A meta-analysis of 27 trials, which included more than 10,000 people who were given the drugs, known as erythropoiesis-stimulating agents (ESAs), found that those who took the drugs at the highest dosages had a 51 percent increased risk for stroke and a 33 percent increased risk for thrombosis, or blockage of an artery. The study, by an international group of experts, was published online May 3 in Annals of Internal Medicine.

The increased risk for death (9 percent) and serious cardiovascular events such as heart attacks (15 percent) did not reach statistical significance, the analysis found.

The U.S. Food and Drug Administration has acted to control the use of ESAs marketed as Epogen, Procrit and Aranesp, which stimulate production of red blood cells to treat the anemia caused by kidney failure and cancer chemotherapy. The agency has added a "black box" warning of dangers to ESA labeling.

The new study adds emphasis to such moves, said Dr. Ajay K. Singh, an associate professor of medicine at Harvard Medical School and a nephrologist at Brigham and Women's Hospital in Boston.

"This meta-analysis shows increased risk with no benefit," Singh said. "The supposed benefit is that ESAs improve quality of life and make people feel better. This study suggests that these drugs, used at considerable cost, don't show any benefit in terms of those endpoints."

ESAs cost Medicare $2 billion a year, Singh said, making them the most expensive drugs in terms of cost that the government has paid for.

Yet ESAs do have a role in treating some people with chronic kidney disease, despite their dangers, Singh said.

The new FDA
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Anemia Harder to Treat in Black Children With Kidney Disease
2. Anemia tougher to tackle in black children with kidney disease
3. For Some on Dialysis, Anemia Drugs Pose Risks
4. FDA Tightens Controls on Anemia Drugs
5. Anemia drug not helpful for kidney disease patients
6. As FDA Eyes Prostate Cancer Drugs, Experts Urge Caution
7. Taking Flu Drugs While Pregnant Appears to Be Safe: Study
8. OTC Drugs May Work Differently in Obese Kids
9. Study finds that drugs used for treatment of influenza in pregnancy appear to be safe
10. BATTLE links potential biomarkers to drugs for lung cancer
11. Matching Tumor Types to Drugs Boosts Lung Cancer Outcomes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... This is a professional and in-depth study on ... a focus on the Chinese market. The report provides ... manufacturers and is a valuable source of guidance and ... This report provides a basic overview of the industry ... part, the report presents the company profile, product specifications, ...
(Date:12/25/2014)... Product liability lawsuits filed in the ... http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal court, ... in the U.S. District Court, Northern District of Ohio ... conference on January 7, 2015, at the Paul G. ... Palm Beach, Florida. The Conference is scheduled to begin ...
(Date:12/25/2014)... The short film “Color of Honor” by young ... a true 9/11 hero, Welles Remy Crowther. It has been ... hours of Nuremberg International Short Film Festival and the 8th ... screenwriter and director Luciana Lagana plays the mother of ... husband, Gregory Graham - Graham plays a heroic ...
(Date:12/25/2014)... December 25, 2014 When head lice hits ... in a frenzy to get rid of it while keeping ... in Coral Gables now have the solution right in their ... clinic location, Lice Troopers provides full spectrum head lice screening ... Gable area, including Sunset, Key Biscayne, Brickell, Coconut Grove, Kendall, ...
(Date:12/25/2014)... Overeating is common during the holidays, but there are strategies ... "Don,t arrive at a party hungry. It may seem ... attending a party, but deprivation leads to hunger, and hunger ... Hospital in Mount Kisco, N.Y., said in a hospital news ... and even to have a snack before attending a party ...
Breaking Medicine News(10 mins):Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 3Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:Coral Gables Florida Gets Ready to Be Lice-Free with Lice Troopers 2
... Smokerman Can,t because he smokes cigarettes... New anti-tobacco ads star a toy ... the health effects from his tobacco use. , ... Salt Lake City, ... Lake City today launched a new series of television ads starring a ...
... 11 The Grand Opening Celebration of Ocean,Blue ... from 7:00 until,10:00 p.m. Ocean Blue Plastic Surgery ... most prestigious addresses. Guests are invited to enjoy ... Plastic Surgery while,sampling hors d,oeuvres and sipping cocktails ...
... The Beryl Institute is seeking speakers,for its annual ... Worth,Metroplex. The theme for the conference is "The ... to improving customer service in,healthcare and will feature ... ways healthcare organizations can deliver,superior customer service., ...
... HealthCore, WellPoint,s health,outcomes research subsidiary, today presented ... in collaboration with the National Lipid Association,that ... American adults. The study,findings, presented during the ... Orleans, suggest that regardless of gains made ...
... General Nutrition Centers, Inc.,("GNC" the "Company" or "we"), ... reported its financial results for the third,quarter ended ... indirect wholly owned subsidiary of GNC Parent LLC,which ... ("Ares") and,Ontario Teachers, Pension Plan Board ("Teachers") through ...
... Before Holidays, WASHINGTON, Nov. 11 The American Red ... cards to service men,and women in the United States and ... the public is invited to send holiday,cards with their message ... Red Cross and Pitney Bowes will then screen cards for ...
Cached Medicine News:Health News:Anti-Tobacco Campaign Targets Twelve-and-Under Youth with Debut of "Smokerman" in New Television Ads 2Health News:Anti-Tobacco Campaign Targets Twelve-and-Under Youth with Debut of "Smokerman" in New Television Ads 3Health News:Ocean Blue Plastic Surgery to Open This Month on Brickell Avenue 2Health News:The Beryl Institute Announces Call for Speakers for 2009 Conference Dedicated to Healthcare Customer Service: 'The Pursuit of Excellence' 2Health News:Triglyceride Levels Continue to Rise in the United States Despite Increased Use of Cholesterol-Lowering Medications 2Health News:Triglyceride Levels Continue to Rise in the United States Despite Increased Use of Cholesterol-Lowering Medications 3Health News:Triglyceride Levels Continue to Rise in the United States Despite Increased Use of Cholesterol-Lowering Medications 4Health News:General Nutrition Centers, Inc. Reports Third Quarter 2008 Financial Results 2Health News:General Nutrition Centers, Inc. Reports Third Quarter 2008 Financial Results 3Health News:General Nutrition Centers, Inc. Reports Third Quarter 2008 Financial Results 4Health News:General Nutrition Centers, Inc. Reports Third Quarter 2008 Financial Results 5Health News:General Nutrition Centers, Inc. Reports Third Quarter 2008 Financial Results 6Health News:General Nutrition Centers, Inc. Reports Third Quarter 2008 Financial Results 7Health News:General Nutrition Centers, Inc. Reports Third Quarter 2008 Financial Results 8Health News:General Nutrition Centers, Inc. Reports Third Quarter 2008 Financial Results 9Health News:General Nutrition Centers, Inc. Reports Third Quarter 2008 Financial Results 10Health News:'Holiday Mail for Heroes' to Deliver One Million Cards to Service Members and Families 2Health News:'Holiday Mail for Heroes' to Deliver One Million Cards to Service Members and Families 3
(Date:12/24/2014)... CHENGDU, China, Dec. 24, 2014 /PRNewswire/  -- Tianyin ... a pharmaceutical company that specializes in the patented ... and active pharmaceutical ingredients (API) released unaudited preliminary ... year 2015. Fiscal Year 2015 Ended ... was $9.7 million compared with $14.7 million in ...
(Date:12/24/2014)... Dec. 24, 2014 Soligenix, Inc. (OTCQB: ... company developing products that address unmet medical needs ... announced today that on December 24, 2014 it ... The Company raised approximately $2.3 million in ... use the net proceeds from the offering to ...
(Date:12/24/2014)... , Dec. 24, 2014  Conkwest, Inc., the ... the proprietary Natural Killer (NK) cell-line platform, Neukoplast® ... Patrick Soon-Shiong , NantWorks founder, physician scientist ... agreement to purchase approximately $48 million of the ... the investment, he will be named Co-Chairman of ...
Breaking Medicine Technology:TPI Presents Unaudited Preliminary First Quarter Fiscal Year 2015 Financial Results 2TPI Presents Unaudited Preliminary First Quarter Fiscal Year 2015 Financial Results 3TPI Presents Unaudited Preliminary First Quarter Fiscal Year 2015 Financial Results 4TPI Presents Unaudited Preliminary First Quarter Fiscal Year 2015 Financial Results 5TPI Presents Unaudited Preliminary First Quarter Fiscal Year 2015 Financial Results 6TPI Presents Unaudited Preliminary First Quarter Fiscal Year 2015 Financial Results 7TPI Presents Unaudited Preliminary First Quarter Fiscal Year 2015 Financial Results 8TPI Presents Unaudited Preliminary First Quarter Fiscal Year 2015 Financial Results 9TPI Presents Unaudited Preliminary First Quarter Fiscal Year 2015 Financial Results 10TPI Presents Unaudited Preliminary First Quarter Fiscal Year 2015 Financial Results 11TPI Presents Unaudited Preliminary First Quarter Fiscal Year 2015 Financial Results 12Soligenix Announces Closing of Public Offering of Units 2Soligenix Announces Closing of Public Offering of Units 3Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 2Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 3Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 4Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 5
... Subjects with ALS, RICHMOND, Calif., Sept. 3 ... it has opened a Phase,2 clinical trial (SB-509-801) to ... degenerative motor-neuron disease for which there,are limited treatment options ... injectable formulation of a plasmid,encoding a zinc finger DNA-binding ...
... , - This Analysis Showed That Multaq(R) (Dronedarone) ... Atrial Fibrillation or Atrial Flutter,Already Adequately Treated by Antithrombotic ... the data from the ATHENA study,were presented today at ... Cardiology congress 2008, in Munich, Germany. Previous results,from the ...
Cached Medicine Technology:Sangamo BioSciences Initiates Phase 2 Clinical Trial of Treatment for Amyotrophic Lateral Sclerosis (ALS) 2Sangamo BioSciences Initiates Phase 2 Clinical Trial of Treatment for Amyotrophic Lateral Sclerosis (ALS) 3Sangamo BioSciences Initiates Phase 2 Clinical Trial of Treatment for Amyotrophic Lateral Sclerosis (ALS) 4Sangamo BioSciences Initiates Phase 2 Clinical Trial of Treatment for Amyotrophic Lateral Sclerosis (ALS) 5Further Analysis From ATHENA Study Showed That Multaq(R)(Dronedarone) Reduced the Risk of Stroke in Patients With Atrial Fibrillation 2Further Analysis From ATHENA Study Showed That Multaq(R)(Dronedarone) Reduced the Risk of Stroke in Patients With Atrial Fibrillation 3Further Analysis From ATHENA Study Showed That Multaq(R)(Dronedarone) Reduced the Risk of Stroke in Patients With Atrial Fibrillation 4Further Analysis From ATHENA Study Showed That Multaq(R)(Dronedarone) Reduced the Risk of Stroke in Patients With Atrial Fibrillation 5
Tilt Adapter for the 8000 Sliding Microtome to allow for orientation of the specimen....
... Microtome has a look that is revolutionary, a ... functions and capabilities that will please the most ... experience and knowledge but still breaking new ground ... will be the answer to many of your ...
Clock oil, 6 grams net...
Knife sharpening back for Standard Knife, C Profile...
Medicine Products: